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Jiménez-Alonso B 《Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences》2008,39(2):247-254
This study focuses on eugenics in Spain, and more specifically on the 'official' eugenics whose platform was the Primeras Jornadas Eugénicas Espa?olas (First Spanish Eugenic Days, FSED). The aim of this paper is to relate eugenics to 'governmentality' rather than to State politics alone and to 'Latin eugenics' rather than to 'mainline eugenics'. On the one hand, the FSED were largely centred on the development of a new sexual code which would set Catholic sexual morality aside. For this reason, sexual pedagogy was one of the most relevant topics during the FSED, personal responsibility becoming the first step to social change. The concern about making people play an active role in their own self-regulation is typical of governmentality. The latter refers to societies where power is decentered and where the objective is to structure the field of action of others (the conduct of conduct). On the other hand, the FSED emphasised preventive eugenics such as welfare programmes and health campaigns rather than negative eugenics such as the sterilisation of the unfit. The situation in Spain was mirrored in countries such as Brazil, Argentina and Mexico, which allows us to think about them in terms of 'Latin eugenics' rather than 'mainline eugenics' from countries such as Great Britain, Germany and the USA. 相似文献
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K-Cl cotransport is abnormally active in erythrocytes containing positively charged hemoglobins such as Hb S (SS: β6 Glu → Val) or Hb C (CC: β6 Glu → Lys). The relatively younger age of erythrocytes in these diseases cannot completely account for the increased K-Cl cotransport activity. It has been suggested that these positively charged Hb may interact with the K-Cl cotransport system or one of its regulators and induce changes in its functional activity. We report here data on the volume- and pH-dependence of K-Cl cotransport in ghosts obtained from normal and sickle erythrocytes, and on the effect of addition of either Hb A or Hb S before resealing. In erythrocyte ghosts prepared with the gel column method to contain minimal amounts of Hb, (white ghosts, WG), K-Cl cotransport has similar magnitude in normal and sickle erythrocytes, is not inhibited by alkaline pH and it is volume-independent. Addition of low concentrations of Hb A to WG from normal erythrocytes decreases the magnitude of K-Cl cotransport and restores its volume dependency, but not its pH sensitivity. Addition of Hb S to WG from either normal or sickle erythrocytes restores the volume-dependent component of K-Cl cotransport and increases the magnitude of flux mediated by this transporter. Thus, Hb A and Hb S seem to affect in different manners the functional properties of K-Cl cotransport. Received: 29 May 1998/Revised: 3 November 1998 相似文献
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Humans alone among primates lack a superficial head of the temporalis muscle, although a complete superficial muscle is present in 1% of humans and an incomplete one in 8%. Yet the temporal fascia of normal humans contains all the fascial sheets associated with that head even though it is absent. The implication is that humans have lost the superficial temporal muscle, that this is evident from the retention of the fascial sheets, and that the muscular variations represent situations where the muscle has persisted to some degree. Molecular factors in the head domain that are responsible for the development of the muscles of mastication (myosin heavy chain 16) are likewise different in humans than in all non-human species and seem to be responsible for the reduction of those muscles in humans. Could the loss of the superficial portion of the temporalis muscle be a component of this reduction? Could the uncommon muscular variations result from some slight persistence of the prior molecular situation? Could the persistence of the fascial sheets, even when the muscle is absent, be because the molecular factors responsible for connective tissues are not the same as those responsible for muscles? How much of all this can be visualised in the fossil record? Skeletal dimensions of the temporal fossa, partly related to the temporal muscle size, imply that it may be possible to determine in which fossils temporal muscle reduction has occurred. Likewise, surface features of the bone in modern humans without a superficial muscular component but with a strong complex fibrous element suggest that it might be possible to determine, in any fossil in which the surface preservation is good enough, how far back this situation may have persisted. It is already known that myosin heavy chain molecular dating suggests that the muscle reduction may have occurred about 2.4 million years ago. 相似文献
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Many forelimb muscles (e.g. coracobrachialis, rhomboids, serratus sheet) are much less complex and much smaller in humans than in other primates. Yet human muscular variations and persistent fascial sheets indicate that increased size and complexity were once the norm. These muscular reductions are associated with equivalent skeletal gracilisation. Is it possible that molecular phenomena, not unlike those producing reduction of the jaw muscles and associated with gracilisation of the skull in species with reduced need for powerful mastication, may also have reduced forelimb muscles with gracilisation of its skeleton in species no longer using a forelimb for powerful locomotion? Could such molecular and skeletal changes be dated (as for the masticatory muscles) thus giving the time of origination of prehuman forelimb reduction and true bipedalism? 相似文献
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Bhyravabhotla Jayaram 《Journal of molecular evolution》1997,45(6):704-705
A reexamination of the genetic code suggests a rule of conjugates which captures the observed quartet degeneracies without
exception. Adenine is the conjugate of cytosine and uracil is the conjugate of guanine. Further analysis reveals that the rule of conjugates is a macrolevel manifestation of the molecular-level hydrogen-bonding
and base-stacking interactions at the decoding site. This new perspective is of significance to evolutionary discussions of
nucleic acid bases, genetic code, and interactions involving RNAs.
