A top-down view on DNA replication and recombination from 9,000 feet above sea level

A report of the Keystone Symposium 'DNA Replication and Recombination' held in Keystone, USA, 27 February to 4 March 2011.     

Assembling a jigsaw puzzle with 20,000 parts

A report on the Keystone Symposium 'Proteomics: Technologies and Applications', Keystone, USA, 25-30 March 2003.     

Plant immunity from A to Z

A report of The Keystone Symposium on Plant Innate Immunity, Keystone, USA, 10-15 February 2008.     

Systems biology: where it's at in 2005

A report on the joint Keystone Symposia on Systems and Biology and Proteomics and Bioinformatics, Keystone, USA, 8-13 April 2005.     

Apoptosis hots up from the cold

The Keystone Symposium on Molecular Mechanisms of Apoptosis was held on 16–22 January 2001 in Keystone, Colorado, USA.     

Signaling in development

A report on the 'Integration of Signaling Pathways in Development' Keystone Symposium, Keystone, Colorado, USA, 27 January to 1 February 2001.     

Epigenomics and chromatin dynamics

A report of the 'Joint Keystone Symposium on Epigenomics and Chromatin Dynamics', Keystone, Colorado, 17-22 January 2012.     

Complex responses to a diverse environment

A report on the Keystone Symposium 'Innate Immunity: Signaling Mechanisms', Keystone, USA, 24-29 February, 2008.     

Systems biology: where it's at in 2005

A report on the joint Keystone Symposia on Systems and Biology and Proteomics and Bioinformatics, Keystone, USA, 8-13 April 2005.     

DNA methylation and epigenomics: new technologies and emerging concepts

A report of the Keystone Symposia joint meetings on DNA Methylation and Epigenomics held in Keystone, Colorado, USA, 29 March to 3 April, 2015.     

Stem cells and their niche: an inseparable relationship

A recent Keystone symposium on 'Stem Cell Interactions with their Microenvironmental Niche' was organized by David T. Scadden and Allan C. Spradling. The meeting was held in conjunction with another Keystone symposium, 'Stem Cells and Cancer', at Keystone, Colorado. Among the work that was presented at this meeting, scientists presented data that advances our understanding of the contribution that the niche makes to stem cell maintenance. Novel types of stem cells and niches were also reported and new findings that clarify our understanding of the molecular mechanisms that regulate and maintain stem cells were presented.     

Keystone Symposia on Epigenomics and Chromatin Dynamics: Keystone resort,CO, January 17–22, 2012

Keystone Symposia kicked off the start of 2012 with two joint meetings on Epigenomics and Chromatin Dynamics and a star-studded list of speakers. Held in Keystone, CO, January 17–22, and organized by Steven Jacobsen and Steven Henikoff and by Bradley Cairns and Geneviève Almouzni, respectively, there was plenty happening in these sessions that it did not seem to matter that the ski-slope conditions were not ideal.     

Keystone Symposia on Epigenomics and Chromatin Dynamics: Keystone resort,CO, January 17–22, 2012

Keystone Symposia kicked off the start of 2012 with two joint meetings on Epigenomics and Chromatin Dynamics and a star-studded list of speakers. Held in Keystone, CO, January 17–22, and organized by Steven Jacobsen and Steven Henikoff and by Bradley Cairns and Geneviève Almouzni, respectively, there was plenty happening in these sessions that it did not seem to matter that the ski-slope conditions were not ideal.     

Host Plant Resistance as an Alternative to Methyl Bromide for Managing Meloidogyne incognita in Pepper

Pre-plant soil fumigation with methyl bromide and host resistance were compared for managing the southern root-knot nematode (Meloidogyne incognita) in pepper. Three pepper cultivars (Carolina Cayenne, Keystone Resistant Giant, and California Wonder) that differed in resistance to M. incognita were grown in field plots that had been fumigated with methyl bromide (98% CH₃Br : 2% CCl₃NO₂ [w/w]) before planting or left untreated. Carolina Cayenne is a well-adapted cayenne-type pepper that is highly resistant to M. incognita. The bell-type peppers Keystone Resistant Giant and California Wonder are intermediate to susceptible and susceptible, respectively. None of the cultivars exhibited root galling in the methyl bromide fumigated plots and nematode reproduction was minimal (<250 eggs/g fresh root), indicating that the fumigation treatment was highly effective in controlling M. incognita. Root galling of Carolina Cayenne and nematode reproduction were minimal, and fruit yields were not reduced in the untreated plots. The root-galling reaction for Keystone Resistant Giant was intermediate (gall index = 2.9, on a scale of 1 to 5), and nematode reproduction was moderately high. However, yields of Keystone Resistant Giant were not reduced in untreated plots. Root galling was severe (gall index = 4.3) on susceptible California Wonder, nematode reproduction was high, and fruit yields were reduced (P ≤ 0.05) in untreated plots. The resistance exhibited by Carolina Cayenne and Keystone Resistant Giant provides an alternative to methyl bromide for reducing yield losses by southern root-knot nematodes in pepper. The high level of resistance of Carolina Cayenne also suppresses population densities of M. incognita.     

Discovering the seeds of diversity in plant genomes

A report on the Keystone Symposium 'Comparative Genomics of Plants', Taos, USA, 4-9 March 2004.     

Probing the cancer genome

A report on the Keystone Symposium 'Cancer Genomics and Epigenomics', Taos, USA, 19-24 February 2008.     

Signals and systems

A report on the 2006 Keystone Conference on Signaling Networks, Vancouver, Canada, 30 January-4 February 2006.     

A burst of energy in metabolic disease research

A report on the 'Diabetes Mellitus' and 'Adipogenesis and Obesity' joint Keystone Symposia, Banff, Canada, 4-10 March 2004.     

Meeting the challenges of drug discovery: a multidisciplinary re-evaluation of current practices

A report on the Keystone Symposium 'Meeting the Challenges of Drug Discovery', Vancouver, Canada, 15-19 January 2005.     

Survival strategies for transposons and genomes

A report on the Keystone Symposium "Transposition and other genome rearrangements", Santa Fe, USA, 8-14 February 2003.