共查询到20条相似文献,搜索用时 31 毫秒
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Independently evolving chicken histone H2B genes: identification of a ubiquitous H2B-specific 5'' element. 总被引:42,自引:18,他引:24
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The DNA sequence of two chicken histone H2B genes has been determined. Both genes code for the same H2B subtype. Except for conserved "promoter" elements, the sequences 5' to the protein coding regions are completely divergent, indicating that the genes are distantly related and are not evolving in concert. This presents an ideal situation for sequence comparisons. We have discovered a 13 bp, H2B specific homology block, 5' CTCATTTGCATAC 3' located close to the "TATA box". This motif is conserved in all H2B gene leader regions so far sequenced. One of the H2B genes is closely linked, in a divergent arrangement, to an H2A gene, and sequence data suggests that the linked genes share promoter elements. 相似文献
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Comparison of two yeast invertase genes: conservation of the upstream regulatory region. 总被引:12,自引:1,他引:11
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The yeast genome contains a dispersed family of invertase structural genes (SUC1-SUC5, SUC7). Five of these genes are located very close to telomeres and are flanked by large regions of homologous sequence; recombination between telomeres could account for the dispersal of these SUC genes to different chromosomes. The SUC2 locus, in contrast, is not near a telomere and does not share large regions of flanking homology with the other loci. We examine here the relationship between SUC2 and one of the telomeric genes, SUC7. Sequence comparison revealed homology extending from about position -624 to +1791, which is close to the end of the mRNA. The 5' noncoding sequence includes two highly conserved regions: the region between -140 and +1, which contains the TATA box and presumably other promoter elements, and a second region extending from -508 to -400, which corresponds to the upstream regulatory region. 相似文献
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The Epstein-Barr virus (EBV) early promoter DR contains a cis-acting element responsive to the EBV transactivator EB1 and an enhancer with constitutive and inducible activities. 总被引:4,自引:15,他引:4
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P Chavrier H Gruffat A Chevallier-Greco M Buisson A Sergeant 《Journal of virology》1989,63(2):607-614
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Novel cis-acting elements in petunia Cab gene promoters 总被引:19,自引:0,他引:19
David Gidoni Paul Brosio Diane Bond-Nutter John Bedbrook Pamela Dunsmuir 《Molecular & general genetics : MGG》1989,215(2):337-344
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