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The radioiodine administration is a standard therapeutic approach to both benign thyroid diseases, such as hyperthyroidism, and carcinomas. The high administered 131I activities are of radiation protection concern, due to relevant patient residual contamination. The aim of this work was to develop a new procedure based on external radiometric surveys and on a mathematical model in order to estimate the 131I activity in patients undergoing hyperthyroidism radioiodine therapy.In the first stage of this study, a suitable detector was chosen and its response vs. activity was characterized. The experimental verification was performed measuring the ambient dose equivalent rate from patients receiving radioiodine administration. The results confirm the reliability of the proposed method, as shown by the slight differences between the administered activities and the ones calculated from external measurements. Furthermore, the same procedure was applied to detect the percentage residual activity in patients at two preset time intervals: 4 hours and 4 days after the radioiodine administration. The obtained results clearly highlight that the method can ensure a level of reliability compatible with the radiation protection purposes. 相似文献
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G. M. Goulko V. V. Chumak N. I. Chepurny K. Henrichs P. Jacob I. A. Kairo I. A. Likhtarev V. S. Repin B. G. Sobolev G. Voigt 《Radiation and environmental biophysics》1996,35(2):81-87
The thyroid doses of 49 360 inhabitants of Pripjat evacuated after the accident at Chernobyl were reconstructed. During
their evacuation most of the evacuees passed through highly contaminated territories. The evaluation of a large-scale public
survey showed that only about 50% of the evacuees had left the contaminated areas within 5 days and that 30% of them stayed
there for more than 30 days. As a first step, the model of dose estimations was improved, and thyroid doses were assessed
for the group of evacuees for whom the 131I activity in the thyroids was measured. The 131I incorporation during the first 5 days after the accident was described by a single-intake model (inhalation); later incorporations
were assumed to be proportional to the radioiodine activity in milk. As a second step, the correlation between the calculated
doses and individual parameters (place of residence in Pripjat, intake of stable iodine, and age at the time of the accident) was described by
an empirical equation. This equation was applied to all evacuees who completed the questionnaires of the public survey. Previous
dose assessments were found to overestimate the thyroid doses especially for the younger evacuees. On the basis of these estimations,
collective doses and the resulting radiation risks for thyroid cancer were assessed for different age groups.
Received: 28 November 1995 / Accepted in revised form: 6 March 1996 相似文献
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