Editor's Note

As readers of Soviet Psychology are aware, it has been my policy over the years to present historical materials that are pertinent to understanding contemporary Soviet and world psychology. By and large, I have come upon such materials through discussions with Soviet scholars or by following the lead in relevant articles. When I first read Jaan Valsiner's lucid and informative book Developmental Psychology in the Soviet Union, I was immediately struck by the gold mine of materials to which Professor Valsiner had succeeded in gaining access. First among these was the work of Mikhail Basov, to whom Valsiner devoted an especially illuminating chapter in his monograph.     

Activity: Structure,Genesis, and Units of Analysis

One of the most remarkable events in Soviet psychology in the second half of the '70s was the discussion of the problem of the relationship between communication and activity [8,13,18,19,21,23]. We considered the following approach to the problem, which we here present in its most general form, the most constructive: Communication and activity are undoubtedly interrelated; but communication (in contrast to perception, memory, etc.) is not usefully regarded as simply one type of activity as it is analyzed in terms of Leont'ev's paradigm activity—action—operation, motive—goal—condition. This approach to the problem is useful primarily for advancing the theory of activity: it points sharply to the very essential point, insufficiently developed in the theory of activity, that analysis of social environments and the mechanisms of human activity is both collective and individual.     

Activity: Structure,Genesis, and Unit of Analysis

One of the most notable phenomena in Soviet psychology since the late '70s has been discussion of the relationship between communication and activity [8,13,18,19,21,23]. I consider the following formulation of the problem, given here in its most general form, the most constructive: communication and activity are indubitably interrelated, but communication (in contrast to perception, memory, etc.) cannot, in any constructive way, be regarded as a type of activity and analyzed within the framework of Leont 'ev's paradigm (activity—action—operation; motive—goal—condition). This formulation of the problem is useful primarily in terms of the further progress of the theory of activity: it quite incisively focuses on one essential point that has been inadequately dealt with in the theory of activity, namely, an analysis of the social means and mechanisms of human activity, both collective and individual.     

A teleosemantic approach to information in the brain

The brain is often taken to be a paradigmatic example of a signaling system with semantic and representational properties, in which neurons are senders and receivers of information carried in action potentials. A closer look at this picture shows that it is not as appealing as it might initially seem in explaining the function of the brain. Working from several sender-receiver models within the teleosemantic framework, I will first argue that two requirements must be met for a system to support genuine semantic information: 1. The receiver must be competent—that is, it must be able to extract rewards from its environment on the basis of the signals that it receives. 2. The receiver must have some flexibility of response relative to the signal received. In the second part of the paper, this initial framework will be applied to neural processes, pointing to the surprising conclusion that signaling at the single-neuron level is only weakly semantic at best. Contrary to received views, neurons will have little or no access to semantic information (though their patterns of activity may carry plenty of quantitative, correlational information) about the world outside the organism. Genuine representation of the world requires an organism-level receiver of semantic information, to which any particular set of neurons makes only a small contribution.     

A Communicative Approach to Using Computers for Cultivating Cognitive Skills and Communication in Young Children

An analysis of a child's cognitive activity in the use of computers may be carried out with respect to the child's verbalization of the objective world in the presence of one other person or several people. This approach [1-3] also includes the dialogic nature of learning, and thus differs fundamentally from investigations that examine development only in individual problem solving. In contrast to the approach of Soviet investigators, who stress the role of social situations in the formation of individual concepts in a person, the dominant approach in the USA has, until quite recently, been child-oriented in all areas of learning and in child psychology.     

