共查询到20条相似文献,搜索用时 15 毫秒
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Bassuk AG Barton KP Anandappa RT Lu MM Leiden JM 《Molecular medicine (Cambridge, Mass.)》1998,4(6):392-401
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cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1. 总被引:39,自引:19,他引:20 下载免费PDF全文
C B Thompson C Y Wang I C Ho P R Bohjanen B Petryniak C H June S Miesfeldt L Zhang G J Nabel B Karpinski et al. 《Molecular and cellular biology》1992,12(3):1043-1053
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The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1 下载免费PDF全文
Göttgens B Broccardo C Sanchez MJ Deveaux S Murphy G Göthert JR Kotsopoulou E Kinston S Delaney L Piltz S Barton LM Knezevic K Erber WN Begley CG Frampton J Green AR 《Molecular and cellular biology》2004,24(5):1870-1883
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《Gene》1999,227(1):71-77
We have cloned the mouse CRTH2 (chemoattractant receptor-homologous molecule expressed on TH2 cells) gene encoding a putative leukocyte chemoattractant receptor, of which human homologue is expressed selectively in Th2 but not in Th1 clones among T cell clones. The deduced amino-acid sequence of mouse CRTH2 bears 77% identity with its human homologue. Phylogenetic analysis suggested that both mouse and human CRTH2 are closely related to the N-formyl peptide receptor and the C5a receptor among leukocyte chemoattractant receptors. The mouse CRTH2 gene was mapped on chromosome 19c with FISH, where no other genes for leukocyte chemoattractant receptors are mapped. RT–PCR analysis revealed that mouse CRTH2 mRNA is expressed in various cell lineages, including both hematopoietic and non-hematopoietic cell lines. Expression was also observed in liver, lung, kidney, brain, heart, thymus, and spleen. These results suggest that mouse CRTH2 functions in a variety of cells, making the effects of CRTH2 pleiotropic. 相似文献
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Juang YT Tenbrock K Nambiar MP Gourley MF Tsokos GC 《Journal of immunology (Baltimore, Md. : 1950)》2002,169(10):6048-6055
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The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis 下载免费PDF全文
Ransom DG Bahary N Niss K Traver D Burns C Trede NS Paffett-Lugassy N Saganic WJ Lim CA Hersey C Zhou Y Barut BA Lin S Kingsley PD Palis J Orkin SH Zon LI 《PLoS biology》2004,2(8):E237
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