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《Journal of molecular biology》2019,431(14):2487-2492
Microbes are often thought of as individual cells. However, in their natural habitats, they typically exist in the context of other cells, be they of the same or different species. How these cells interact in space and time is key to their ecology and evolution. In this perspective, we consider the implications of this in terms of the future of microbiological research.This article is part of the special issue "Microbiology: how to bridge mechanisms and phenomenology" edited by Suckjoon Jun.  相似文献   

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The average travelling speed increases in a nontrivial manner with the travel distance. This leads to scaling-like relations on quite extended spatial scales, for all mobility modes taken together and also for a given mobility mode in part. We offer a wide range of experimental results, investigating and quantifying this universal effect and its measurable causes. The increasing travelling speed with the travel distance arises from the combined effects of: choosing the most appropriate travelling mode; the structure of the travel networks; the travel times lost in the main hubs, starting or target cities; and the speed limit of roads and vehicles.  相似文献   

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How life on Earth began remains an unexplained scientific problem. This problem is nuanced in its practical details and the way attempted explanations feedback with questions and developments in other areas of science, including astronomy, biology, and planetary science. Prebiotic chemistry attempts to address this issue theoretically, experimentally, and observationally. The ease of formation of bioorganic compounds under plausible prebiotic conditions suggests that these molecules were present in the primitive terrestrial environment. In addition to synthesis in the Earth's primordial atmosphere and oceans, it is likely that the infall of comets, meteorites, and interplanetary dust particles, as well as submarine hydrothermal vent synthesis, may have contributed to prebiotic organic evolution. The primordial organic soup may have been quite complex, but it did not likely include all of the compounds found in modern organisms. Regardless of their origin, organic compounds would need to be concentrated and complexified by environmental mechanisms. While this review is by no means exhaustive, many of the issues central to the state of the art of prebiotic chemistry are reviewed here.  相似文献   

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We are family     
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We are devo-evo     
Workshop: Novartis Foundation Symposium No. 222: Homology, London, UK, 21–23 July 1998. Followed by an Open Meeting: Homology, Welcome Trust, London, UK, 24 July 1998.  相似文献   

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