Resonance excitation of the magnetosphere by hydromagnetic waves incident from solar wind

The eigenfrequencies and eigenmodes of an MHD cavity in the front part of the magnetosphere and its excitation by monochromatic hydromagnetic waves incident onto the magnetosphere from solar wind are studied theoretically in the model of a plane-stratified plasma. The eigenmodes are damped due to both their absorption at the Alfvén resonance points and their emission into solar wind through the magnetopause, which is partially transparent for the excited waves. It is shown that, due to the influence of the magnetospheric cavity, the pumping of the magnetosphere by the incident waves is resonance in character. The waves penetrate into the magnetosphere only if their frequencies lie in narrow spectral ranges near the eigenfrequencies of the cavity, the width of these ranges being on the order of the damping rate of the eigenmodes. Waves with other frequencies are almost completely reflected from the magnetopause.     

Tuning,coupling and matching of a resonant cavity in microwave exposure system for biological objects

A new microwave exposure system for biological experiments with well-defined exposure conditions and improved control of the exposure parameters consisting of variable frequency power source, coaxial to waveguide transition, matching network and single-mode resonant cavity with movable shorting plunger was fabricated and characterized. The introduction of a biological sample into a resonant cavity has a large impact on its field configuration and port impedance. As such, the properties, geometry and position of the biological sample become a part of the electrical properties of the microwave circuit. With that change, the electrical properties of the resonant cavity, such as impedance, quality factor and resonant frequency, also change. In this study, an appropriate coupling system with effective power transfer and an algorithm to tuning and coupling of resonant cavity in resonance before and after the introduction of biological sample have been proposed. This procedure will lead to a known dose distribution within the biological sample and allow a better comparison with other studies. Coupling of the electromagnetic energy into a resonant cavity was experimentally investigated. Graphical representation of cavity impedance in case of undercoupled, critically coupled and overcoupled cavity has been presented. Critical coupling of an empty resonant cavity has been accomplished at voltage standing wave ratio (VSWR) 1.01, at resonance frequencies 900 and 947.5 MHz. Critical coupling with the introduction of a biological sample has been accomplished at VSWR ≤ 1.07 for frequency bandwidth 1 MHz and VSWR ≤ 1.5 for frequency bandwidth up to 5 MHz with central frequency 947.5 MHz.     

Resonant excitation of the magnetosphere by stochastic and unsteady hydromagnetic waves

The effect of the magnetospheric MHD cavity on the excitation of the magnetosphere by stochastic and unsteady hydromagnetic waves incident from the solar wind is investigated theoretically by using a one-dimensional nonuniform model of the medium. It is shown that most of the energy of stochastic waves is reflected from the magnetopause and that the only waves that penetrate into the magnetosphere are those with frequencies in narrow spectral ranges near the eigenfrequencies of the cavity. These waves lead to steadystate excitation of the eigenmodes of the cavity, the energy of which is determined by the spectral density of the energy flux of the incident waves at the corresponding eigenfrequencies. The energy of the eigenmodes penetrates through the opacity barrier in the vicinity of the Alfvén resonance points (each corresponding to a particular mode), where the perturbation amplitude is sharply amplified, so the total energy localized close to the Alfvén resonance point is much higher than the total energy of the corresponding eigenmode. In the vicinities, the perturbation energy is dissipated by the finite conductivity of the ionosphere, the dissipation power being equal to the energy flux of the incident waves that penetrates into the magnetosphere. The case of unsteady waves is analyzed by considering a wave pulse as an example. It is shown that most of the energy of the wave pulse is reflected from the magnetopause. The portion of the incident perturbation that penetrates into the magnetosphere leads to unsteady excitation of the eigenmodes of the magnetospheric cavity, which are then slowly damped because part of the energy of the cavity is emitted through the magnetopause back to the solar wind while the other part penetrates into the vicinities of the Alfvén resonance points. In the vicinities, the perturbation is an Alfvén wave standing between magnetically conjugate ionospheres and its energy is dissipated by the finite conductivity of the ionosphere at a rate slower than the damping rate of the eigenmodes of the cavity.     

