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1.
Setsuko Tohno Yoshiyuki Tohno Motoharu Hayashi Yumi Moriwake Takeshi Minami Fumio Nishiwaki Tsutomu Araki 《Biological trace element research》2001,82(1-3):77-86
To examine whether the calcium accumulation in the arteries is related to the way of walk or not, the calcium contents were
determined in various arteries of Japanese monkeys of quadrupedal walk by inductively coupled plasma-atomic emission spectrometry.
Japanese monkeys consisted of five males and four females, ranging in age from 2 to 29 yr.
Age-related changes of the calcium content were examined in various monkey arteries. Significant relationships between age
and calcium content were found in the arteries, such as the axillary, brachial, radial, subclavian, common carotid, common
iliac, and femoral arteries, but not statistically in the thoracic and abdominal aortas, ulnar, external iliac, internal iliac,
popliteal, and tibial arteries.
The average contents of calcium were compared between the two groups of the monkeys below 14 yr and over 24 yr of age. Below
14 yr, the calcium content was a little higher in the arteries, such as the common, external and internal iliac, and femoral
arteries than that of the other ones. Over 24 yr, the calcium content increased remarkably in the arteries, such as the thoracic
aorta, common, internal and external iliac, common carotid, and subclavian arteries. The calcium contents of the thoracic
aorta, common, internal and external iliac, common carotid, and subclavian arteries increased by more than two times over
24 yr compared with those below 14 yr.
In a comparison between the calcium contents of the arteries in the anatomically corresponding regions of the upper and lower
limbs, no statistically significant differences were found in the subjects over 24 yr as well as the subjects 2–29 yr of age.
The calcium accumulation in the arteries of monkeys with aging was different from those in the arteries of humans, because
in the case of human, a very high accumulation of calcium occurred in the arteries of the lower limb with aging in comparison
with those in the upper limbs.
Therefore, it is likely that different ways of walk or different species are partly affected in the calcium accumulation in
the arteries with aging. 相似文献
2.
Tohno S Tohno Y Hayashi M Minami T Moriwake Y Azuma C Ohnishi Y 《Biological trace element research》2003,95(2):173-184
To examine whether the calcium accumulation in aged arteries is related to the way of walking, the mineral contents were determined
in the arteries of Japanese monkeys of quadrupedal walk by inductively coupled plasma-atomic emission spectrometry. Sixteen
Japanese monkeys consisting of 7 males and 9 females ranging in age from 2 to 33 yr were studied.
The accumulation of calcium, phosphorus, and magnesium occurred progressively in most, but not all, of the arteries with aging.
It was found that independent of the upper and lower limbs, a higher accumulation of calcium, phosphorus, and magnesium occurred
in the arteries of the proximal regions with aging, compared with the arteries of the distal regions.
In a comparison between the arteries of anatomically corresponding regions of the upper and lower limbs, the accumulation
of calcium and magnesium was 20–60% higher in the external iliac and femoral arteries of the lower limb than in the axillary
and brachial arteries of the upper limb. Regarding phosphorus, the accumulation was 20–120% higher in the external iliac and
femoral arteries than in the axillary and brachial arteries. It was known that in humans, the accumulation of calcium, phosphorus,
and magnesium was three to seven times higher in the arteries of the lower limb than in the arteries of the upper limb. It
is clear that there is a very significant difference in the accumulation of calcium and magnesium in the arteries of the lower
limbs between Japanese monkeys and humans. The present study suggests that the accumulation of calcium and magnesium in the
arteries of the lower limb with aging is affected by the way of walking. 相似文献
3.
Gonzalez-Reimers E Rodriguez-Moreno F Martinez-Riera A Mas-Pascual A Delgado-Ureta E Galindo-Martin L Arnay-de la Rosa M Santolaria-Fernandez F 《Biological trace element research》1999,68(1):41-49
To elucidate accumulation of minerals in human iliac arteries with aging, the content of minerals was analyzed by inductively
coupled plasma atomic emission spectrometry. Bilateral common, internal, and external iliac arteries of 16 men and 8 women,
ranging ages from 65 to 93 yr, were examined. It was found that an extremely high accumulation of calcium and phosphorus occurred
in the common iliac artery at old age, being higher than that of the internal and external iliac arteries. It should be noted
that the accumulation of calcium and phosphorus is the highest in the common iliac artery among the human arteries examined
to date.
Regarding sexual differences, the content of calcium and phosphorus in the common and internal iliac arteries was higher in
women than in men, whereas their content in the external iliac artery was lower in women than in men. 相似文献
4.
