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Sck1, a High Copy Number Suppressor of Defects in the Camp-Dependent Protein Kinase Pathway in Fission Yeast, Encodes a Protein Homologous to the Saccharomyces Cerevisiae Sch9 Kinase 总被引:1,自引:0,他引:1
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M. Jin M. Fujita B. M. Culley E. Apolinario M. Yamamoto K. Maundrell C. S. Hoffman 《Genetics》1995,140(2):457-467
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Schizosaccharomyces pombe Git7p,a member of the Saccharomyces cerevisiae Sgtlp family,is required for glucose and cyclic AMP signaling,cell wall integrity,and septation
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Schadick K Fourcade HM Boumenot P Seitz JJ Morrell JL Chang L Gould KL Partridge JF Allshire RC Kitagawa K Hieter P Hoffman CS 《Eukaryotic cell》2002,1(4):558-567
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Recent studies have shown that global gene expression during oxidative stress in Schizosaccharomyces pombe is regulated by stress-induced activation and binding of Csx1 to atf1(+) mRNA. However, the kinase responsible for the activation of Csx1 has not been identified. Here, we describe, for the first time, that Csx1 is phosphorylated by S. pombe LAMMER kinase, Lkh1, under oxidative conditions and that the stress-activated binding of the Csx1 to the atf1(+) mRNA was also affected by Lkh1 and Spc1. These data indicate that concerted actions of Spc1 and Lkh1 are required for the activation of Csx1 during oxidative condition in the fission yeast S. pombe. 相似文献