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An interdisciplinary team performed autopsies on an adult male and an infant male mummy from the American Southwest. Cause of death has not been determined for the infant. The presence of an unhealed skull fracture associated with an apparent hematoma in the adult male is suggestive of trauma as the cause of death in the adult. Evidence of disease is minimal. Analysis of powder thought to be dried blood from the thoracic cavity of the adult suggests the presence of human IgG. The instability of this protein may indicate the presence of proteolytic activity by enzymes that degrade immunoglobulins upon rehydration. The possibility of enzymatic degradation of proteins will be an important factor in future studies of such immunoglobulins in mummy remains and also indicates the importance of maintaining the desiccated condition of mummy tissues.  相似文献   

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Invasive surgical procedures are often used to study the reproductive and adrenocortical endocrine systems in primates. Anesthetic agents must, therefore, be used that have the least confounding effects on these systems. The present study was designed to characterize various adrenocortical endocrine responses of female baboons (Papio anubis), each treated for 120 minutes with an infusion of ketamine HCl (6 mg/min) in 5% dextrose in water (0.40 ml/min), a combination of ketamine and acetylpromazine (0.6 mg acetylpromazine and 6 mg ketamine HCl/min) in 5% dextrose in water, or inhalation of vaporized halothane (1.0% halothane, N2O 25%, 1 liter/min; O2 75%, 3 liters/min). Blood samples were collected throughout the treatment period, and serum was assayed for prolactin (PRL), dehydroepiandrosterone (DHA), dehydroepiandrosterone sulfate (DHAS), and cortisol (F). No significant elevations in DHA, F, or PRL concentrations were found following infusion of ketamine alone. Only serum DHAS concentrations were significantly altered after long-term exposure to ketamine. Acetylpromazine increased PRL concentrations tenfold to levels significantly greater than those in ketamine- and halothane-treated animals but had no effect on serum DHA, DHAS, or F. Treatment with halothane had no effect on serum PRL, DHA, or DHAS but did suppress F (>40%) concentrations over time. These data indicate that ketamine is best suited for the collection of biological samples when deep analgesia is not required but that halothane is preferable in the latter situation.  相似文献   

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