Yoshiyuki Tohno Setsuko Tohno Yumi Moriwake Cho Azuma Yoshiaki Ohnishi Takeshi Minami 《Biological trace element research》2001,82(1-3):9-19
To elucidate the accumulation of elements in the arteries with aging, the authors investigated age-related changes of elements
in human arteries, such as the thoracic aorta, femoral, basilar, coronary, radial, and common iliac arteries by inductively
coupled plasma-atomic emission spectrometry. The subjects consisted of 17 men and 9 women, ranging in age from 55 to 92 yr
in the cases of the five arteries, except for the common iliac arteries, in which the subjects consisted of 16 men and 8 women,
ranging in age from 65 to 93 yr.
It was found that there were significantly direct correlations between calcium and phosphorus contents and between calcium
and magnesium contents in all of the six arteries: thoracic aorta, femoral, basilar, coronary, radial, and common iliac arteries.
Significantly direct correlations were also found between phosphorus and magnesium contents in the five arteries, except for
the basilar artery. In contrast, significantly inverse correlations were found between calcium and sulfur contents and between
phosphorus and sulfur contents in the four arteries, except for the coronary and radial arteries. These revealed that the
accumulation of calcium and phosphorus in the arteries was accompanied by an increase of magnesium in the arteries and by
a decrease of sulfur in the arteries. 相似文献
5.
Setsuko Tohno Yoshiyuki Tohno Takeshi Minami Yumi Moriwake Masako Utsumi Fumio Nishiwaki Masa-Oki Yamada Yuko Okazaki 《Biological trace element research》1998,63(3):177-183
To elucidate accumulation of minerals in the human arteries, the relative contents (RCs) of minerals in the arteries of the
upper and lower limbs were analyzed by inductively coupled plasma atomic emission spectrometry.
It was found that the RCs of calcium and phosphorus in the femoral and popliteal arteries of the lower limb increased with
aging, whereas those in the axillary and radial arteries of the upper limb did not increase with aging. This result indicates
that higher accumulation of calcium and phosphorus occurs in the arteries of the lower limb with aging as compared with that
in the arteries of the upper limb, and the prevalence of arteriosclerosis increases in the arteries of the lower limb with
aging but not in the arteries of the upper limb. 相似文献
6.
Azuma C Tohno S Mahakkanukrauh P Tohno Y Satoh H Chomsung R Minami T Moriwake Y Utsumi M Vaidhayakarn P 《Biological trace element research》2003,95(3):211-218
To analyze the accumulation of elements in the rami of the coronary arteries, the authors determined element contents in both
the coronary arteries and their rami of the Thai by inductively coupled plasma-atomic emission spectrometry. The subjects
consisted of 13 men and 6 women, ranging in age from 34 to 83 yr. It was found that a higher accumulation of calcium and phosphorus
occurred in the proximal sites of coronary arteries such as the anterior descending, right coronary, left coronary, and circumflex
arteries than the distal sites such as the diagonal, lateral, conus, acute marginal, and posterior descending arteries. The
accumulation of calcium and phosphorus in the anterior descending and right coronary arteries of the Thai increased remarkably
in the fifties, thereafter decreased, and increased again in the eighties. It should be noted that a very high accumulation
of calcium and phosphorus in the coronary arteries occurred in the fifties. In regard to relationships among the average contents
of elements in the coronary arteries and their rami, it was found that there were very significant direct correlations between
calcium and phosphorus contents, between calcium and magnesium contents, and between phosphorus and magnesium contents. These
results suggested that as calcium and phosphorus increased in the coronary arteries and their rami, magnesium increased simultaneously
in all of the coronary arteries and their rami. 相似文献
7.
Ongkana N Tohno S Payo IM Azuma C Moriwake Y Minami T Tohno Y 《Biological trace element research》2007,117(1-3):23-38
To elucidate whether the accumulation of elements occurred simultaneously in the various arteries with aging, the authors
investigated age-related changes of elements in the eight arteries, such as the thoracic and abdominal aortas and the coronary,
common carotid, pulmonary, splenic, common iliac, and uterine arteries, and the relationships in the element contents among
their arteries. After ordinary dissection by medical students was finished, the thoracic and abdominal aortas and the coronary,
common carotid, pulmonary, splenic, common iliac, and uterine arteries were resected from the subjects, who ranged in age
from 58 to 94 yr. The element contents were analyzed by inductively coupled plasma-atomic emission spectrometry. It was found
that the accumulation of Ca was the highest in the common iliac artery and decreased in the order of the uterine artery, abdominal
aorta, coronary artery, thoracic aorta, splenic artery, common carotid artery, and pulmonary artery. Regarding the relationships
in the element contents among the eight arteries, it was found that there were significant direct correlations in the contents
of Ca, P, Mg, Zn, Fe, and Na between the coronary and splenic arteries, and there were significant correlations in the contents
of Ca, P, and Mg between the abdominal aorta and pulmonary artery. 相似文献
8.
