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中医天人相应观是中医学的指导思想,贯穿中医学体系始终,体现了中医学的生态学理念。微生态学作为一门新兴的学科,属于生态医学的范畴,尤其是近年对微生态学的深入研究,发现其研究结果与中医学观点存在共同之处,并已有学者论证二者在理论和实践上都具有一定的统一性,为中医药现代化提供了一定的理论依据。本文回顾性分析了中医天人相应学说和微生态学内容,发现二者在理论起源、发病机制、防治和应用方面具有一定的统一性,并且创新性地从微生态学角度解读中医天人相应学说,从而论证中医学说的正确性和现实性,也为中西医的进一步融合提供新的思路。 相似文献
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中医研究院医史文献研究室 《生物化学与生物物理进展》1974,1(3):27-29
经络学说是祖国医学宝库的重要组成部分。它在中医基础理论和临床的各个方面都得到广泛的应用,在创造我国新医学新药学的过程中,也占有一定的位置。几年来,在毛主席哲学思想的光辉指引下,革命医务人员应用祖国医学的经络学说,大搞中西医结合工作,创造了针刺麻醉,这是医学史上的一件大事。因此,探 相似文献
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现代生物医学科技前沿与中西医结合交叉 总被引:1,自引:0,他引:1
本文讨论了中医现代化和中西医结合的有关问题,指出中医现代化工作可分为三个方面:第一方面,应当培养大批临床上过硬的中医人才,在临床上有所突破,以此为基础进行理论研究;第二方面,将中医理论转换成现代语言;第三方面,中医与包括现代生物医学在内的多学科结合。阐述了现代生物医学科技前沿与中西医结合交叉而产生的新学科一光子中医学。指出光子中医学将为中西医结合提供理论和技术平台,成为多学科研究中医的代表性学科,并将成为中医现代化的一个重要方向,为人类卫生事业作出重大贡献。 相似文献
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在19世纪的下半期,在西欧形成了魏斯曼的种质学说。这个学说在达尔文学说的基础上对遗传和进化提出了一些新的看法,于是出现了新达尔文主义。魏斯曼的种质学说对生物学,特别是对遗传学、胚胎学和进化论有很大的影响。所以这些学科都要谈到这个学说。但是,不同的学派和不同的学者,对这个学说有截然不同的评价。例如,摩尔根学派一般以积极的态度对待这个学说,认为这个学说促进了生物学的发展。有些学者甚至相当全面地接受这个学说。米丘林学派一般采取相反的态度,认为这个学说对生物学的发展没有积极的作用。有些学者甚至认为这个学说是反达尔文主义的,是形而上学的,唯心的,反动的。有些实验胚胎学家对这个学说又另有不同的看法。 相似文献
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目的:研究中西医结合治疗糖尿病足的临床疗效.方法:将146例糖尿病足患者按已接受的治疗方法分为中西医结合治疗组43例和中医药组49例和西医治疗组54例.西医组患者在降血糖的基础上给予营养神经、抗凝、扩张血管、改善微循环、抗感染等治疗,中西医治疗组在此基础上加用中医辨证施治.中医药组则辨证施治内服外用中药.结果:三种疗法疗效对比临床症状改善时间(d)中西医结合治疗组与其他组比较差异有显著性(P<0.05).三组治疗后空腹血糖,糖化血红蛋白水平均有改善,其中西医组比中医组明显(P<0.05).但中西医结合治疗组与其他组比较疗效更佳,统计学有显著性差异(P<0.05).结论:中西医结合组治疗糖尿病足的疗效更好. 相似文献
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《生物化学与生物物理进展》2017,(8)
肿瘤的发生和发展包括了一系列复杂的生物学过程,其中与免疫系统的相互抗衡,直接决定了这场健康保卫战的成败.由"种子与土壤"学说展开的肿瘤微环境的研究,为解开肿瘤形成与侵袭转移之谜提供了新视角,为肿瘤免疫治疗的临床应用提供了理论依据.本文综述了肿瘤微环境的主要成分及其介导的免疫耐受,及肿瘤免疫治疗的研究现状. 相似文献
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摩尔根(Morgan)是现代生物学史上一位杰出的遗传学家和胚胎学家.他因发现了“在果蝇中的遗传传递机理”,创立了基因学说而荣获1933年度医学及生理学诺贝尔奖.他在胚胎学和遗传学研究中大力提倡应用实验方法,对于生物学从单纯形态描述过渡到重视实验和定量分析,使生物学日益成为一门精密的科学,起了重大的作用.他在学术上的民主作风和卓越的组织才能,造就了一大批生物学家,促进了生物科学,特别是遗传学迅速向前发展.正如 相似文献
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Hampton JR 《Perspectives in biology and medicine》2002,45(4):549-568
The freedom of a doctor to treat an individual patient in the way he believes best has been markedly limited by the concept of evidence-based medicine. Clearly all would wish to practice according to the best available evidence, but it has become accepted that "evidence-based" means that which is derived from randomized, and preferably double-blind, clinical trials. The history of clinical trial development, which can be traced to the use of oranges and lemons for the treatment of scurvy in 1747, has reflected a progressive need to establish whether smaller and smaller effects of treatment are real. It has led to difficult concepts such as "equivalence" and aberrations such as "meta-analysis." An examination of evidence-based practice shows that it has usually been filtered through the opinions of experts and journal editors, and "opinion-based medicine" would be a more appropriate term. In the real world of individual patients with multiple diseases who are receiving a number of different drugs, the practice of evidence-based (or even opinion-based) medicine is extremely difficult. For each patient a judgment has to be made by the clinician of the likely balance of risks and benefits of any therapy. Good practice still requires clinical freedom for doctors. 相似文献
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Kumar D 《Genomic Medicine》2007,1(3-4):95-104
The concept of ‘evidence-based medicine’ dates back to mid-19th century or even earlier. It remains pivotal in planning, funding
and in delivering the health care. Clinicians, public health practitioners, health commissioners/purchasers, health planners,
politicians and public seek formal ‘evidence’ in approving any form of health care provision. Essentially ‘evidence-based
medicine’ aims at the conscientious, explicit and judicious use of the current best evidence in making decisions about the
care of individual patients. It is in fact the ‘personalised medicine’ in practice. Since the completion of the human genome
project and the rapid accumulation of huge amount of data, scientists and physicians alike are excited on the prospect of
‘personalised health care’ based on individual’s genotype and phenotype. The first decade of the new millennium now witnesses
the transition from ‘evidence-based medicine’ to the ‘genomic medicine’. The practice of medicine, including health promotion
and prevention of disease, stands now at a wide-open road as the scientific and medical community embraces itself with the
rapidly expanding and revolutionising field of genomic medicine. This article reviews the rapid transformation of modern medicine
from the ‘evidence-based medicine’ to ‘genomic medicine’. 相似文献
