The dynamic interplay between a PTK (Kit) and a PTP (Shp2) in hematopoietic stem and progenitor cells

Comment on: Zhu HH, et al. Blood 2011; 117:5350-61 and Chan G, et al. Blood 2011; 117:4253-61.     

Complete Genome Sequence of T4-Like Escherichia coli Bacteriophage HX01

Phage T4 is among the best-characterized biological systems (S. Kanamaru and F. Arisaka, Seikagaku 74:131-135, 2002; E. S. Miller et al., Microbiol. Mol. Biol. Rev. 67:86-156, 2003; W. B. Wood and H. R. Revel, Bacteriol. Rev. 40:847-868, 1976). To date, several genomes of T4-like bacteriophages are available in public databases but without any APEC bacteriophages (H. Jiang et al., Arch. Virol. 156:1489-1492, 2011; L. Kaliniene, V. Klausa, A. Zajanckauskaite, R. Nivinskas, and L. Truncaite, Arch. Virol. 156:1913-1916, 2011; J. H. Kim et al., Vet. Microbiol. 157:164-171, 2012; W. C. Liao et al., J. Virol. 85:6567-6578, 2011). We isolated a bacteriophage from a duck factory, named HX01, that infects avian pathogenic Escherichia coli (APEC). Sequence and morphological analyses revealed that phage HX01 is a T4-like bacteriophage and belongs to the family Myoviridae. Here, we announce the complete genome sequence of phage HX01 and report the results of our analysis.     

Detection of circulating tumor cells in the cerebrospinal fluid: A new frontier

Comment on: Patel AS, et al. Oncotarget 2011; 2:752-760     

Linking hematopoietic regeneration to developmental signaling pathways

Comment on: Trompouki E, et al. Cell 2011; 147:577-89.     

Multiple roles of ELG1 with different interactions determine various cellular processes

Comment on: Parnas O, et al. Cell Cycle 2011; 10:2894-903     

The arresting action of microtubules in cell motility

Comment on: Ganguly A, et al. Oncotarget 2011; 2:368-77.     

A novel signaling pathway in TNFα-induced neutrophil apoptosis

Comment on: Geering B, et al. Blood 2011; 117:5953-62.     

Stuck in a balancing act

Comment on: Lee, et al. Cancer Res 2011; 71:3921-31.     

Glis1, a unique pro-reprogramming factor,may facilitate clinical applications of iPSC technology

Comment on: Maekawa M, et al. Nature 2011; 474:225-9.     

p53 and epithelial-mesenchymal transition: A linking thread between embryogenesis and cancer

Comment on: Rinon A, et al. Development 2011; 138:1827-38.     

Aberrant protein interactions in amyloid disease

Comment on: Olzscha H, et al. Cell 2011; 144:67-78.     

The odd couple: Innate-like B cells and the chemokine scavenger D6

Comment on: Hansell CA, et al. Blood 2011; 117:5413-24.     

(H)if blood stem cells gO2 sleep: What can wake them up?

Comment on: Rehn M, et al. Blood 2011; 118:1534-43.     

Beyond tumor suppression: p53 controls blastocyst implantation

Comment on: Sohr S, et al. Cell Cycle 2011; 10:3758-67.     

Prostaglandin signaling in ciliogenesis during development

Comment on: Tayyari F, et al. Nat Med 2011; 17:1132-5.     

Rad18 emerges as a critical regulator of the Fanconi anemia pathway

Comment on: Palle K, et al. Cell Cycle 2011; 10:1625-38.     

Phosphorylation during mitosis: How many kinases are out there?

Comment on: Rizkallah R, et al. Cell Cycle 2011; 10: 3327-36.     

p53 and tumor surveillance: Killer finds way to recruit assassins

Comment on: Li H, et al. Cell Cycle 2011; 10: 3346-58.     

Flying to a halt

Comment on: Zou S, et al. Cell Cycle 2011; 10: 989-98.     

Beyond immune surveillance: Stat1 limits tumor growth in a cell-autonomous fashion

Comment on: Raven JF, et al. Cell Cycle 2011; 10:794-804.