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A peek into the complex realm of histone phosphorylation 总被引:2,自引:0,他引:2
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What histone code for DNA repair? 总被引:8,自引:0,他引:8
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The genes encoding Arabidopsis ORC subunits are E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cells 总被引:1,自引:0,他引:1 下载免费PDF全文
Diaz-Trivino S del Mar Castellano M de la Paz Sanchez M Ramirez-Parra E Desvoyes B Gutierrez C 《Nucleic acids research》2005,33(17):5404-5414
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《Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms》2023,1866(3):194966
Plants control expression of their genes in a way that involves manipulating the chromatin structural dynamics in order to adapt to environmental changes and carry out developmental processes. Histone modifications like histone methylation are significant epigenetic marks which profoundly and globally modify chromatin, potentially affecting the expression of several genes. Methylation of histones is catalyzed by histone lysine methyltransferases (HKMTs), that features an evolutionary conserved domain known as SET [Su(var)3–9, E(Z), Trithorax]. This methylation is directed at particular lysine (K) residues on H3 or H4 histone. Plant SET domain group (SDG) proteins are categorized into different classes that have been conserved through evolution, and each class have specificity that influences how the chromatin structure operates. The domains discovered in plant SET domain proteins have typically been linked to protein-protein interactions, suggesting that majority of the SDGs function in complexes. Additionally, SDG-mediated histone mark deposition also affects alternative splicing events. In present review, we discussed the diversity of SDGs in plants including their structural properties. Additionally, we have provided comprehensive summary of the functions of the SDG-domain containing proteins in plant developmental processes and response to environmental stimuli have also been highlighted. 相似文献
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