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

The aim of this methods paper is to describe how to implement a neuroimaging technique to examine complementary brain processes engaged by two similar tasks. Participants'' behavior during task performance in an fMRI scanner can then be correlated to the brain activity using the blood-oxygen-level-dependent signal. We measure behavior to be able to sort correct trials, where the subject performed the task correctly and then be able to examine the brain signals related to correct performance. Conversely, if subjects do not perform the task correctly, and these trials are included in the same analysis with the correct trials we would introduce trials that were not only for correct performance. Thus, in many cases these errors can be used themselves to then correlate brain activity to them. We describe two complementary tasks that are used in our lab to examine the brain during suppression of an automatic responses: the stroop¹ and anti-saccade tasks. The emotional stroop paradigm instructs participants to either report the superimposed emotional ''word'' across the affective faces or the facial ''expressions'' of the face stimuli^1,2. When the word and the facial expression refer to different emotions, a conflict between what must be said and what is automatically read occurs. The participant has to resolve the conflict between two simultaneously competing processes of word reading and facial expression. Our urge to read out a word leads to strong ''stimulus-response (SR)'' associations; hence inhibiting these strong SR''s is difficult and participants are prone to making errors. Overcoming this conflict and directing attention away from the face or the word requires the subject to inhibit bottom up processes which typically directs attention to the more salient stimulus. Similarly, in the anti-saccade task^3,4,5,6, where an instruction cue is used to direct only attention to a peripheral stimulus location but then the eye movement is made to the mirror opposite position. Yet again we measure behavior by recording the eye movements of participants which allows for the sorting of the behavioral responses into correct and error trials⁷ which then can be correlated to brain activity. Neuroimaging now allows researchers to measure different behaviors of correct and error trials that are indicative of different cognitive processes and pinpoint the different neural networks involved.     

Reproductive under-performance of tsetse flies in the laboratory, related to feeding frequency

Abstract. The rates of development of the eggs and larvae in utero and the next two developing ovarioles were measured by ovarian dissection on each day of the pregnancy cycle in tsetse, Glossina morsitans, subject to different feeding regimes. Compared with flies fed four times per pregnancy cycle, flies fed three times per cycle showed a lower pupal production rate (70%), the same (zero) adult mortality, a slightly slower growth rate of the larva and second ovariole only from day 8 onwards, but the same growth rate of the first ovariole. Flies fed only twice per pregnancy cycle produced no pupae, suffered 18% adult mortality and showed a significantly slower growth rate of the larva and second ovariole from days 6 and 7 respectively, but still the growth rate of the first ovariole was barely affected. Flies offered food three times or twice per pregnancy cycle engorged fully at every opportunity, but 16.5% of the flies offered food four times per cycle did not feed on every occasion, while 12–22% did not engorge fully on days 3, 5 or 7. In assessing the applicability of these laboratory results to the field situation the following points must be borne in mind: in the laboratory flies take smaller mean blood meals than in the field; during protein production associated with larval growth the proportion of the blood meal lost to transformation and excretory costs is less than during normal lipid metabolism; the balance between the tsetse's known fertility rate and adult and pupal mortality rates reveals that the abortion rate in the field must be extremely low. The high abortion rates usually observed in laboratory colonies, even when flies are offered food daily_l would be quite untenable in the field and indicate that laboratory conditions impose physiological stresses on the flies that are quite different from those in the field. These facts indicate that three field-sized meals may be sufficient to meet the energy demands of normal larval development in the field.     

A Comparative Study of the Level of Locomotor Activity Throughout Postembryonic Development of Two Cricket Species: Acheta domesticus L. and Gryllus bimaculatus De Geer (Ensifera: Gryllidae)

The level of locomotor activity throughout the entire postembryonic development of two crickets, Acheta domesticus (L.) and Gryllus bimaculatus De Geer, has been investigated under controlled laboratory conditions. In both species the level of activity was subject to changes in the course of their development. Activity was reduced during the molting periods, creating a fluctuating pattern, yet in both species it was significantly higher at the end of development than at the beginning. Although the general trend of changes occurring was similar in both species, there were significant between-species differences in their pattern. The activity of A. domesticus larvae seemed to increase more gradually and it was significantly higher than the activity of G. bimaculatus larvae.     

Impact of Compost on Metals Phytostabilization Potential of Two Halophytes Species

Phytostabilization of heavy metals in contaminated soils should be subject to two conditions, the first is the choice plant must be able to stabilize heavy metals in soil, the second is the plant material which produced from the phytostabilization process must be safe and useful to avoid overload on environmental system. A field experiment was conducted out to evaluate the phytostabilization potential of two halophytes species (Atriplex lentiformis and Atriplex undulata). Compost at rates of 0, 15 and 30 ton ha^?1 was used to examine its role in plant growth and heavy metals uptake. The high rate of compost (30 ton ha^?1) decreased zinc (Zn) concentrations in the leaves of A. lentiformis and A. undulata by 15.8 and 13.0%, while lead (Pb) in the leaves decreased by 37.6 and 35.2% respectively. Despite the extremely high total heavy metals concentrations in the studied soil, plants of Atriplex were able to grow and maintain shoots metals content below the toxic level and the produced plant materials had a high nutritive value compared to the conventional forage crops. Phosphorus (P) and chloride (Cl) in the roots of Atriplex plants play important function in heavy metals phytostabilization mechanism by the two halophytes plants.     

