Metabolism meets autophagy

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Establishment of sister chromatid cohesion: The role of the clamp loaders

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Adaptation in a eukaryotic pathway

Comment on: Takeda K, et al. Sci Signal 2012; 5:2     

Messengers made for micro-destruction

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Decreased Mdm2 levels after DNA damage: Antibody masking or protein degradation?

Comment on: Cheng Q, et al. Cell Cycle 2011: 10:1162-6.     

Linking Cdc7 with the replication checkpoint

Comment on: Matsumoto S, et al. Cell Cycle 2010; 9: In press.     

Targeting RSK2 in myeloid leukemia: Right for FLT3 but wrong for BCR-ABL

Comment on: Elf S, et al. Blood 2011; 117:6885-94.     

The oncogenic transcription factor FOXM1 and anticancer therapy

Comment on: Halasi M,et al. PLoS One 2012; 7:e31761.     

Methylation of polyphenols with vicinal hydroxyl groups: A protection pathway increasing organismal lifespan

Comment on: Kunstmann B, et al. Aging 2009; 1:328-334.     

In search of housekeeping pathways that regulate longevity

Comment on: Goldberg AA, et al. Aging 2010; 2:393-414.     

Aging,sarcopenia and store-operated calcium entry

Comment on: Thornton AM, et al. Aging 2011; 3:621-34.     

Neighborly DISCourse: DNA double strand breaks silence transcription

Comment on: Shanbhag NM, et al. Cell 2010; 141:970-81.     

A truncated tRNA synthetase directs a “translational trickle” of gene expression

Comment on: Yao P, et al. Cell 2012; 149:88-100.     

Brain and muscle ARNT-like protein BMAL1 regulates ROS homeostasis and senescence: A possible link to hypoxia-inducible factor-mediated pathway

Comment on: Khapre RV, et al. Cell Cycle 2011; 10:4162–9     

pRb or its cousins

Comment on: Bazarov A, et al. Cell Cycle 2012; 11:1008–1013     

Caveolin-1: Would-be Achilles’ heel of tumor microenvironment?

Comment on: Witkiewicz AK, et al. Cell Cycle 2011; 10:1794-809     

Role of the SMYD3 histone methyltransferase in tumorigenesis

Comment on: Cock-Rada AM, et al. Cancer Res 2011; 72:810-20     

A role of miR-33 for cell cycle progression and cell proliferation

Comment on: Cirera-Salinas D, et al. Cell Cycle 2012; 11:922–33     

Genetic mutants illuminate the roles of RecQ helicases in recombinational repair or response to replicational stress

Comment on: Aggarwal M, et al. Aging; 1:219-33.     

Critical role of mTOR in calcineurin inhibitor-induced renal cancer progression

Comment on: Basu A, et al. PLoS One 2011; 6:e23919