共查询到20条相似文献，搜索用时 46 毫秒
1.
量子点在生物学中的应用 总被引：1，自引：0，他引：1
量子点是一种无机荧光材料,它具有独特的光物理特性,如其激发光谱宽且连续分布,而发射光谱呈对称分布且宽度窄,而且可通过改变量子点内核的尺寸对其发射光波长进行精细调节等。量子点的这些特性正引起人们日益广泛的关注,并在很多领域得到了应用。本文介绍了量子点的组成以及它的光学特性,同时介绍并讨论了近年来量子点在生物学领域应用的进展以及存在的问题。 相似文献
2.
量子点在生命科学中的应用 总被引：23，自引：0，他引：23
近年来 ,量子点 (半导体纳米微晶体 )的研究引起国内外研究者的广泛兴趣 ,其研究内容涉及物理、化学、材料等多学科 ,已成为一门新兴的交叉学科。虽然量子点在生物学中的应用才刚刚起步 ,但是已经取得了有意义的进展 ,成为人们极为注意的一个热点。现就量子点的光学特性、制备方法以及在生物学中的研究进展和应用前景作一简要综述 相似文献
3.
量子点是近几年发展起来的新型纳米材料,虽然研究起步较晚,但因其独特的电学和光学性质而成为人们关注的热点,在生物医学等多个领域有突破性的研究进展。本文主要介绍量子点的性质、制备方法及其在生物医学中的应用进展和存在的问题。 相似文献
4.
5.
量子点荧光探针是近几年发展起来的一种新型荧光标记物,拥有荧光染料及荧光蛋白所不能比拟的独特优势,已经在细胞功能研究及细胞表面和内部功能分子的探测、组织的成像和病灶的定位等方面得到了较为广泛的应用。本文对量子点的光学特性、生物化修饰及其在生物成像等方面的应用进展进行了较为详细的介绍,并展望了其应用发展。 相似文献
6.
半导体量子点具有长时间、多目标和灵敏度高等独特的光化学性质,这些特性使量子点成为细胞标记和生物应用中得到了广泛的应用。利用量子点目标定位癌细胞,对于寻找癌变部位具有指导的作用。近年来,利用量子点作为光动力学治疗癌症的能量供体也得到了一定的研究。简单地介绍了量子点独特的光学性质,并从量子点标记癌细胞、可视化癌细胞表面功能和在光动力学治疗癌症等方面综述了量子点在癌症诊断和治疗中的应用。 相似文献
7.
量子点的生命科学中的应用 总被引：5，自引：0，他引：5
近年来,最子点（半导体纳米微晶体）的研究引起国内外研究者的广泛兴趣,其研究内容涉及物理、化学、材料等多材料,已成为一门新兴的交叉学科。虽然量子点在生物学中的应用才刚刚起步,但是已经取得了意义的进展,成为人们极为注意的一个热点。现就量子点的光学特性、制备方法以及在生物学中的研究进展和应用前景作一简要综述。 相似文献
8.
半导体量子点作为新型荧光标记物,在生物医学领域具有重要应用．与传统的有机染料及荧光蛋白等荧光标记物相比,半导体量子点具有发光颜色可调、激发范围宽、发射光谱窄、化学及光稳定性好、表面化学丰富以及生物偶联技术成熟等诸多优势,为生命体系的靶向示踪,高灵敏、原位、实时、动态荧光成像,DNA及蛋白质检测,靶向药物,临床医学,生物芯片和传感器等研究提供了新的发展契机．基于作者在半导体量子点生物荧光成像和安全性评价研究的基础,综述了半导体量子点荧光标记物在生命科学与医学领域应用的研究热点,并对半导体量子点荧光标记技术走向实用面临的挑战进行了评述． 相似文献
9.
纳米技术的兴起,对生物医学领域的变革产生了深远的影响。纳米材料是纳米技术发展的重要基础,它具有许多传统材料所不具备的独特的理化性质,因此在生物医学、传感器等重要技术领域有着广泛的应用前景。对几类常见的纳米材料包括纳米金、量子点、磁性纳米粒子、碳纳米管和硅纳米线在蛋白质、DNA、金属离子以及生物相关分子检测方面的应用进行综述。 相似文献
10.
11.
12.
Nanoparticles of cadmium selenide (CdSe) doped with europium, were synthesized as stabilizing agents using thioglycolic acid ligand. This method is based on the enhancing effect of CdSe quantum dots (QDs) doped with europium on chemiluminescence (CL) emission. This emission was generated by mixing CdSe QDs with manganese (II), iron (II) and chrome (II) sulfates as catalysts in the presence of hydrogen peroxide (H2O2). The structural characteristics and morphology of these nanoparticles were investigated by scanning electron microscopy, Fourier transform infrared spectroscopy, ultraviolet–visible absorption spectroscopy, X‐ray pattern and dynamic light scattering methods. The CdSe QDs doped with europium were used as the sensitizer in a luminol?hydrogen peroxide CL system. The sensitized CdSe QDs were analyzed for antibacterial activity against Gram‐positive or Gram‐negative bacteria. The results showed that the CdSe QDs are effective against all the studied bacteria, effectiveness was especially higher for Bacillus subtilis. 相似文献
13.
