共查询到20条相似文献,搜索用时 46 毫秒
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H Youssoufian L I Zon S H Orkin A D D''''Andrea H F Lodish 《Molecular and cellular biology》1990,10(7):3675-3682
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Characterization of the mouse rod transducin alpha subunit gene 总被引:6,自引:0,他引:6
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S Avraham K F Austen C F Nicodemus M C Gartner R L Stevens 《The Journal of biological chemistry》1989,264(28):16719-16726
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gamma-Glutamyl transpeptidase: a single copy gene in the rat and a multigene family in the human genome 总被引:5,自引:0,他引:5
A Pawlak O Lahuna F Bulle A Suzuki N Ferry S Siegrist N Chikhi M N Chobert G Guellaen Y Laperche 《The Journal of biological chemistry》1988,263(20):9913-9916
gamma-Glutamyl transpeptidase (GGT) genomic sequences were isolated from rat and human libraries using a rat GGT cDNA as a cross-species hybridization probe. Characterization of the human GGT clones by restriction mapping clearly establishes that at least four different GGT genes or pseudogenes are present in the human genome. All the rat genomic clones cover a 12.5-kilobase sequence and exhibit a unique restriction pattern. A precise quantitation of the rat GGT gene copy number by Southern blot analysis demonstrates that this sequence is present as a single copy/rat haploid genome. Therefore, the GGT gene organization is different between rat and human species; this raises the possibility of different regulatory mechanisms in the two species. 相似文献
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