Tohno S Tohno Y Moriwake Y Azuma C Ohnishi Y Minami T 《Biological trace element research》2001,84(1-3):57-66
To elucidate the mechanism of element accumulations in the arteries with aging, the authors investigated the mass ratios among
calcium, phosphorus, and magnesium in the common iliac arteries by inductively coupled plasma-atomic emission spectrometry.
The subjects consisted of 16 men and 8 women, ranging in age from 65 to 93 yr.
It was found that there were extremely significant correlations between calcium and phosphorus contents, between calcium and
magnesium contents, and between phosphorus and magnesium contents in the common iliac arteries. In regard to the mass ratio,
although the mass ratio of calcium to phosphorus was almost constant, the mass ratios of magnesium to calcium and phosphorus
were different at early and advanced stages of the accumulation of calcium and phosphorus. It was found that both the mass
ratios of magnesium to calcium and phosphorus were higher at an early stage of the accumulation of calcium and phosphorus
in the arteries than at an advanced stage of the accumulation. 相似文献
9.
Tohno Y Tohno S Mahakkanukrauh P Vaidhayakarn P Somsarp V Minami T Moriwake Y Azuma C 《Biological trace element research》2001,84(1-3):19-35
To elucidate compositional changes of arteries with aging, the authors previously investigated age-related changes of mineral
contents in the various arteries of Japanese and Japanese monkey. To examine whether there were differences between races
in regard to age-related changes of mineral contents and the relationships among element contents in the arteries, the authors
investigated the arteries of Thai. The subjects consisted of 13 men and 3 women, ranging in age from 39 to 84 yr. After the
ordinary dissection at Chiang Mai University was finished, abdominal aortas, common iliac, internal iliac, and external iliac
arteries were resected and the element contents were determined by inductively coupled plasma-atomic emission spectrometry.
The contents of calcium, phosphorus, and magnesium became the highest in the fifties in the abdominal aorta, common iliac,
and external iliac arteries, whereas the contents of calcium and magnesium became the highest in the sixties in the internal
iliac artery, and decreased thereafter. In regard to relationships among element contents, it was found that there were high
correlations between calcium and phosphorus contents, between calcium and magnesium contents, and between phosphorus and magnesium
in all of the abdominal aortas and three iliac arteries. The mass ratios of magnesium to calcium and phosphorus were each
similar in the abdominal aorta, common iliac, and internal iliac arteries, except for the external iliac artery, in which
it was slightly high. These revealed that as calcium and phosphorus increased in the arteries with aging, magnesium increased
in the arteries as well. The differences between the arteries of Thai and Japanese were discussed in the present article. 相似文献
10.
Tohno S Tohno Y Hayashi M Mahakkanukrauh P Chomsung R Azuma C Moriwake Y Minami T Araki T 《Biological trace element research》2005,106(3):211-217
To examine whether an accumulation of elements in the arteries was affected by the way of walking, the authors investigated
age-related changes of elements in the arteries of the Japanese, Thai, and Japanese monkeys. After the ordinary dissections
by medical students were finished, the subclavian, axillary, brachial, radial, common iliac, externaliliac, femoral, and posterior
tibial arteries were resected from the subjects of the Japanese and Thai over 60 yr of age and they were also resected from
the Japanese monkeys over 20 yr of age. The element content was determined by inductively coupled plasma-atomic emission spectrometry.
It was found that in an comparison between the arteries of anatomically corresponding regions, the average content of Ca was
eight times or four times higher in the arteries of the lower limb than in the arteries of the upper limb in the Japanese
or Thai, over 60 yr of age, respectively. In the Japanese monkeys over 20 yr of age, the average content of Ca was 1.2 times
higher in the arteries of the lower limb than in the arteries of the upper limb. The result suggests that an accumulation
of Ca in the arteries of the lower limb with aging is affected by the way of walking. 相似文献
11.
