Mutations from patients with IPEX ported to mice reveal different patterns of FoxP3 and Treg dysfunction

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Genetic variation associated with condensate dysregulation in disease

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Overcoming Expressional Drop-outs in Lineage Reconstruction from Single-Cell RNA-Sequencing Data

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Dispersal strategies shape persistence and evolution of human gut bacteria

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Two pup vocalization types are genetically and functionally separable in deer mice

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Genetic structure correlates with ethnolinguistic diversity in eastern and southern Africa

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Functional characterization of 5p15.33 risk locus in uveal melanoma reveals rs452384 as a functional variant and NKX2.4 as an allele-specific interactor

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ELIMÄKI Locus Is Required for Vertical Proprioceptive Response in Birch Trees

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Recording of DNA-binding events reveals the importance of a repurposed Candida albicans regulatory network for gut commensalism

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iTAG-RNA Isolates Cell-Specific Transcriptional Responses to Environmental Stimuli and Identifies an RNA-Based Endocrine Axis

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Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity,Linking PHIP Variants to Repressed POMC Transcription

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High genetic diversity and low differentiation reflect the ecological versatility of the African leopard

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Co-transmission of Related Malaria Parasite Lineages Shapes Within-Host Parasite Diversity

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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

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Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs

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Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience

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Natural Selection Shapes Variation in Genome-wide Recombination Rate in Drosophila pseudoobscura

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The dihydropyrimidine dehydrogenase gene contributes to heritable differences in sleep in mice

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Plant glutamate receptors mediate a bet-hedging strategy between regeneration and defense

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Conserved multi-tissue transcriptomic adaptations to exercise training in humans and mice

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