SU(VAR)3-9 is a conserved key function in heterochromatic gene silencing

This review summarizes genetic, molecular and biochemical studies of the SU(VAR)3-9 protein and the evidence for its key role in heterochromatin formation and heterochromatic gene silencing. The Su(var)3-9 locus was first identified as a dominant modifier of position-effect variegation (PEV) in Drosophila melanogaster. Together with Su(var)2-5 and Su(var)3-7, Su(var)3-9 belongs to the group of haplo-suppressor loci which show a triplo-dependent enhancer effect. All three genes encode heterochromatin-associated proteins. Su(var)3-9 is epistatic to the PEV modifier effects of Su(var)2-5 and Su(var)3-7, and it also dominates the effect of the Y chromosome on PEV. These genetic data support a central role of the SU(VAR)3-9 protein in heterochromatic gene silencing, one that is correlated with its activity as a histone H3-K9 methyltransferase (HMTase). In fact, SU(VAR)3-9 is the main chromocenter-specific HMTase of Drosophila. SU(VAR)3-9 and HP1, the product of Su(var)2-5, are main constituents of heterochromatin protein complexes and the interaction between these two proteins is interdependent. Functional analysis in fission yeast, Drosophila and mammals demonstrate that SU(VAR)3-9-dependent gene silencing processes are conserved in these organisms. This is also demonstrated by the rescue of Drosophila Su(var)3-9 mutant phenotypes with human SUV39H1 transgenes.     

Guest Editor's Introduction : Bakhtin's Dialogic Pedagogy

This issue of Soviet Psychology opens with an extensive round-table discussion of the shortcomings of institutionalized psychology in light of the ongoing changes in Soviet society associated with Mikhail Gorbachev's policies of perestroika (restructuring) and glasnost (openness). The participants varied widely in their professional expertise, thus providing an unusually broad view of Soviet psychologists' public views about the problems facing their science.     

Artificial womb technology and clinical translation: Innovative treatment or medical research?

In 2017 and 2019, two research teams claimed ‘proof of principle’ for artificial womb technology (AWT). AWT has long been a subject of speculation in bioethical literature, with broad consensus that it is a welcome development. Despite this, little attention is afforded to more immediate ethical problems in the development of AWT, particularly as an alternative to neonatal intensive care. To start this conversation, I consider whether experimental AWT is innovative treatment or medical research. The research–treatment distinction, pervasive in regulation worldwide, is intended to isolate research activities and subject them to a greater degree of oversight. I argue that there is a tendency in the literature to conceptualize AWT for partial ectogenesis as innovative treatment. However, there are sufficiently serious ethical concerns with experimental AWT that mean that it must not be first used on humans on the basis that it is a ‘beneficial treatment’. First, I outline the prospects for translation of AWT animal studies into treatment for human preterms. Second, I challenge the conceptualizations of experimental AWT as innovative treatment. It must be considered medical research to reflect the investigatory nature of the process and guarantee sufficient protections for subjects. Identifying that AWT is research is crucial in formulating further ethico-legal questions regarding the experimental use of AWT. Third, I demonstrate that clinical trials will be a necessary part of the clinical translation of AWT because of requirements laid out by regulators. I consider the justification for clinical trials and highlight some of the crucial ethical questions about the conditions under which they should proceed.     

The Development Of Speech Among Children In Communication With Adults During The First Seven Years

This article is a brief presentation of the findings from a study of the origin and development of speech and its communicative functions done within the context of a concept of the development of communication. This context presupposes two distinct aspects of an approach to the problem of the development of speech in children. The first of these is how communication itself is understood; and the second is how the relation between speech and communication is conceived.     

