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Jolanta Szenajch Gabriel Wcislo Jee-Yeong Jeong Cezary Szczylik Laurie Feldman 《生物化学与生物物理学报:癌评论》2010
Recombinant human erythropoietin (rhEPO) has been used clinically to alleviate cancer- and chemotherapy-related anemia. However, recent clinical trials have reported that rhEPO also may adversely impact disease progression and survival. The expression of functional EPO receptors (EPOR) has been demonstrated in many human cancer cells where, at least in vitro, rhEPO can stimulate cell growth and survival and may induce resistance to selected therapies. 相似文献