Structural insights into DarT toxin neutralization by cognate DarG antitoxin: ssDNA mimicry by DarG C-terminal domain keeps the DarT toxin inhibited

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A replication fork determinant for the establishment of sister chromatid cohesion

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Molecular basis for the reversible ADP-ribosylation of guanosine bases

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Ligation of newly replicated DNA controls the timing of DNA mismatch repair

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Dynamic stem cell selection safeguards the genomic integrity of the epidermis

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Proteomic profiling reveals distinct phases to the restoration of chromatin following DNA replication

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Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

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Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M

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Strand-specific ChIP-seq at DNA breaks distinguishes ssDNA versus dsDNA binding and refutes single-stranded nucleosomes

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Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens

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Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase

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Distribution and phasing of sequence motifs that facilitate CRISPR adaptation

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Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th century

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Structural basis for recruitment of the CHK1 DNA damage kinase by the CLASPIN scaffold protein

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HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells

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DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes

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A DddA ortholog-based and transactivator-assisted nuclear and mitochondrial cytosine base editors with expanded target compatibility

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Paternal transmission of the Wolbachia CidB toxin underlies cytoplasmic incompatibility

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Dynamic Assembly and Disassembly of the Human DNA Polymerase δ Holoenzyme on the Genome In Vivo

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Dephosphorylation of the pre-initiation complex is critical for origin firing

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