共查询到20条相似文献,搜索用时 15 毫秒
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N K Spurr 《Current opinion in biotechnology》1991,2(6):807-811
Advances are being made at an increasing rate towards an understanding of the role of cellular oncogenes in the normal and transformed cell. This review highlights a number of studies looking at the role of these genes in the carcinogenic process using in vivo and in vitro systems. 相似文献
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Studies of the tetraploid potatoes. 总被引:1,自引:0,他引:1
N. W. SIMMONDS F.L.S. 《Botanical journal of the Linnean Society. Linnean Society of London》1966,59(379):279-288
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Maria O Pulina Elena T Zakharova Alexei V Sokolov Mikhail M Shavlovski Mikhail G Bass Kirill V Solovyov Vladimir N Kokryakov Vadim B Vasilyev 《Biochimie et biologie cellulaire》2002,80(1):35-39
We have previously shown that iron-containing human lactoferrin (LF) purified from breast milk is able to form both in vitro and in vivo a complex with ceruloplasmin (CP), the copper-containing protein of human plasma. Here we present evidence that the CP-LF complex is dissociated by high concentrations of NaCl, CaCl2, or EDTA, or by decreasing the pH to 4.7. In addition, DNA, bacterial lipopolysaccharide, and heparin can displace CP from its complex with LF. Antibodies to either of the two proteins also cause dissociation of the complex. 相似文献
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Ichiro Chibata Tasaburo Kigughi Shun’ichi Yamada 《Bioscience, biotechnology, and biochemistry》2013,77(6):333-336
The synthetic procedures for the preparation of α-keto acid analogue of methionine, α-keto-γ-methylmercaptobutyric acid, were investigated. As a result, the procedure consisting of the ester condensation between methyl β-methylmercaptopropionate and methyl oxalate, and subsequent hydrolysis and decarboxylation was found to be a satisfactory route 相似文献
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E Friedrich H Sinn R Kühnlein R Carubelli 《Virchows Archiv. B, Cell pathology including molecular pathology》1978,29(3):201-209
Xenogeneic and enzyme-treated erythrocytes rapidly home to the rat liver as measured by scintigraphic procedures. Histology and scanning electron microscopy revealed that pronase digested erythrocytes are taken up as whole cells by liver histiocytes. 相似文献
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Studies on ocular microsporidia. 总被引:4,自引:0,他引:4
E S Didier J A Shadduck P J Didier N Millichamp C R Vossbrinck 《The Journal of protozoology》1991,38(6):635-638
Sera from six ocular microsporidiosis patients and eight individuals with no history of microsporidiosis were assayed by enzyme-linked immunosorbent assay (ELISA) and by Western blot immunodetection. Microsporidia used as antigen include Nosema corneum, Encephalitozoon hellem, Encephalitozoon cuniculi, and Nosema algerae. Three AIDS patients with known E. hellem infections displayed ELISA antibody titers to E. hellem ranging from 1:400 to 1:12,800. Two patients with unclassified microsporidial infections displayed highest antibody titers to N. algerae (1:1,600 and 1:3,200), a mosquito microsporidian which, reportedly, cannot infect man. A sixth patient with a known N. corneum infection displayed the same ELISA antibody titer (1:1,600) to all four microsporidia. Western blot patterns also were variable among the patient sera; however, the most intense and complex antibody-binding patterns corresponded with the higher ELISA antibody titers. Sera from eight HIV-seronegative individuals with no history of microsporidiosis reacted variably to the four microsporidia. These results suggest that diagnosis of microsporidiosis may depend upon direct detection of the organisms using species-specific antibodies or molecular probes rather than conventional serology. 相似文献