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《BMJ (Clinical research ed.)》1999,319(7222):1422
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Okuda H 《Experimental biology and medicine (Maywood, N.J.)》2003,228(10):1250-1255
As a biochemist, I have been studying lipolytic and lipogenic pathways in fat cells since 1963. In 1966, I proposed a hormone-sensitive substrate theory in which catecholamines might not act on lipase but on substrate during their lipolytic processes. The lipolytic and lipogenic pathways are negative and positive processes in triglyceride content of fat cells. Insulin inhibits the negative process (lipolysis) and stimulates the positive process (lipogenesis from glucose). On the other hand, catecholamine stimulates the negative process and inhibits the positive one. These hormones discriminate the negative and positive rules and regulate opposite ways. We tried to find these hormone-like substances in various natural products. We isolated tea saponins, chitosan, and others as insulin-like substances and dimethyl-xanthine as a catecholamine-like one. It is well known that extracellular fluid pH changes from 7.4 to 6.8. Reduction of the pH from 7.4 causes insulin resistance. Insulin failed to stimulate glucose uptake at pH 7.0 of the extracellular fluid. We found minus ions, which stimulated lipogenesis from glucose by raising extracellular fluid pH to 7.4. These are our approaches to find functional substances that prevent lifestyle-related diseases. 相似文献
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Mutsuhiro Nakao 《BioPsychoSocial medicine》2010,4(1):19
This article introduces key concepts of work-related stress relevant to the clinical and research fields of psychosomatic
medicine. Stress is a term used to describe the body's physiological and/or psychological reaction to circumstances that require
behavioral adjustment. According to the Japanese National Survey of Health, the most frequent stressors are work-related problems,
followed by health-related and then financial problems. Conceptually, work-related stress includes a variety of conditions,
such as overwork, unemployment or job insecurity, and lack of work-family balance. Job stress has been linked to a range of
adverse physical and mental health outcomes, such as cardiovascular disease, insomnia, depression, and anxiety. Stressful
working conditions can also impact employee well-being indirectly by directly contributing to negative health behaviors or
by limiting an individual's ability to make positive changes to lifestyle behaviors, such as smoking and sedentary behavior.
Over the past two decades, two major job stress models have dominated the occupational health literature: the job demand-control-support
model and the effort-reward imbalance model. In both models, standardized questionnaires have been developed and frequently
used to assess job stress. Unemployment has also been reported to be associated with increased mortality and morbidity, such
as by cardiovascular disease, stroke, and suicide. During the past two decades, a trend toward more flexible labor markets
has emerged in the private and public sectors of developed countries, and temporary employment arrangements have increased.
Temporary workers often complain that they are more productive but receive less compensation than permanent workers. A significant
body of research reveals that temporary workers have reported chronic work-related stress for years. The Japanese government
has urged all employers to implement four approaches to comprehensive mind/body health care for stress management in the workplace:
focusing on individuals, utilizing supervisory lines, enlisting company health care staff, and referring to medical resources
outside the company. Good communications between occupational health practitioners and physicians in charge in hospitals/clinics
help employees with psychosomatic distress to return to work, and it is critical for psychosomatic practitioners and researchers
to understand the basic ideas of work-related stress from the viewpoint of occupational health. 相似文献
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An important by-product of sequencing the human genome has been the development of a novel 'toolbox' for biomarker discovery and development. Genomic medicine is an emerging discipline in the genome sciences that integrates these tools to interrogate genomic variation in well-defined populations in order to develop predictors of disease susceptibility, progression and drug response. Several important classes of biomarkers result from these analyses which, when translated to clinical medicine and drug development, will have an important impact on human health and disease. This review highlights both the opportunities and challenges in bringing biomarkers into clinical medicine. 相似文献