世界知名植物分子生物学家邓兴旺

邓兴旺 ,国际植物发育遗传分子生物学界的知名学者 ,中国改革开放后在海外留学人员中做出优异成绩的杰出青年科学家 ,在拟南芥 (Ａｒａｂｉｄｏｐｓｉｓｔｈａｌｉａｎａ)光形态建成 (Ｐｈｏｔｏｍｏｒｐｈｏ ｇｅｎｅｓｉｓ)领域享有国际声誉的著名专家。 1 962年 1 0月出生在湖南沅陵 ,1 982年于北京大学生物系毕业。 1 985年获北京大学生物系植物生理学专业硕士学位 ,同年获全额奖学金赴美国加利福尼亚大学伯克利分校攻读博士学位 ,1 989年获博士学位。1 989～ 1 991年 ,进入世界著名的植物生理和分子生物学家、美国农业部植物基因表达中…     

内蒙古乌达地区下二叠统植物化石新属——拟楔羊齿属

描述了产于内蒙古乌达地区下二叠统山西组的东方拟楔羊齿Parasphenopteris orientalis Sun &; Deng (新属新种)。该植物以末二次羽片基部着生有"托叶"为特征, 区别于晚古生代其他已知植物。     

中国莽人、僜人、珞巴族与门巴族Heath-Carter法体型研究

作者于2006—2007年在云南、西藏调查了中国莽人、僜人、珞巴族、门巴族体重、身高、上臂收缩围、小腿围、肱骨内外上髁间径、股骨内外上髁间径、肱三头肌位皮褶、肩胛下位皮褶、髂前上棘位皮褶和腓肠肌位皮褶10项指标值,计算了4个族群的Heath-Carter法体型值。研究结果显示: 1)在南方族群中, 莽人身矮体轻, 身体细瘦, 皮脂菲薄, 肌肉不发达。僜人身矮体轻, 身体细瘦, 男性肌肉较发达, 皮脂厚度中等。女性肌肉发达, 皮脂厚。珞巴族与门巴族均身材高, 体重大, 身体粗壮, 皮脂厚, 肌肉发达。2)门巴族男性为偏内胚层的中胚层体型, 莽人、僜人、珞巴族男性为均衡的中胚层体型。僜人、珞巴族、门巴族女性为偏中胚层的内胚层体型, 莽人女性为偏内胚层的中胚层体型。莽人、僜人、珞巴族男性具有南亚类型族群的体型特征, 门巴族男性具有北亚类型族群体型特征。莽人女性具有南亚类型族群的体型特征, 僜人、珞巴族、门巴族女性具有北亚类型族群的体型特征。     

蚱属（Tetrix）一新种记述及罗城波蚱（Bolivaritettix luochengensis）雄性首次描记（直翅目：蚱总科）

记述采自广西东部地区蚱属(Tetrix Latreille)1新种:象州蚱(Tetrixxiangzhouensis sp.nov.),并首次报道罗城波蚱(Bolivaritettix luochengensis Deng,Zheng et Wei)的雄性个体.新种象州蚱(Tetrix xiangzhouensis sp.nov.)近似于富川蚱(Titri fuchuanensis Zheng,1998),主要区别为:(1)头顶与一眼等宽或略狭于:一眼宽;(2)头顶前缘不突出于复眼之前:(3)触角中段一节长为宽的7-8倍;(4)沟前区侧隆线略向后收缩:(5)后突到达后足胫节的2/3处;(6)前、中足股节卜缘具细毛.     

中国僜人体质特征

在西藏察隅县调查了144例(男为60例, 女为84例)僜人成人的67项体质指标, 计算了31项体质指数, 统计了指数分型情况, 对僜人的体质进行了初步分析。结果显示: (1)僜人上眼睑皱褶率、蒙古褶率极低,鼻翼高度多为中等型, 鼻根高度男多为中等型, 女多为低型, 耳垂、上唇皮肤部高度多为中等型。(2)在藏缅语族中, 僜人头面部的很多指标值小或偏小, 只有头宽值较大。僜人男女均以高头型、狭头型、中面型率最高。此外, 男性还以中头型(头长宽指数)、中鼻型率最高, 女性还以圆头型、狭鼻型率最高。(3)僜人男女均以长躯干型、中骨盆型率最高。此外, 男性以中腿型、中胸型、宽肩型率最高, 女性以亚短腿型、宽胸型、中肩型率最高。僜人男女身材均以矮型率最高, 僜人体部测量指标值均很小。(4)僜人体质特征与独龙族最为接近, 属于蒙古人种南亚类型的体质特征。     

Mussaenda lancipetala X. F. Deng & D. X. Zhang,a new species of Rubiaceae from China

Mussaenda lancipetala X. F. Deng & D. X. Zhang, a new species of Rubiaceae from Yunnan Province, Southwestern China, is described and illustrated. The new species is characterized by its reverse herkogamous sexual system, its ovate-lanceolate corolla lobes with caudate apex, and corolla tube covered with sparse farinose pubescence, by which it is clearly distinguished from other species of Mussaenda.     

中国玉叶金花属(茜草科)植物一新种

报道了在云南发现的玉叶金花属Mussaenda一新种——狭瓣玉叶金花M. lancipetala X. F. Deng ＆ D. X. Zhang。狭瓣玉叶金花的性系统为柱头缩入式雌雄异位; 花冠裂片卵状披针形且具有细长的长尖头, 花冠管外被有粉末状的毛被, 可以很容易与玉叶金花属其他种类相区别。     

Genetic polymorphism of pharmacogenomic VIP variants in the Deng people from the Himalayas in Southeast Tibet

Abstract

Little is known about polymorphic distribution of pharmacogenes among ethnicities, including the Deng people. In this study, we recruited 100 unrelated, healthy Deng people and genotyped them with respect to 76 different single-nucleotide polymorphisms by the PharmGKB database. Our results first indicated that the polymorphic distribution of pharmacogenes of the Deng people is most similar to CHD, suggesting that Deng people have a closest genetic relationship with CHD. Our data will enrich the database of pharmacogenomics and provide a theoretical basis for safer drug administration and individualized treatment plans, promoting the development of personalized medicine.     

Review: Helicobacter: Inflammation,immunology, and vaccines

Chronic inflammation induced by Helicobacter pylori infection is a critical factor in the development of peptic ulcer disease and gastric cancer. Central to this inflammation is the initiation of pro‐inflammatory signaling cascades within epithelial cells, in particular those mediated by two sensors of bacterial cell wall components, nucleotide‐binding oligomerization domain‐containing protein 1 (NOD1) and alpha‐protein kinase 1 (ALPK1). H pylori is, however, also highly adept at mitigating inflammation in the host, thereby restricting tissue damage and favoring bacterial persistence. H pylori modulates host immune responses by altering cytokine signaling in epithelial and myeloid cells, which results in increased proliferation of regulatory T cells and downregulation of effector T‐cell responses. H pylori vacuolating cytotoxin A (VacA) has been shown to play an important role in the dampening of immune responses and induction of immune tolerance capable of protecting against asthma. It is also possible to generate protective immune responses by immunization with various H pylori antigens or their epitopes, in combination with an adjuvant, though this for now has only been shown in mouse models. Novel non‐toxic adjuvants, consisting of modified bacterial enterotoxins or nanoparticles, have recently been developed that may not only enhance vaccine efficacy, but also help translate candidate vaccines to the clinic. This review will summarize the main discoveries in the past year regarding host immune responses to H pylori infection, as well as the design of new vaccine approaches against this infection.