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1.
1. To describe quantitatively and to deliminate nine EEG sleep patterns, mean values and standard deviations of abundances of the frequencies 0.8 ... 1.8 c/sec, 2...3.5 c/sec, 4...13c/sec, 14 to 17 c/sec, 18 to 22 c/sec, and 23 to 40 c/sec as well as of the average amplitudes in selected frequency ranges were calaculated and the distributions represented. 2. All nine EEG activity patterns could be separated by means of univariate and multivariate analyses of variance on the basis of all 28 as well as the 17 indispensable variables. 3. In the course of a stepwise reduction of variables within the framework of a linear discriminant analysis an optimal set of 17 variables was determined for the separation of the patterns, comprising: the percent quantity of the frequencies 0.8 ... 3.5 c/sec, 7 ... 9 c/sec and 18 to 40 c/sec as well as the average amplitudes in the frequency ranges 0.8 to 3.5 c/sec and 7.5 to 40 c/sec. 4. By linear regression analyses it could be shown that the sleep scording system used, can be reflected on an interval scale with the aid of discriminant functions; this can be achieved on the basis of the optimal set of variables as well as of the five most indispensable variables. 5. Finally the degree of the objectivity of the scoring procedures was demonstrated. Advantages and disadvantages of sleep scoring systems were discussed and possibilities of the utilization of results suggested, also in respect to the further development of the automatic recognition of EEG activity patterns. 相似文献
2.
1. In order to determine the variable distributions of 5 activation dependent EEG activity patterns occurring during visual information processing, mean values and standard deviations of the percental quantities of the frequencies 4, 5, ..., 13 Hz, 14 to 20 Hz and 21 to 30 Hz, as well as the mean amplitudes in the frequency bands 3.5 ... 7.4 Hz, 7.5 ... 13.4 Hz and 13.5 to 30 Hz were determined on corresponding to 10 s samples. It could be demonstrated by regression analysis that an interval scale level can be assumed already on the basis of cethe percental quantities in the three last mentioned frequency bands. 2. On the basis of 18 relevant variables, all the adjacent activity patterns could be separated from each other by means of univariate variance analysis at pairwise mean value comparison by at least two variables. 3. After stepwise reduction of dispensable variables in the framework of a linear discriminance analysis an optimal set of variables was determined, comprising the percental quantities of the frequencies 4, 5, 6, 10, 12 Hz, and 14 to 20 Hz, as well as the mean value of the amplitudes in the frequency band 3.5 to 7.4 Hz. In 4 our of 5 elementary discriminance functions, the mean values calculated for each pattern were significantly distinguishable from each other (analysis of variance, Newman-Keuls test). 4. By linear regression analysis it could be shown that the classification system of the EEG activity patterns at visual information processing can be mapped on an interval scale after the reduction of variables, too. Finally, data about the reliability of the scoring procedure are presented. 相似文献
3.
Parameswaran Mahadeva Iyer Catriona Egan Marta Pinto-Grau Tom Burke Marwa Elamin Bahman Nasseroleslami Niall Pender Edmund C. Lalor Orla Hardiman 《PloS one》2015,10(6)
Background
Amyotrophic Lateral Sclerosis (ALS) is heterogeneous and overlaps with frontotemporal dementia. Spectral EEG can predict damage in structural and functional networks in frontotemporal dementia but has never been applied to ALS.Methods
18 incident ALS patients with normal cognition and 17 age matched controls underwent 128 channel EEG and neuropsychology assessment. The EEG data was analyzed using FieldTrip software in MATLAB to calculate simple connectivity measures and scalp network measures. sLORETA was used in nodal analysis for source localization and same methods were applied as above to calculate nodal network measures. Graph theory measures were used to assess network integrity.Results
Cross spectral density in alpha band was higher in patients. In ALS patients, increased degree values of the network nodes was noted in the central and frontal regions in the theta band across seven of the different connectivity maps (p<0.0005). Among patients, clustering coefficient in alpha and gamma bands was increased in all regions of the scalp and connectivity were significantly increased (p=0.02). Nodal network showed increased assortativity in alpha band in the patients group. The Clustering Coefficient in Partial Directed Connectivity (PDC) showed significantly higher values for patients in alpha, beta, gamma, theta and delta frequencies (p=0.05).Discussion
There is increased connectivity in the fronto-central regions of the scalp and areas corresponding to Salience and Default Mode network in ALS, suggesting a pathologic disruption of neuronal networking in early disease states. Spectral EEG has potential utility as a biomarker in ALS. 相似文献4.
