共查询到20条相似文献,搜索用时 15 毫秒
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Villagra A Cruzat F Carvallo L Paredes R Olate J van Wijnen AJ Stein GS Lian JB Stein JL Imbalzano AN Montecino M 《The Journal of biological chemistry》2006,281(32):22695-22706
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Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity 下载免费PDF全文
Sierra J Villagra A Paredes R Cruzat F Gutierrez S Javed A Arriagada G Olate J Imschenetzky M Van Wijnen AJ Lian JB Stein GS Stein JL Montecino M 《Molecular and cellular biology》2003,23(9):3339-3351
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The state of acetylation in H3 and H4 histones and dimethylation in the H3 histone Lys4 residue were examined by chromatin immunoprecipitation (ChIP) at 11 targets in the rat Ig-beta/growth hormone locus. Marked enhancement of the acetylation of histones H3 and H4 and the dimethylation of H3 Lys4 was observed in the chromatin situated close to the promoter of an actively transcribed gene. Chromatin positioned near a cell-type-specific DNase I-hypersensitive site with enhancer activity had the same histone modifications as the active promoter. In one transcribed intron, chromatin with fewer histone modifications was found, and in another transcribed intron, chromatin with markedly enhanced modifications was found. In most cases, no appreciable difference in the acetylation of histones H3 and H4 was found at prominently enhanced targets. However, different acetylation levels of H3 and H4 were found at one target. The targets with enhanced dimethylation of the H3 Lys4 residue coincided with those with prominently enhanced acetylation of histones H3 and H4. 相似文献
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Illumination is necessary and sufficient to induce histone acetylation independent of transcriptional activity at the C4-specific phosphoenolpyruvate carboxylase promoter in maize 下载免费PDF全文
Offermann S Danker T Dreymüller D Kalamajka R Töpsch S Weyand K Peterhänsel C 《Plant physiology》2006,141(3):1078-1088
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