Naganuma T Tohno Y Yamasaki M Tohno S Azuma C Minami T Morikawa H 《Biological trace element research》2004,101(3):203-210
To elucidate compositional changes of the rami of the internal iliac artery with aging, the authors investigated age-related
changes of the calcium content in the uterine, internal pudendal, umbilical, and obturator arteries by inductively coupled
plasma-atomic emission spectrometry. After an ordinary dissection was finished, the uterine, internal pudendal, umbilical,
and obturator arteries were resected from 10 female subjects, and the internal pudendal, umbilical, and obturator arteries
were resected from 10 male subjects. The female subjects ranged in age from 52 to 96 yr, and the male subjects ranged in age
from 63 to 88 yr. The calcium content in the uterine artery began to increase in the seventies and increased markedly in the
nineties. In the internal pudendal artery, the calcium content hardly increased up to the eighties and increased significantly
in the nineties. In contrast, the calcium content did not change in both the umbilical and obturator arteries with advancing
age. It was found that the average content of calcium was the highest in the uterine artery and decreased in the order internal
pudendal, umbilical, and obturator arteries. The average content of calcium in the uterine arteries corresponded to 46-fold
the amount of the women's obturartor arteries, in which it was the lowest. In the cases of men, the average content of calcium
was higher in the order of the internal pudendal, umbilical, and obturator arteries. Regarding the average content of calcium,
the order internal pudendal, umbilical, and obturator arteries of the men was consistent with that of the women. 相似文献
12.
Ohnishi Y Tohno S Mahakkanukrauh P Tohno Y Vaidhayakarn P Azuma C Satoh H Moriwake Y Chomsung R Minami T 《Biological trace element research》2003,96(1-3):71-92
To elucidate whether the extent of element accumulation in the arteries and cardiac valves with aging was different between
different races, the authors investigated the accumulation of elements in the arteries and cardiac valves of the Thai with
aging and the relationships among elements in the cardiac valves. After ordinary dissection at Chiang Mai University was finished,
16 arteries and 4 cardiac valves were resected and element contents were determined by inductively coupled plasma-atomic emission
spectrometry.
In the 16 arteries, the average content of calcium was the highest in the site of the abdominal aorta ramifying into the common
iliac arteries, and it decreased in the order internal iliac, coronary, abdominal aorta, common iliac, external iliac, superior
mesenteric, inferior mesenteric, thoracic aorta, brachial, radial, common carotid, subclavian, ulnar, axillary, renal, and
internal thoracic arteries. The average contents of phosphorus and magnesium in respective arteries were parallel with the
average contents of calcium, except for the coronary artery. In comparison with the arteries of the Japanese, the trend of
calcium accumulation in the arteries of the Thai was almost similar to that in the arteries of the Japanese, except for the
coronary artery and thoracic aorta. The calcium accumulation in the coronary artery was much higher in the Thai than in the
Japanese, whereas that in the thoracic aorta was lower in the Thai than in the Japanese.
Regarding elements in the cardiac valves, the calcium content increased remarkably in the seventies in the aortic valve and
in the nineties in the pulmonary valve, but it hardly increased in both the mitral and tricuspid valves with aging. The average
content of calcium was the highest in the aortic valve, and it decreased in the order pulmonary, tricuspid, and mitral valves.
Regarding the relationship among elements in the aortic valves, it was found that there were extremely significant direct
correlations among the contents of calcium, phosphorus, and magnesium, whereas there were significant direct correlations
between zinc and either calcium or phosphorus contents. Although significant correlations were found between sulfur and the
other element contents in the aortic valves of the Japanese, no significant correlations were found between them in the aortic
valves of the Thai. In the mitral valves, extremely or very significant direct correlations were found among the contents
of calcium, phosphorus, magnesium, and sulfur, with some exceptions that there were no significant correlations between phosphorus
and either magnesium or sulfur contents.
In addition, no significant correlation was found in the calcium content between the aortic valve and coronary artery in the
same individuals. 相似文献
13.
Ongkana N Zhao XZ Tohno S Azuma C Moriwake Y Minami T Tohno Y 《Biological trace element research》2007,119(2):120-127
To elucidate compositional changes of the pineal body with aging, the authors investigated age-related changes of elements
in the pineal body. After the ordinary dissection by medical students was finished, the pineal bodies and seven arteries were
resected from the subjects ranging in age from 58 to 94 years. The element contents were determined by inductively coupled
plasma atomic emission spectrometry. It was found that a high accumulation of Ca and P occurred in the pineal bodies with
aging. Regarding the relationships among the elements, it was found that there were significant direct correlations among
the contents of Ca, P, and Mg. With regard to the relationships between the pineal body and the arteries, no significant correlations
were found in the Ca content between the pineal body and the arteries, such as the thoracic and abdominal aortas and the coronary,
common carotid, pulmonary, splenic, and common iliac arteries. 相似文献
14.