Hughes SW Lörincz M Cope DW Blethyn KL Kékesi KA Parri HR Juhász G Crunelli V 《Neuron》2004,42(2):253-268
In relaxed wakefulness, the EEG exhibits robust rhythms in the alpha band (8-13 Hz), which decelerate to theta (approximately 2-7 Hz) frequencies during early sleep. In animal models, these rhythms occur coherently with synchronized activity in the thalamus. However, the mechanisms of this thalamic activity are unknown. Here we show that, in slices of the lateral geniculate nucleus maintained in vitro, activation of the metabotropic glutamate receptor (mGluR) mGluR1a induces synchronized oscillations at alpha and theta frequencies that share similarities with thalamic alpha and theta rhythms recorded in vivo. These in vitro oscillations are driven by an unusual form of burst firing that is present in a subset of thalamocortical neurons and are synchronized by gap junctions. We propose that mGluR1a-induced oscillations are a potential mechanism whereby the thalamus promotes EEG alpha and theta rhythms in the intact brain. 相似文献
5.
According to the results of psychological testing, persons aged 18 to 21 years were divided into four groups, women and men with low and high productivity of divergent (creative, nonroutine) thinking (n = = 18 to 23). Results of EEG recording (19 leads) were used for calculation of the coherence coefficients for oscillations of the delta, theta, alpha1, alpha2, alpha3, beta, and gamma frequencies in lead pairs and estimation of integral indices of coherence within the anterior and posterior cortical regions and between these zones (interaction coefficients, IC1-IC3, respectively). EEG was recorded in the resting state and in the course of resolving convergent- and divergent-type cognitive test tasks. It was found that, during the performance of tests of both types, men with a higher productivity of divergent thinking demonstrated significantly higher values of IC1 (that characterizes the coherence in associative linkages within the anterior cortex) for oscillations of all EEG frequency ranges compared with the respective estimates for “low-creative” men. Similar increments were typical of the IC2 values for low- and midfrequency EEG rhythms (delta, theta, and alpha). At the same time, values of the “interregional” IC3 for theta, beta, and gamma activity in “high-creativity” men were significantly lower. In women of both groups (low and high creativity), such specificity of the IC1-IC3 patterns was practically not observed, i.e., the respective aspect demonstrated clear gender specificity. The sex of the subjects and type of the performed cognitive tests could not be considered factors significantly affecting the calculated absolute IC values. The observed specificities of integral coherence indices are probably associated with different strategies of the performance of cognitive tasks in men and women. Our findings allow us to believe that the above interrelations between integrated coherence indices can be used as EEG markers of high productivity of divergent thinking in men. The more flexible strategies of thinking in women are probably related to more variable neurophysiological cortical mechanisms (compared with those in men), and this type of organization is not clearly reflected in the pattern of intracortical interactions estimated by coherence indices. 相似文献
6.
《Electronic Notes in Theoretical Computer Science》1991,80(1):16-20
The relationship between the latencies and amplitudes of the N1 and P2 components of the visual evoked potential (VEP) and the psychophysiological state of the brain immediately preceding the time of the stimulus has been investigated in 7 male subjects. Power spectral measures in the delta, theta, alpha and beta bands of the 1 sec pre-stimulus EEG were used to assess the brain state, and low intensity flashes, delivered randomly between 2 and 6 whole seconds, were used as the stimuli. Trials were ranked separately according to the relative amounts of pre-stimulus power in each EEG band and were partitioned into groups by an equal pre-stimulus spectral power criterion. Averaged EPs were computed from these groups and multiple regression analysis was used to relate pre-stimulus spectral power values to EP features. Five of the 7 subjects displayed consistent increases in N1-P2 amplitude as a function of increasing pre-stimulus relative alpha power. The between-subjects effect of pre-stimulus EEG on N1 latency was small, but was moderate for P2 latency (both significant). Both N1 and P2 latency were found to decrease with increasing amounts of pre-stimulus relative delta and theta power. 相似文献
7.
