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1.
Tooth loss and its relationship with protein intake by elderly Brazilians—A structural equation modelling approach
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Objective
This study aimed at assessing the relationship between self‐perceived tooth loss and wearing dentures, on the one hand, and the consumption of protein, on the other hand, among the elderly population of Botucatu, SP. Food consumption tends to decrease with ageing, especially protein intake, and one of the causes could be the precariousness of oral health. Several risk factors associated with deficient dietary protein intake have been identified, namely greater physical dependence, reduced caloric intake and food insecurity, but no studies have analysed whether tooth loss and prostheses interfere with protein intake.Methods
An interview was conducted among 365 elderly individuals, in which we examined oral health‐related quality of life (OHRQoL) as the only latent variable, in a 24‐hour nutritional assessment dietary recall repeated 3 times, conducted in person by a trained nutritionist and also performed an analysis of nutritional needs using the Nutrition Data System Research (NDSR) Program.Results
The structural equation model, performed using Stata v.14, showed that lack of teeth (standardised coefficient [SC] = 0.21, P < .001), and prosthesis use (SC = ?0.21, P < .001) was associated with OHRQoL. Lack of teeth had a direct effect on the consumption of animal protein (SC = 0.08, P = .02), a strong total effect on animal protein intake (SC = 0.51, P = .04) and a medium effect on total protein intake (SC = 0.20, P = .03), adjusted for confounders (depression and medical problems).Conclusion
Tooth loss had a strong and significant total effect on animal protein intake and a medium effect on total protein intake among elderly Brazilians. 相似文献2.
Hsiao KC Brissette RE Wang P Fletcher PW Rodriguez V Lennick M Blume AJ Goldstein NI 《Proteome science》2003,1(1):1-9
Background
Hotspots are defined as the minimal functional domains involved in protein:protein interactions and sufficient to induce a biological response. 相似文献3.
I-Shan Chen Zen-Kong Dai Donald G Welsh Ing-Jun Chen Bin-Nan Wu 《Journal of biomedical science》2011,18(1):2
Background
This study investigates whether protein kinase G (PKG), protein kinase A (PKA) and protein kinase C (PKC) are involved in the regulatory mechanisms of store-operated channel (SOC) in pulmonary arteries. 相似文献4.
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks 总被引:1,自引:0,他引:1
Background
This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated with these clusters. 相似文献5.
Background
Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a sequence is still very challenging and largely unsolved. 相似文献6.
7.
Background
Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techniques to predict protein folding pathways are computationally intensive and are suitable only for small proteins. 相似文献8.
Aranganathan Shanmuganathan Thallapuranam Krishnaswamy Suresh Kumar Chiy-Mey Huang Chin Yu Der-Hang Chin 《Journal of biomedical science》2009,16(1):48-11
Background
Neocarzinostatin is a potent antitumor drug consisting of an enediyne chromophore and a protein carrier. 相似文献9.
Background
Conserved protein sequence regions are extremely useful for identifying and studying functionally and structurally important regions. By means of an integrated analysis of large-scale protein structure and sequence data, structural features of conserved protein sequence regions were identified. 相似文献10.
Background
β-turns are secondary structure elements usually classified as coil. Their prediction is important, because of their role in protein folding and their frequent occurrence in protein chains. 相似文献11.
Neal E Beeman Heidi K Baumgartner Patricia G Webb Jerome B Schaack Margaret C Neville 《BMC cell biology》2009,10(1):85
Background
Occludin is a tetraspanin protein normally localized to tight junctions. The protein interacts with a variety of pathogens including viruses and bacteria, an interaction that sometimes leads to its extrajunctional localization. 相似文献12.
Paolo Mereghetti Maria Luisa Ganadu Elena Papaleo Piercarlo Fantucci Luca De Gioia 《BMC bioinformatics》2008,9(1):66
Background
The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure refinement, which has been recently identified as one of the bottlenecks limiting the quality and usefulness of protein structure prediction. 相似文献13.
Luonan Chen Ling-Yun Wu Yong Wang Shihua Zhang Xiang-Sun Zhang 《BMC structural biology》2006,6(1):18-14
Background
Protein structure comparison is one of the most important problems in computational biology and plays a key role in protein structure prediction, fold family classification, motif finding, phylogenetic tree reconstruction and protein docking. 相似文献14.
William A Maltese Gwendolyn Soule William Gunning Edward Calomeni Brandy Alexander 《BMC cell biology》2002,3(1):25-17
Background
Members of the Rab GTPase family regulate intracellular protein trafficking, but the specific function of Rab24 remains unknown. Several attributes distinguish this protein from other members of the Rab family, including a low intrinsic GTPase activity. 相似文献15.
Background
Protein-protein interaction information can be used to predict unknown protein functions and to help study biological pathways. 相似文献16.
Background
It is well known that different species have different protein domain repertoires, and indeed that some protein domains are kingdom specific. This information has not yet been incorporated into statistical methods for finding domains in sequences of amino acids. 相似文献17.
Background
Current protein clustering methods rely on either sequence or functional similarities between proteins, thereby limiting inferences to one of these areas. 相似文献18.
Background
Accurate protein loop structure models are important to understand functions of many proteins. Identifying the native or near-native models by distinguishing them from the misfolded ones is a critical step in protein loop structure prediction. 相似文献19.
Background
The periplasmic High Temperature Requirement protein A (HtrA) plays important roles in bacterial protein folding and stress responses. However, the role of chlamydial HtrA (cHtrA) in chlamydial pathogenesis is not clear. 相似文献20.