Integrated regulatory network in Pseudomonas syringae reveals dynamics of virulence

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Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2

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A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration

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Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer

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Tumor-derived MMPs regulate cachexia in a Drosophila cancer model

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Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection

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PIN-LIKES Coordinate Brassinosteroid Signaling with Nuclear Auxin Input in Arabidopsis thaliana

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Mitochondrial NAD+ Controls Nuclear ARTD1-Induced ADP-Ribosylation

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Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment

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Transcriptional space-time mapping identifies concerted immune and stromal cell patterns and gene programs in wound healing and cancer

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Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection

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Fibroblast inflammatory priming determines regenerative versus fibrotic skin repair in reindeer

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Liver and muscle circadian clocks cooperate to support glucose tolerance in mice

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Neuroinflammatory disease disrupts the blood-CNS barrier via crosstalk between proinflammatory and endothelial-to-mesenchymal-transition signaling

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Defects in a liver-bone axis contribute to hepatic osteodystrophy disease progression

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The Circadian Clock Gene Circuit Controls Protein and Phosphoprotein Rhythms in Arabidopsis thaliana

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Parinarioidins A-B,unprecedented flavonoids from the bark of Brosimum parinarioides Ducke

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Predicting Successful Generation and Inhibition of Seizure-like Afterdischarges and Mapping Their Seizure Networks Using fMRI

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Opto-katanin,an optogenetic tool for localized,microtubule disassembly

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Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases

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