The EEG mapping study tested age-related changes in power of EEG rhythms from delta to gamma ranges under healthy cognitive aging associated with preserved cognitive abilities and involvement in complex professional activity. 32 subjects of higher age group (HAG, mean age 65.1 +/- 1.18, 14 men and 18 women) and 33 subjects of lower age group (LAG mean age 22.1 +/- 0.38, 18 men and 15 women) participated in the study. Mean power of slow (delta, theta and alpha2) activity decreased and of fast activity (beta, gamma) increased as subject age increased. Compared to subjects of LAG subjects of HAG displayed a reduction in heterogeneity of EEG activity across recording sites. Centro-temporal gradients of power for frequency ranges from delta to beta2 and frontoparietal gradients and hemispheric asymmetry for alpha and beta1 rhythms were smoothed in subjects of HAG. These results suggest that observed age-related changes in baseline EEG may be the prerequisite for compensatory neural recruitment that may be associated as with allocation of more resources in cognitive processes so with reorganization of cortical networks including areas susceptible to physiological changes with aging. 相似文献
8.
Frequency-power spectra of the EEG evoked by repeptitive photic stimulation and of the background EEG were studied during childhood in 43 awake subjects aged between 2 months and 14 years. EEG activity was recorded from the middle parieto-occipital region with the aid of a 1-channel analyzer Lysograf-Alvar, analysing 16 frequencies in the range from 2 to 28 c/sec. The responsiveness of the central nervous system to flickering light improved in the course of childhood in parallel with the significant decline of delta activity and with the prominent increase of alpha intensity in the resting EEG. The 4th month of life appeared to be a marked turning point in the development of evoked and background EEGs. From that age, the bioelectric power at the flash rate corresponding to photic "driving" began to increase together with the highest and optimal driving frequencies. The flash rate, at which evoked potentials changed into the "driven" rhythm, also shifted towards higher frequencies. Subsequently, the amount of energy in the resting EEG increased significantly within the theta, alpha and beta bands and, on the contrary, a prominent decline was observed in the delta range. Marked ontogenetic changes at this age closely coincided with the rapid development of exogenous fibres in the occipital cortex, including the thalamo-cortical conncetions, and fibres of the neuropil in cortical layer I, which might play an important role in the genesis of background and "driven" in the occipital region. 相似文献
9.
Gregor Leicht Stefan Troschütz Christina Andreou Evangelos Karamatskos Matthias Ertl Dieter Naber Christoph Mulert 《PloS one》2013,8(12)
Background
The processing of reward and punishment stimuli in humans appears to involve brain oscillatory activity of several frequencies, probably each with a distinct function. The exact nature of associations of these electrophysiological measures with impulsive or risk-seeking personality traits is not completely clear. Thus, the aim of the present study was to investigate event-related oscillatory activity during reward processing across a wide spectrum of frequencies, and its associations with impulsivity and sensation seeking in healthy subjects.Methods
During recording of a 32-channel EEG 22 healthy volunteers were characterized with the Barratt Impulsiveness and the Sensation Seeking Scale and performed a computerized two-choice gambling task comprising different feedback options with positive vs. negative valence (gain or loss) and high or low magnitude (5 vs. 25 points).Results
We observed greater increases of amplitudes of the feedback-related negativity and of activity in the theta, alpha and low-beta frequency range following loss feedback and, in contrast, greater increase of activity in the high-beta frequency range following gain feedback. Significant magnitude effects were observed for theta and delta oscillations, indicating greater amplitudes upon feedback concerning large stakes. The theta amplitude changes during loss were negatively correlated with motor impulsivity scores, whereas alpha and low-beta increase upon loss and high-beta increase upon gain were positively correlated with various dimensions of sensation seeking.Conclusions
The findings suggest that the processing of feedback information involves several distinct processes, which are subserved by oscillations of different frequencies and are associated with different personality traits. 相似文献10.