International environmental implications of Soviet development of the Volga River

Hydrologic alteration of major rivers has the potential for environmental damage on an international scale. Soviet regulation of the Volga River is a case in point. Iran, bordering on the Caspian Sea to which the Volga is tributary, has been harmed by changes in the sea's physical and biological character which are partially attributable to Soviet modification of the Volga's natural flow regime. Soviet plans for southward diversion of flow from the European Arctic and Siberia, partially intended to alleviate the Caspian problem, could pose an even more serious international hazard. Possible adverse consequences range from further imperiling the survival of the Atlantic salmon to hemispheric, perhaps even global, climatic changes. The already apparent consequences of Volga development and possible future ramifications of related diversion measures emphasize the need for caution as well as international cooperation and consultation in planning the alteration of major river basins.     

Peroxidase activity in hooded and awned barley at successive stages of development

The hooded (KK) and awned (kk) genotypes of barley differ in the amount of peroxidase activity at various stages of development. In hooded, this activity is at most stages higher than in awned, but it varies more from one stage to another, so that at certain stages, particularly the first leaf stages of young plants, it is lower. The peroxidase enzymes of the two genotypes are alike in electrophoretic mobility. Since peroxidase activity is particularly high in meristems of hooded at the beginning of their transition from the vegetative to the flowering condition, which is shortly before the first effects on morphogenesis can be observed, a connection between high peroxidase activity and the morphogenetic effects appears likely.     

Physical and functional interaction between d-ribokinase and topoisomerase I has opposite effects on their respective activity in Mycobacterium smegmatis and Mycobacterium tuberculosis

d-ribose is an essential component of multiple important biological molecules and must first be phosphorylated by ribokinase before entering metabolic pathways. However, the function and regulation of ribokinases in Mycobacterium tuberculosis, the causative agent of tuberculosis, and its related species are largely unknown. In this study, we have characterized the activities of two putative ribokinases, Rv2436 and Ms4585, from M. tuberculosis and Mycobacterium smegmatis, respectively. The mycobacterial topoisomerase I (TopA) was found to physically interact with its ribokinase both in vitro and in vivo. By creating two ribokinase mutants that showed defective interactions with TopA, we further showed that the interaction between ribokinase and TopA had opposite effects on their respective function. While the interaction between the two proteins inhibited the ability of TopA to relax supercoiled DNA, it stimulated ribokinase activity. A cross-regulation assay revealed that the interaction between the two proteins was conserved in the two mycobacterial species. Thus, we uncovered an interplay between ribokinase and topoisomerase I in mycobacteria, which implies the existence of a novel regulatory strategy for efficient utilization of d-ribose in M. tuberculosis that may be useful in stressful environments with restricted access to nutrients.     

A thrombin inhibitor from the gut of <Emphasis Type="Italic">Boophilus microplus</Emphasis> ticks

A thrombin inhibitor was identified for the first time in the gut of the cattle tick Boophilus microplus. Here we present the partial purification and characterization of this new molecule, which was purified from the gut extract by three chromatographic steps: ion-exchange, gel filtration and affinity chromatography in a thrombin–Sepharose resin. In SDS-PAGE the inhibitor showed an apparent molecular mass of circa 26 kDa, which is different from the two thrombin inhibitors present in the saliva of this tick. The new inhibitor delays bovine plasma clotting time and inhibits both thrombin induced fibrinogen clotting and thrombin induced platelet aggregation. However, it does not interfere with thrombin amidolytic activity upon a small substrate (H-D-Phe-Pip-Arg-para-nitroanilide), which does not require binding to thrombin exosites. Therefore, the inhibitor does not block thrombin active site, although it must interfere with one of the thrombin exosites. B. microplus gut thrombin inhibitor (BmGTI) is also capable of enhancing activated protein C (APC) activity upon its specific substrate (H-D-Glu-Pro-Arg-para-nitroanilide), an activity never described before among B. microplus molecules.     

Weissia papillosissima Laz. (Pottiaceae,Musci), a species new to the European bryophyte flora

Abstract

Weissia papillosissima Laz. is reported for the first time in Europe at different localities in the Iberian Peninsula. Previously it was known only from Tadhikistan in the former Soviet Union. The. species is described and illustrated and its distribution mapped and discussed.     

Toward the Problem of Stages in the Mental Development of Children

The problem of stages' in the mental development of the child is the fundamental problem of child psychology. Elaboration of this problem has important theoretical significance since it is by determining the stages of mental development and by discovering the patterns of transition from one stage to the next that psychology will eventually solve the problem of the motive forces of mental development. We contend that every conception of the motive forces of mental development must first be tested on the "proving grounds" of the theory of developmental stages.