To examine whether an accumulation of elements in the arteries with aging differs between human and animal, the authors investigated
the relationships among element contents in the arteries of the Japanese monkeys. The Japanese monkeys consisted of five males
and four females, ranging in age from 2 to 29 yr. The aorta, common and external iliac, femoral, common carotid, subclavian,
and axillary arteries were resected from the monkeys and element contents were determined by inductively coupled plasma-atomic
emission spectrometry. It was found that there were very high correlations between calcium and phosphorus contents, between
calcium and magnesium contents, and between phosphorus and magnesium contents in all of the monkey arteries. In addition,
significant correlations were found among the other element contents in some, but not all of the arteries. These results were
consistent with the foregoing findings of the human arteries. It is likely that magnesium forms compounds with phosphorus
or calcium in the monkey arteries. 相似文献
15.
Tohno S Mahakkanukrauh P Tohno Y Vaidhayakarn P Minami T Somsarp V Moriwake Y Chomsung R Azuma C 《Biological trace element research》2002,87(1-3):69-82
To examine whether there were differences between races in regard to age-related changes of mineral contents and the relationships
among element contents in the arteries, the authors investigated the coronary arteries of Thai and Japanese. The Thai subjects
consisted of 13 men and 3 women, ranging in age from 39 to 84 yr, whereas the Japanese subjects consisted of 17 men and 9
women, ranging in age from 55 to 92 yr. After the ordinary dissections at Chiang Mai University and Nara Medical University
were finished, the coronary arteries were resected and the element contents were determined by inductively coupled plasma-atomic
emission spectrometry. In the Thai, an accumulation of calcium and phosphorus began to occur in the forties and increased
markedly in the fifties, whereas in the Japanese, an accumulation of calcium and phosphorus began to occur in the seventies
and increased markedly in the nineties. The result revealed that an accumulation of calcium and phosphorus occurred earlier
in the Thai than in the Japanese. Regarding the relationships among element contents, extremely significant correlations were
found between calcium and phosphorus contents, between calcium and magnesium contents, and between phosphorus and magnesium
contents in both the coronary arteries of the Thai and the Japanese. As far as the coronary arteries with a very high accumulation
of calcium and phosphorus, the mass ratios of magnesium to calcium and phosphorus were lower in the coronary arteries of the
Thai in comparison with the Japanese. 相似文献
16.
Mahakkanukrauh P Tohno S Tohno Y Chomsung R Azuma C Moriwake Y Minami T 《Biological trace element research》2004,100(3):205-214
To examine whether there were differences between races in regard to the relationships among element contents in the arteries,
the authors investigated the relationships among the average contents of calcium, phosphorus, sulfur, and magnesium in the
18 kinds of the Thai artery. After ordinary dissection by medical students at Chiang Mai University was finished, the thoracic
and abdominal aortas, ramifying site of the abdominal aorta into the common iliac arteries, coronary, common carotid, internal
thoracic, subclavian, axillary, brachial, radial, superior and inferior mesenteric, renal, common iliac, internal iliac, and
external iliac arteries were resected from the subjects who consisted of 12 men and 3 women, ranging in age from 39 to 84
yr. The femoral and posterior tibial arteries were resected from the subjects, consisting of 15 men and 5 women, ranging in
age from 25 to 88 yr. The element content of the arteries was analyzed by inductively coupled plasma-atomic emission spectrometry.
It was found that there were extremely significant direct correlations among the average contents of calcium, phosphorus,
and magnesium in the 18 kinds of the Thai artery, but no significant correlations were found between the average contents
of sulfur and elements, such as calcium, phosphorus, and magnesium. These results were in agreement with those of the Japanese
arteries. Therefore, it was suggested that there was no significant difference between the arteries of the Thai and the Japanese
in the relationships among calcium, phosphorus, sulfur, and magnesium. 相似文献
17.