Razumnikova OM 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》2000,50(6):921-932
The relationships between some characteristics of EEG topographic maps and personality traits (extraversion-introversion, sensation-intuition, thinking-feeling, judging-impulsiveness) by the Keirsey's Type Inventory were studied in 46 17-20-year-old men). The most considerable distinctions in the spatial organization of the EEG were observed between the functions sensation and intuition. The high-sensation responders were characterized by higher EEG power in the theta 1, 2 and alpha 1-bands in all derivations and higher coherence (especially in the theta 1, 2 bands most expressed in the frontoparietal areas) as compared with the high-intuition responders. The expression of extraversion was positively correlated with coherence values in the theta 1, 2 and negatively correlated with coherence in the alpha 1, 2 bands. Characteristic EEG patterns for other types of personality traits were also described. The results suggest that some characteristics of brain maps reflect the individual psychological features determined on the basis of Jung's typology. 相似文献
11.
12.
Familial and twin studies have shown that the individual variability of the normal human electroencephalogram (EEG) is largely genetically determined. In epileptology, these genetic parameters of the EEG background activity are almost totally neglected. The aim of the present study has been to investigate whether a special genetic type of background activity might be related to the pathogenesis of epilepsy. EEG recordings of parents of 257 epileptic children were evaluated retrospectively. Some 156 healthy adults served as controls. Special attention was paid to alpha activity extending to the frontal region, both in bipolar and in referential recordings (Alpha I). Alpha I was found significantly more often in parents of children with primary generalized epilepsy (18%) compared with parents of children with focal epilepsy (8%) or controls (9%). In a second step, parental EEGs of children with different EEG patterns associated with epilepsy were studied. Alpha I was found significantly more often in parents of children with focal sharp waves and generalized spikes and waves (26%) than in parents of probands with focal sharp waves without additional generalized spikes and waves (8%) or in controls (9%). Parents of probands with theta rhythms and spikes and waves had alpha I significantly more often (18%) than parents of probands with theta rhythms without additional spikes and waves (8%) or controls (9%). The findings reveal a clear correlation between the type of EEG background activity in parents and the EEG characteristics in their children, thus pointing to common mechanisms. 相似文献
13.
Batuev AS Iovleva NN Koshchavtsev AG 《Rossi?skii fiziologicheski? zhurnal imeni I.M. Sechenova / Rossi?skaia akademiia nauk》2007,93(8):905-913
The research involved comparison of characteristics of the power spectrum, index, coherence of the EEG at preterm and full-term infants of the first month of life. 6 groups of children are surveyed: (1) 30-32, (2) 33-34, (3) 35-36, (4) 37-38, (5) 39-40, (6) 41-42 weeks of gestation; each group consisted of 10 children. Capacity of delta frequencies was high in the 5th group. Capacity of theta frequencies was high in the 3rd group. The index of theta frequencies was high in the 2nd, 3rd and 4th groups. Capacity of alpha frequencies was hagh in the 2nd group. The index of alpha frequencies was high in the 1st, 2nd and 3rd groups. Indexes and of beta1- and beta2-frequencies were higher in the 1st, 2nd and 4th groups. The maximum quantity of coherent delta, theta and alpha frequencies was in the 6th group. In the 2nd group, in comparison with 5th group, were more coherent delta frequencies in the occipital and occipital-central areas. The results obtained show that the spectrum of capacity, indexes and coherence of the EEG depend on term of gestation at the moment of birth but this dependence has nonlinear character. 相似文献
14.
