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Regulation of gene expression by dopamine may play an important role in learning, reward, and addiction. Hyman and colleagues now report the characterization of ania-6, a novel cyclin that associates with RNA polymerase II and is induced by dopamine or cocaine in the neostriatum. Ania-6 may thus provide a link between dopamine and gene expression at the level of mRNA processing. 相似文献
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C A van der Sande T Kulkens A B Kramer I J de Wijs H van Heerikhuizen J Klootwijk R J Planta 《Nucleic acids research》1989,17(22):9127-9146
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Philimonenko VV Zhao J Iben S Dingová H Kyselá K Kahle M Zentgraf H Hofmann WA de Lanerolle P Hozák P Grummt I 《Nature cell biology》2004,6(12):1165-1172
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