Resonance oscillations in the human arterial system]

The paper summarizes the results of the experiments aimed at obtaining sphygmograms of peripheral and carotid arteries with due regard to the values of longitudinal dimensions of body and extremities in healthy subjects. Mathematical equations expressing the fact that dicrotic waves recorded on sphygmograms are the reflections of blood eigentones coinciding with resonance oscillations have been derived. It is proved that at least two partial vibration systems oscillating with different own frequencies are present in human arteries. Conditions under which the resonance of constituent frequencies of pulsatile pressure waves and output waves in arteries occurs have been determined. From this point of view a new explanation for the well-known phenomenon of the pulsatile wave amplitude increase from the heart towards peripheric regions is proposed.     

Effect of low temperature on soybean peroxidase: spectroscopic characterization of the quantum-mechanically admixed spin state

A spectroscopic study of soybean peroxidase (SBP) has been carried out using electronic absorption, resonance Raman (RR) and electron paramagnetic resonance (EPR) spectroscopy in order to determine the effects of temperature on the heme spin state. Upon lowering the temperature a transition from high spin to low spin is induced in SBP resulting from conformational changes in the heme cavity, including a contraction of the heme core, the reorientation of the vinyl group in position 2 of the porphyrin macrocycle, and the binding of the distal His to the Fe atom. Moreover, the combined analysis of the data derived from the different techniques at both room and low temperatures demonstrates that at low temperature the quantum-mechanically admixed spin state (QS) of SBP has RR frequencies different from those observed for the QS species at room temperature.     

Real-Time Visualization of Joint Cavitation

Cracking sounds emitted from human synovial joints have been attributed historically to the sudden collapse of a cavitation bubble formed as articular surfaces are separated. Unfortunately, bubble collapse as the source of joint cracking is inconsistent with many physical phenomena that define the joint cracking phenomenon. Here we present direct evidence from real-time magnetic resonance imaging that the mechanism of joint cracking is related to cavity formation rather than bubble collapse. In this study, ten metacarpophalangeal joints were studied by inserting the finger of interest into a flexible tube tightened around a length of cable used to provide long-axis traction. Before and after traction, static 3D T1-weighted magnetic resonance images were acquired. During traction, rapid cine magnetic resonance images were obtained from the joint midline at a rate of 3.2 frames per second until the cracking event occurred. As traction forces increased, real-time cine magnetic resonance imaging demonstrated rapid cavity inception at the time of joint separation and sound production after which the resulting cavity remained visible. Our results offer direct experimental evidence that joint cracking is associated with cavity inception rather than collapse of a pre-existing bubble. These observations are consistent with tribonucleation, a known process where opposing surfaces resist separation until a critical point where they then separate rapidly creating sustained gas cavities. Observed previously in vitro, this is the first in-vivo macroscopic demonstration of tribonucleation and as such, provides a new theoretical framework to investigate health outcomes associated with joint cracking.     

On the dispersion properties of waveguides filled with a magnetized plasma

A study is made of the dispersion properties of waveguides filled with a magnetized plasma. It is shown that the eigenmodes of the waveguides filled with a low-density magnetized plasma fall into two families, which are weakly coupled to one another at all frequencies, in particular, in the cyclotron resonance frequency range. These families differ in transverse wavenumbers and the modes in them have hybrid polarization. Attention is focused on the study of the modes that have predominantly TE polarization at frequencies close to the cutoff frequency. The dependence of the critical frequencies of the TE modes on the plasma frequency, as well as the influence of the plasma on the energy flux and energy density of these modes, is investigated. The effect of mode crowding (the existence of an arbitrarily large number of dispersion curves in a finite frequency range between the cyclotron frequency and the upper hybrid frequency) is examined in detail. The results obtained are used to analyze how the plasma affects the electromagnetic properties of the cavity of the 1-MW 140-GHz continuous-wave gyrotron developed at the Institute of Pulsed and Microwave Technology of the Research Center in Karlsruhe, Germany (Institut für Hochleistungsimpuls-und Mikrowellentechnik Forschungszentrum Karlsruhe) for plasma heating in the W7-X stellarator, which is being constructed in Greifswald, Germany.     