The presentation of two sinusoidal tones, one to each ear, with a slight frequency mismatch yields an auditory illusion of a beating frequency equal to the frequency difference between the two tones; this is known as binaural beat (BB). The effect of brief BB stimulation on scalp EEG is not conclusively demonstrated. Further, no studies have examined the impact of musical training associated with BB stimulation, yet musicians'' brains are often associated with enhanced auditory processing. In this study, we analysed EEG brain responses from two groups, musicians and non-musicians, when stimulated by short presentation (1 min) of binaural beats with beat frequency varying from 1 Hz to 48 Hz. We focused our analysis on alpha and gamma band EEG signals, and they were analysed in terms of spectral power, and functional connectivity as measured by two phase synchrony based measures, phase locking value and phase lag index. Finally, these measures were used to characterize the degree of centrality, segregation and integration of the functional brain network. We found that beat frequencies belonging to alpha band produced the most significant steady-state responses across groups. Further, processing of low frequency (delta, theta, alpha) binaural beats had significant impact on cortical network patterns in the alpha band oscillations. Altogether these results provide a neurophysiological account of cortical responses to BB stimulation at varying frequencies, and demonstrate a modulation of cortico-cortical connectivity in musicians'' brains, and further suggest a kind of neuronal entrainment of a linear and nonlinear relationship to the beating frequencies. 相似文献
15.
Heritability of human brain functioning as assessed by electroencephalography. 总被引:5,自引:1,他引:4
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C. E. van Beijsterveldt P. C. Molenaar E. J. de Geus D. I. Boomsma 《American journal of human genetics》1996,58(3):562-573
To study the genetic and environmental contributions to individual differences in CNS functioning, the electroencephalogram (EEG) was measured in 213 twin pairs age 16 years. EEG was measured in 91 MZ and 122 DZ twins. To quantify sex differences in the genetic architecture, EEG was measured in female and male same-sex twins and in opposite-sex twins. EEG was recorded on 14 scalp positions during quiet resting with eyes closed. Spectral powers were calculated for four frequency bands: delta, theta, alpha, and beta. Twin correlations pointed toward high genetic influences for all these powers and scalp locations. Model fitting confirmed these findings; the largest part of the variance of the EEG is explained by additive genetic factors. The averaged heritabilites for the delta, theta, alpha and beta frequencies was 76%, 89%, 89%, and 86%, respectively. Multivariate analyses suggested that the same genes for EEG alpha rhythm were expressed in different brain areas in the left and right hemisphere. This study shows that brain functioning, as indexed by rhythmic brain-electrical activity, is one of the most heritable characteristics in humans. 相似文献
16.
Previous studies have rarely examined how temporal dynamic patterns, event-related coherence, and phase-locking are related to each other. This study assessed reaction-time-sorted spectral perturbation and event-related spectral perturbation in order to examine the temporal dynamic patterns in the frontal midline (F), central parietal (CP), and occipital (O) regions during a chemistry working memory task at theta, alpha, and beta frequencies. Furthermore, the functional connectivity between F-CP, CP-O, and F-O were assessed by component event-related coherence (ERCoh) and component phase-locking (PL) at different frequency bands. In addition, this study examined whether the temporal dynamic patterns are consistent with the functional connectivity patterns across different frequencies and time courses. Component ERCoh/PL measured the interactions between different independent components decomposed from the scalp EEG, mixtures of time courses of activities arising from different brain, and artifactual sources. The results indicate that the O and CP regions’ temporal dynamic patterns are similar to each other. Furthermore, pronounced component ERCoh/PL patterns were found to exist between the O and CP regions across each stimulus and probe presentation, in both theta and alpha frequencies. The consistent theta component ERCoh/PL between the F and O regions was found at the first stimulus and after probe presentation. These findings demonstrate that temporal dynamic patterns at different regions are in accordance with the functional connectivity patterns. Such coordinated and robust EEG temporal dynamics and component ERCoh/PL patterns suggest that these brain regions’ neurons work together both to induce similar event-related spectral perturbation and to synchronize or desynchronize simultaneously in order to swiftly accomplish a particular goal. The possible mechanisms for such distinct component phase-locking and coherence patterns were also further discussed. 相似文献
17.