Thomas P. Brennan Pendar Ardalan Han‐Bo‐Ram Lee Jonathan R. Bakke I‐Kang Ding Michael D. McGehee Stacey F. Bent 《Liver Transplantation》2011,1(6):1169-1175
Functioning quantum dot (QD) sensitized solar cells have been fabricated using the vacuum deposition technique atomic layer deposition (ALD). Utilizing the incubation period of CdS growth by ALD on TiO2, we are able to grow QDs of adjustable size which act as sensitizers for solid‐state QD‐sensitized solar cells (ssQDSSC). The size of QDs, studied with transmission electron microscopy (TEM), varied with the number of ALD cycles from 1‐10 nm. Photovoltaic devices with the QDs were fabricated and characterized using a ssQDSSC device architecture with 2,2',7,7'‐tetrakis‐(N,N‐di‐p methoxyphenylamine) 9,9'‐spirobifluorene (spiro‐OMeTAD) as the solid‐state hole conductor. The ALD approach described here can be applied to fabrication of quantum‐confined structures for a variety of applications, including solar electricity and solar fuels. Because ALD provides the ability to deposit many materials in very high aspect ratio substrates, this work introduces a strategy by which material and optical properties of QD sensitizers may be adjusted not only by the size of the particles but also in the future by the composition. 相似文献
14.
15.
16.
Mahendra R. Mahajan;Pravin O. Patil; 《Luminescence》2024,39(7):e4835
In this study, we developed a new fluorescence “on–off–on” sensor utilizing water-soluble cobalt/zinc–nitrogen co-doped graphene quantum dots (Co/Zn-N-GQDs) to recognize quinalphos pesticide in vegetable and fruit samples. Primarily, the synthesis method employed a one-pot hydrothermal approach, using betel leaves as a natural precursor and cobalt (“Co”), zinc (“Zn”), and urea (“N”) as dopant sources. The Co/Zn-N-GQDs probes underwent comprehensive analytical characterization. The Co/Zn-N-GQDs were synthesized with a remarkable luminescence yield of 31.49%, exhibiting excitation at 320 nm and emission peak at 393 nm. Interestingly, the luminescence of Co/Zn-N-GQDs was selectively “Turned Off” by Cu2+ via a static quenching setup. Remarkably, quenched fluorescence was surprisingly reactivated upon adding quinalphos to the quench setup, indicating a direct correlation between luminescence reactivation and quinalphos concentration. Briefly, this phenomenon is ascribed to the functional groups in quinalphos, such as quinoxalinyl and phosphorothioate, which chelate with Cu2+ ions, disrupting the nonfluorescent Cu2+-Co/Zn-N-GQDs complex. The design sensor demonstrated a limit of detection (LOD) of 0.11 μM and a broad linear span of 0.5 to 200 μM. In conclusion, Cu2+-Co/Zn-N-GQDs sensor showed immediate applicability, stability, and reproducibility, making it highly effective for quinalphos sensing in various samples. 相似文献
17.
Hoshino A Fujioka K Oku T Nakamura S Suga M Yamaguchi Y Suzuki K Yasuhara M Yamamoto K 《Microbiology and immunology》2004,48(12):985-994
Fluorescent nanocrystal quantum dots (QDs) have the potential to be applied to bioimaging since QDs emit higher and far longer fluorescence than conventional organic probes. Here we show that QDs conjugated with signal peptide obey the order to transport the assigned organelle in living cells. We designed the supermolecule of luminescent QDs conjugated with nuclear- and mitochondria-targeting ligands. When QDs with nuclear-localizing signal peptides were added to the culture media, we can visualize the movements of the QDs being delivered into the nuclear compartment of the cells with 15 min incubation. In addition, mitochondrial signal peptide can also transport QDs to the mitochondria in living cells. In conclusion, these techniques have the possibility that QDs can reveal the transduction of proteins and peptides into specific subcellular compartments as a powerful tool for studying intracellular analysis in vitro and even in vivo. 相似文献
18.
Water-soluble quantum dots for biomedical applications 总被引：6，自引：0，他引：6
Yu WW Chang E Drezek R Colvin VL 《Biochemical and biophysical research communications》2006,348(3):781-786
Semiconductor nanocrystals are 1-10nm inorganic particles with unique size-dependent optical and electrical properties due to quantum confinement (so they are also called quantum dots). Quantum dots are new types of fluorescent materials for biological labeling with high quantum efficiency, long-term photostability, narrow emission, and continuous absorption spectra. Here, we discuss the recent development in making water-soluble quantum dots and related cytotoxicity for biomedical applications. 相似文献
19.
Kasra Sardashti Richard Haight Tayfun Gokmen Wei Wang Liang‐Yi Chang David B. Mitzi Andrew C. Kummel 《Liver Transplantation》2015,5(10)
The effort to develop earth‐abundant kesterite solar cells has led to an approximate doubling of the power conversion efficiency over the past five years to 12.6%, primarily due to increases in short‐circuit current and fill factor; open‐circuit voltage has resisted similar change, limiting further efficiency improvement. In the present investigation, Auger nanoprobe spectroscopy, X‐ray/ultraviolet photoelectron spectroscopy, and device characterization are used to provide a comprehensive understanding of the role of grain boundaries and interfaces in limiting performance in kesterite‐based devices. High photovoltaic performance is found to correlate with grain boundaries that are Cu‐depleted and enriched with SnOx. The formation of this bulk‐like oxide at grain boundaries with type I band offset provides a unique effective passivation that limits electron‐hole recombination. Building on these new insights, photovoltaic device simulations are performed that show optimized electrostatic designs can compensate for bulk defects, allowing efficiencies closer to the theoretical limit. 相似文献
20.
Infectious diseases caused by pathogens have become a life-threatening problem for millions of people around the world in recent years. Therefore, the need of efficient, fast, low-cost and user-friendly biosensing systems to monitor pathogen has increased enormously in the last few years. This paper presents an overview of different fluorescent labels and the utilization of fluorescence-based biosensor techniques for rapid, direct, sensitive and real-time identification of bacteria. In these biosensors, organic dyes, nanomaterials and rare-earth elements are playing an increasing role in the design of biosensing systems with an interest for applications in bacterial analysis. 相似文献