Yoshiyuki Tohno Setsuko Tohno Takeshi Minami Masayo Ichii Yoko Okazaki Masako Utsumi Fumio Nishiwaki Yumi Moriwake Masa-oki Yamada Tsutomu Araki 《Biological trace element research》1996,54(1):23-31
The relative contents (RCs) of mineral elements in aortae and cerebral arteries from 23 subjects, with ages ranging between
45 and 99 yr, were analyzed by inductively coupled plasma atomic emission spectrometry. The RCs of calcium, phosphorus, and
magnesium in the aortae increased markedly after the age of 70. While the RC of sulfur in aortae decreased gradually after
that age. It was found that accumulation of calcium and phosphorus occurred primarily in the tunica media of aorta, and secondarily
in the tunica intima. Furthermore, the RCs of calcium, phosphorus, and magnesium in cerebral arteries increased markedly after
the age of 70, whereas the RC of sulfur in cerebral arteries decreased after age 70. It was found that accumulation of calcium
and phosphorus in the cerebral arteries were 30 and 60%, respectively, lower than those in the aortae with ages ranging between
45 and 99 yr. 相似文献
18.
Mahakkanukrauh P Tohno S Tohno Y Azuma C Ongkana N Moriwake Y Minami T 《Biological trace element research》2005,106(3):219-229
To examine whether there were differences between reces in regard to age-related changes of elements and the relationships
among elements in the arteries, the authors investigated both the renal arteries of Thai and Japanese. The Thai subjects consisted
of 27 men and 11 women, ranging in age from 27 to 88 yr, whereas the Japanese subjects consisted of 19 men and 26 women, ranging
in age from 61 to 99 yr. After the ordinary dissections at Chiang Mai University and Nara Medical University were completed,
the bilateral renal arteries were resected and the element contents were determined by inductively coupled plasma-atomic emission
spectrometry. In the Thai, a slight accumulation of calcium and phosphorus occurred in the fifties, but thereafter headly
increased. In contrast, in the Japanese, an accumulation of calcium and phosphorus began to occur in the seventies and increased
markedly in the eighties. The result reveraled that a higher accumulation of calcium and phosphorus occurred in the renal
arteries of the Japanese in old age compared with those of the Thai. Regarding the relationships among elements, extremely
or very significant direct correlations were found among the contents of calcium, phosphorus, magnesium, and sodium in both
the renal arteries of the Thai and Japanese, except for magnesium and sodium contents in the renal arteries of the Thai. 相似文献
19.
Setsuko Tohno Yoshiyuki Tohno Takeshi Minami Yuko Okazaki Masako Utsumi Fumio Nishiwaki Yumi Moriwake Takashi Naganuma Masa-oki Yamada Tsutomu Araki 《Biological trace element research》1997,57(1):27-37
The relative contents (RCs) of elements in the femoral arteries as well as the thoracic aorta, coronary, basilar, and radial
arteries from 26 subjects within the age range between 55 and 92 yr old, were analyzed by inductively coupled plasma atomic
emission spectrometry.
The RCs of calcium and phosphorus in the femoral arteries started to increase before the age of 60 yr. The RCs of magnesium
increased after the age of 70 yr. However, the RCs of sulfur did not change significantly within the age range between 55
and 92 yr.
With regard to localization of the mineral accumulations in the femoral arterial wall, it was found that the accumulations
of calcium and phosphorus occurred only in the tunica media, only in the tunica intima, or in both the tunica media and the
tunica intima. The manner of accumulation of calcium and phosphorus in the femoral arterial wall was different from that in
the aortic wall.
The average RCs of calcium in the 26 specimens were the highest in the femoral artery, followed in descending order by the
thoracic aorta, coronary, basilar, and radial arteries. The average RCs of phosphorus were highest in the thoracic aorta,
followed by the coronary, femoral, basilar, and radial arteries. It is noted that the accumulation of mineral elements never
occurred uniformly in all the arteries. 相似文献
20.
Fukushima S Araki T Tohno Y 《Journal of PHYSIOLOGICAL ANTHROPOLOGY and Applied Human Science》2005,24(4):493-496
Vascular calcification is commonly associated with aging. Quantification of calcium accumulation in vessel walls is important in understanding the mechanisms of vascular calcification. To elucidate age-related change of calcification, site dependence of calcification, and the effect of hemodynamic stress on calcification, we measured calcium contents in various blood vessels with atomic emission spectrometry and simulated blood flow in the vessels by computational fluid dynamics. The content of calcium in the arteries increased progressively with aging while there is no change in the veins. The higher accumulation of calcium occurred in the arteries of the lower limb in comparison to the arteries of the upper limb. In the arterial bifurcation, there was the correlation at hemodynamic stress distribution and calcium content. The results of this study quantitatively support clinical findings of nonuniform calcification, and suggest that hemodynamic stress affects vascular calcification. 相似文献