Does Collocation Inform the Impact of Collaboration?

Background

It has been shown that large interdisciplinary teams working across geography are more likely to be impactful. We asked whether the physical proximity of collaborators remained a strong predictor of the scientific impact of their research as measured by citations of the resulting publications.

Methodology/Principal Findings

Articles published by Harvard investigators from 1993 to 2003 with at least two authors were identified in the domain of biomedical science. Each collaboration was geocoded to the precise three-dimensional location of its authors. Physical distances between any two coauthors were calculated and associated with corresponding citations. Relationship between distance of coauthors and citations for four author relationships (first-last, first-middle, last-middle, and middle-middle) were investigated at different spatial scales. At all sizes of collaborations (from two authors to dozens of authors), geographical proximity between first and last author is highly informative of impact at the microscale (i.e. within building) and beyond. The mean citation for first-last author relationship decreased as the distance between them increased in less than one km range as well as in the three categorized ranges (in the same building, same city, or different city). Such a trend was not seen in other three author relationships.

Conclusions/Significance

Despite the positive impact of emerging communication technologies on scientific research, our results provide striking evidence for the role of physical proximity as a predictor of the impact of collaborations.     

Collaboration or Contention? Decentralised Marine Governance in Berau

Conservation of marine space is a new frontier in environmentalists’ involvement with resource governance in Indonesia. The coastal and marine area of Berau was established as a District Marine Conservation Area (MCA) based on District Head Regulation No. 31/2005. The total MCA of 1.27 million ha was expected to become part of the wider MCA networks of the East Borneo Seascape and the Sulu Sulawesi Marine Ecoregion, as well as of the Coral Triangle international network of conservation areas in Southeast Asia and the Pacific. The Berau MCA was developed in collaboration between the Berau district government and international environmental non-governmental organisations (NGOs) such as The Nature Conservancy (TNC) and the World Wide Fund for Nature (WWF). They claimed to use a new concept of partnership with the decentralised district government as the principal institutional partner. However, the governance framework is full of legal disconnects due to decentralisation of resource management, and its implementation faces the real-life challenges of political-economic and historical valuations of the marine environment producing conflicts of interest between the multi-scalar actors involved. Following the very process of establishing the Berau MCA over a five-year period (2005–2010), this paper shows why it is necessary to understand how collaboration and contention are constructed and in turn construct actors' perceptions and perspectives on marine conservation and resource extraction in decentralised coastal governance.     

Working for the Forest: The Ambivalent Intimacies of Human–Elephant Collaboration in South Indian Wildlife Conservation

This paper explores the collaboration of humans and elephants in South Indian wildlife conservation. Drawing on ethnography within the Indian forest department and among elephant handlers in Wayanad, Kerala, it highlights the largely invisible work relationship between indigenous forest labourers and captive elephants, and their essential contribution to wildlife management. Extending ethnographic attention beyond an exclusively human realm, I show that human and elephant relations have been co-constituted while working together for the forest department. Their working partnership, situated in the historical nature-cultures of logging, teak extraction, and conservation, has created ambivalent intimacies between humans and elephants, containing both mutual violence and affect. By highlighting the importance of work relationships, history, and questions of power for multi-species studies, this article argues that human–animal relations are not only shaped by individual intimacies, but also by danger, risk, and aggression, situated within a region's larger political ecology.     

Capitalizing on Synergies—A Discourse Analysis of the Process of Collaboration Among Providers of Integrative Health Care

Background

Integrative health care (IHC) combines therapies and providers from complementary and conventional health care. Previous studies on IHC have shown power relations between providers but few studies have explored how the interaction develops over time. The objective of this study was to explore the development of IHC collaboration and interaction among participating providers during a series of consensus case conferences for managing patients with back and neck pain.

Methods

This qualitative study was conducted within a pragmatic randomized controlled clinical trial in primary care. Patients'' treatment plans were developed based on IHC provider consensus conferences (n = 26) of which 15 (5 of the first, 5 in the middle, and 5 of the last in the clinical trial) were selected for analysis. Findings were derived by means of discourse analysis, focusing on the participants’ use of subject positions during the conferences.

Findings

The IHC team in this study gradually formed a group identity, moving their subject positions from individual treating subjects to members of a team and were able to make consensus-based decisions about patients’ individual treatment plans. In the discourse, the IHC team identified collaborative shortcomings and problematized the provision of IHC. They were able to capitalize on the synergies in their collaboration and developed a shared vision of IHC provision.

Conclusions

The process of IHC collaboration involved the gradual formation of an IHC team identity, which facilitated interdisciplinary, non-hierarchical consensus-based decision-making in the team. The discourse further suggests that a reform of some legal and organizational health sector barriers might be needed to realize sustainable implementation of IHC services in Sweden.     

Physicians' private clinics in a Northern Thai Town — Patient-healer “Collaboration” and the shape of biomedical practice

Physicians' private clinics in small Northern Thai towns offer the patient the services of official biomedicine's most sophisticated clinical talent, and the physicians themselves an opportunity to significantly supplement their incomes. The clinic form, while familiar to Westerners and Japanese, has been adapted to the Northern Thai medical environment and Northern Thai notions of the therapeutic process. Because of sociocultural constraints and the pressure of the plural medical environment, physicians' private clinics result in a collaboration between patient and practitioner in which some prerogatives of each are compromised and others upheld to shape a clinical institution that satisfies the needs of each. This paper discusses three private clinics in a small Northern Thai town from the perspectives of the physicians and the patients, and then describes the collaboration that shapes practices within the clinics.     

Shaping T Cell – B Cell Collaboration in the Response to Human Immunodeficiency Virus Type 1 Envelope Glycoprotein gp120 by Peptide Priming

Prime-boost vaccination regimes have shown promise for obtaining protective immunity to HIV. Poorly understood mechanisms of cellular immunity could be responsible for improved humoral responses. Although CD4+ T-cell help promotes B-cell development, the relationship of CD4+ T-cell specificity to antibody specificity has not been systematically investigated. Here, protein and peptide-specific immune responses to HIV-1 gp120 were characterized in groups of ten mucosally immunized BALB/c mice. Protein and peptide reactivity of serum antibody was tested for correlation with cytokine secretion by splenocytes restimulated with individual gp120 peptides. Antibody titer for gp120 correlated poorly with the peptide-stimulated T-cell response. In contrast, titers for conformational epitopes, measured as crossreactivity or CD4-blocking, correlated with average interleukin-2 and interleukin-5 production in response to gp120 peptides. Antibodies specific for conformational epitopes and individual gp120 peptides typically correlated with T-cell responses to several peptides. In order to modify the specificity of immune responses, animals were primed with a gp120 peptide prior to immunization with protein. Priming induced distinct peptide-specific correlations of antibodies and T-cells. The majority of correlated antibodies were specific for the primed peptides or other peptides nearby in the gp120 sequence. These studies suggest that the dominant B-cell subsets recruit the dominant T-cell subsets and that T-B collaborations can be shaped by epitope-specific priming.