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《Cell cycle (Georgetown, Tex.)》2013,12(14):2722-2730
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《Cell cycle (Georgetown, Tex.)》2013,12(14):2713-2721
Comment on: Bommi P, et al. Cell Cycle 2010; 9:2663-73. 相似文献
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Etchegaray JP Yang X DeBruyne JP Peters AH Weaver DR Jenuwein T Reppert SM 《The Journal of biological chemistry》2006,281(30):21209-21215
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The polycomb group protein Suz12 is required for embryonic stem cell differentiation 总被引：11，自引：0，他引：11 
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下载免费PDF全文 Pasini D Bracken AP Hansen JB Capillo M Helin K 《Molecular and cellular biology》2007,27(10):3769-3779
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The polycomb protein Pc2 is a SUMO E3 总被引：37，自引：0，他引：37
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Cyclin E is a target of WT1 transcriptional repression 总被引：5，自引：0，他引：5
Loeb DM Korz D Katsnelson M Burwell EA Friedman AD Sukumar S 《The Journal of biological chemistry》2002,277(22):19627-19632
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Dehmel F Ciossek T Maier T Weinbrenner S Schmidt B Zoche M Beckers T 《Bioorganic & medicinal chemistry letters》2007,17(17):4746-4752
Inhibition of histone deacetylases class I/II enzymes is a new, promising approach for cancer therapy. In the present study, we disclose a new structural class of HDAC inhibitors with the trithiocarbonate motif. A clear structure-activity-relationship was obtained for the cap-linker motif and the putative Zn(2+) complexing head group. Selected analogs display potent inhibition of HDAC enzymatic activity and a cellular potency comparable to that of suberoylanilide hydroxamic acid (SAHA), recently approved for treatment of patients with advanced cutaneous T-cell lymphoma. 相似文献