Received: 29 November 1996 / Accepted: 8 June 1997 相似文献
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Nils Bubandt 《Ethnos》2013,78(1):48-80
Recent years have witnessed an increasing number of calls for anthropology to devote more attention to non‐visual modes of perception. Frequently, the implicit suggestion of these calls has been that the acknowledgement of different ways of organising the senses could help us escape the supposed malaise of modern ‘ocular‐centrism ‘. This paper explores the sense and symbolism of smell in Buli, a village in eastern Indonesia, to argue that smell is part of an ontology that catches Buli people in a malaise of their own. ‘Bad’ smell attests to an ambiguous moral order that can be traced across myth, ritual and everyday life. Ambiguity is ever‐present because ‘bad’ or disgusting smells destabilise the very conceptual order they also help support. The analysis of smells as they relate to local notions of disgust is therefore suggested as an alternative way to conceptualise the contradictory nature of power. 相似文献
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Nancy Scheper-Hughes 《American anthropologist》2003,105(1):172-174
Scarce Goods: Justice, Fairness, and Organ Transplantation. Thomas Koch. Westport, CT: Praeger, 2002. 250 pp.
The Twice Dead: Organ Transplants and the Reinvention of Death. Margaret Lock Berkeley: University of California Press, 2002. 429 pp. 相似文献
The Twice Dead: Organ Transplants and the Reinvention of Death. Margaret Lock Berkeley: University of California Press, 2002. 429 pp. 相似文献
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Ricardo Godoy Christopher P. A. Bennett 《Human ecology: an interdisciplinary journal》1991,19(1):83-98
This article contains a comparison of the profits of cultivating modern and traditional varieties of coconuts as a monocrop and as an intercrop, in ideal and in average growing conditions, with good and with average management. We carry out the analysis from a private (financial) and from a national (economic) perspective. The results show that intercropping generates more income than monocropping. In the conclusion we discuss why development organizations and Third World countries encourage monocropping. 相似文献
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Bullen JJ Rogers HJ Spalding PB Ward CG 《FEMS immunology and medical microbiology》2005,43(3):325-330
Bacterial resistance to antibiotics is a major threat to clinical medicine. However, natural resistance to bacterial infection, which does not depend on antibiotics, is a powerful protective mechanism common to all mankind. The availability of iron is the heart of the matter and the successful functioning of these antibacterial systems depends entirely upon an extremely low level of free ionic iron (10(-18) M) in normal tissue fluids. This in turn depends on well-oxygenated tissues where the oxidation-reduction potential (Eh) and pH control the binding of iron by unsaturated transferrin and lactoferrin. Bacterial virulence is greatly enhanced by freely available iron, such as that in fully-saturated transferrin or free haemoglobin. Following trauma a fall in tissue Eh and pH due to ischaemia, plus the reducing powers of bacteria, can make iron in transferrin freely available and abolish the bactericidal properties of tissue fluids with disastrous results for the host. Hyperbaric oxygen is a possible therapeutic measure that could restore normal bactericidal systems in infected tissues by raising the Eh and pH. 相似文献
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Jennifer E. C. Lee Louise Lemyre Pierre Mercier Louise Bouchard Daniel Krewski 《人类与生态风险评估》2005,11(6):1111-1126
This article addresses how beliefs about health risks cluster and how these relate to perceptions of risk among Canadians. A principal components analysis conducted on items reflecting various beliefs from the Canadian National Health Risk Perception Survey extracted four underlying dimensions: Cancer Dread, Trust in Regulators, Environmental Concern, and Personal Agency. Factor scores were then used to investigate relationships between belief factors and the perceived health risk of various hazards with gender, education, income, and province of residence as covariates. Environmental and Therapeutic health risk perceptions were significantly higher in respondents with high Cancer Dread and high Environmental Concern, but lower in respondents with high Trust in Regulators. Environmental health risk perceptions were lower in respondents with high Personal Agency, whereas Social health risk perceptions were higher in respondents with high Cancer Dread and Personal Agency. Results suggest that information about health risk–related beliefs can be useful in improving our understanding of the public's perceived risk of health hazards. 相似文献
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Jerome H. Barkow 《American anthropologist》2002,104(1):377-378
Defenders of the Truth: The Battle for Science in the Sociobiology Debate and Beyond. Ullica Segerstrile. New York: Oxford University Press, 2000.493 pp. 相似文献
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The self/non-self model, first proposed by F.M. Burnet, has dominated immunology for 60 years now. According to this model,
any foreign element will trigger an immune reaction in an organism, whereas endogenous elements will not, in normal circumstances, induce an immune reaction. In this paper we show that the self/non-self model
is no longer an appropriate explanation of experimental data in immunology, and that this inadequacy may be rooted in an excessively
strong metaphysical conception of biological identity. We suggest that another hypothesis, one based on the notion of continuity,
gives a better account of immune phenomena. Finally, we underscore the mapping between this metaphysical deflation from self to continuity in immunology and the philosophical debate between substantialism and empiricism about identity. 相似文献