Corrine C. J. Kramer Gerard G. A. Kerkhof Winni W. F. Hofman 《Biological Rhythm Research》1998,29(1):105-117
In order to assess age effects upon the daytime level of alertness, both subjective and objective measures of alertness were obtained in 19 healthy elderly males (mean age 65 years) and 19 healthy young males (mean age 21 years). Subjects were recorded during a Multiple Sleep Latency Test (MSLT), administered at 5 different times of day (9 a.m., 12 a.m., 3 p.m., 6 p.m., 9 p.m.). Before each test, subjects filled out an alertness questionnaire. During the entire 20 minutes of each test electroencephalographic (EEG) recordings were made and transformed into 40 averaged spectra, one for each 30 s epoch. For the delta, theta, alpha, sigma and beta bands of the EEG 6 consecutive values were averaged to obtain 1 value per 3 minutes. On the basis of the visually guided detection of the first spindle, sleep onset was determined. The elderly subjects obtained a higher overall level of subjective alertness than the young subjects. No age effect was observed for sleep latency, which followed a U-shaped diurnal trend. Overall, the mean relative EEG energy values followed a diurnal trend that was the reverse of that for sleep latency. The mean relative delta EEG energy gradually increased, and the mean relative alpha EEG energy gradually decreased across the MSLT. For the young subjects the respective ranges of variation of these EEG bands were very similar, while for the elderly subjects the range of variation of the alpha values was less than half of that for the delta band. Apparently, alpha EEG activity during the wake-sleep transition does not simply covary with delta EEG activity. Moreover, age appears to have a significant effect upon the dynamics of alpha EEG activity during the wake-sleep transition. 相似文献
18.
Kaplan AIa Borisov SV Shishkin SL Ermolaev VA 《Rossi?skii fiziologicheski? zhurnal imeni I.M. Sechenova / Rossi?skaia akademiia nauk》2002,88(4):432-442
Phasic organisation of human EEG alpha activity was studied in a pilot investigation using a previously suggested EEG segmental analysis methodology. The EEG was recorded in three normal subjects under resting conditions. The segmentation procedure enabled effective identifying of the periods with different amplitude in alpha band and the short-term transitions between them. Mean intersegmental variability of amplitude envelope were computed for the eyes closed and eyes open EEG in each of 16 standard derivations. Analysis of segment amplitude distributions showed that the difference between the average alpha activity amplitude in these conditions were determined mainly by variations in the number of segments of different amplitude classes and not by a shift of the distribution or by change of its width. Distribution and quartile analysis of mean segment amplitudes provide evidence for possible functional heterogeneity of upper and middle subranges of the amplitude range. 相似文献
19.
The neocortical and hippocampal electrical activities were studied in 8, 15, 22, and 29-day-old rats. Segments of EEG recorded for 4 hours were analyzed by means of fast Fourier transformation. The sleep-wake activity stages were determined. The developments in the neocortical and hippocampal EEG activities were characterized by the gradual appearance of adult-like EEG waves and a shift towards higher frequencies in the theta wave range of the hippocampal electrical activity. The power value in the theta range, however, exhibited age-invariant rhythmicities with cycle lengths of about 9.5-11 and 16-22 min. The manifestation of such an age-invariant rhythm can be interpreted as an electrical manifestation of the rest-activity cycle originally described by KLEITMAN25. 相似文献
20.
K P Westphal B Gr?zinger A Foit V Diekmann B Schwab H H Kornhuber 《Archives italiennes de biologie》1986,124(4):221-228
EEG segments of 1 sec duration, beginning 1 sec before the imperative stimulus were analysed by Fast Fourier Transformation in a CNV paradigm with interstimulus intervals (ISI) of different durations (1, 3, 5 sec) and with constant (K1, K3, K5) and randomized (R1, R3, R5) ISI presentation. In the alpha band, there were found differences in the power spectra between the constant and the longer randomized (R3, R5) ISI conditions, the latter having a slower center frequency, a smaller radius of gyration and a higher kurtosis. This describes a sharper alpha line of slower frequency in the R3 and the R5 ISI condition, due to pronounced synchronisation of alpha activity. It is discussed as an expression of increased relaxation and reduced concentration. In the theta band, differences appeared between the short ISI conditions (K1, R1) and the longer ones. 相似文献