The apparent mass of the seated human body: vertical vibration

Apparent mass frequency response functions of the seated human body have been measured with random vibration in the vertical direction at frequencies up to 20 Hz. A group of eight subjects was used to investigate some factors (footrest, backrest, posture, muscle tension, vibration magnitude) that may affect the apparent mass of a person; a group of 60 subjects (24 men, 24 women and 12 children) was used to investigate variability between people. Relative movement between the feet and the seat was found to affect the apparent mass at frequencies below resonance, particularly near zero-frequency. The resonance frequency generally increased with the use of a back rest, an erect posture and, in particular, increased muscle tension; but there was considerable intersubject variability in the changes. The magnitude of the vibration had a consistent effect: the resonance frequency decreased from about 6 to 4 Hz when the magnitude of the vibration was increased from 0.25 to 2.0 ms-2 r.m.s. The apparent masses of all the subjects were remarkably similar when normalized with respect to sitting weight. However, there were statistically significant correlations between apparent mass and some body characteristics (such as weight and age).     

Similar Spectral Power Densities Within the Schumann Resonance and a Large Population of Quantitative Electroencephalographic Profiles: Supportive Evidence for Koenig and Pobachenko

In 1954 and 1960 Koenig and his colleagues described the remarkable similarities of spectral power density profiles and patterns between the earth-ionosphere resonance and human brain activity which also share magnitudes for both electric field (mV/m) and magnetic field (pT) components. In 2006 Pobachenko and colleagues reported real time coherence between variations in the Schumann and brain activity spectra within the 6–16 Hz band for a small sample. We examined the ratios of the average potential differences (~3 μV) obtained by whole brain quantitative electroencephalography (QEEG) between rostral-caudal and left-right (hemispheric) comparisons of 238 measurements from 184 individuals over a 3.5 year period. Spectral densities for the rostral-caudal axis revealed a powerful peak at 10.25 Hz while the left-right peak was 1.95 Hz with beat-differences of ~7.5 to 8 Hz. When global cerebral measures were employed, the first (7–8 Hz), second (13–14 Hz) and third (19–20 Hz) harmonics of the Schumann resonances were discernable in averaged QEEG profiles in some but not all participants. The intensity of the endogenous Schumann resonance was related to the ‘best-of-fitness’ of the traditional 4-class microstate model. Additional measurements demonstrated real-time coherence for durations approximating microstates in spectral power density variations between Schumann frequencies measured in Sudbury, Canada and Cumiana, Italy with the QEEGs of local subjects. Our results confirm the measurements reported by earlier researchers that demonstrated unexpected similarities in the spectral patterns and strengths of electromagnetic fields generated by the human brain and the earth-ionospheric cavity.     

Resonance of Different Waveguide Structures with Various Vertical Indirect Coupled Cavities

In the paper, resonances of different waveguide structures with various vertical indirect coupled cavities were investigated by FDTD (finite difference-time domain). In the silicon cavity, Fano resonance could be observed at about 1430 nm. The coupling distance for the gold cavity/air cavity had less effect on the transmittance of the main waveguide but had a great influence on the transmission for water cavity in the visible region, which showed that water cavity could adjust resonance of waveguide structures. In addition, with the increment of refractive index n, the resonance peak at about 850 nm moved to the long wavelength (redshift). Dispersion rate about 2 × 10^–3/nm indicated that the transparent dielectric selectively absorbed the surface plasmon polariton wave and the sensitivity of the waveguide structure designed in this paper has high stability for the refractive index of the main waveguide cavity. Obvious Fano resonance could be observed with the increase of refractive index for silicon cavity. Among the four dielectrics, silicon and water are suitable for studying Fano resonance and filter dielectrics.

     

Effect of the distal residues on the vibrational modes of the Fe-CO bond in hemoglobin studied by protein engineering

Using an Escherichia coli gene expression system, we have engineered human hemoglobin (Hb) mutants having the distal histidine (E7) and valine (E11) residues replaced by other amino acids. The interaction between the mutated distal residues and bound carbon monoxide has been studied by Soret-excited resonance Raman spectroscopy. The replacement of Val-E11 by Ala, Leu, Ile, and Met has no effect on the v(C-O), v(Fe-CO) stretching or delta(Fe-C-O) bending frequencies in both the alpha and beta subunits of Hb, although some of these mutations affect the CO affinity as much as 40-fold. The strain imposed on the protein by the binding of CO is not localized in the Fe-CO bond and is probably distributed among many bonds in the globin. The replacement of His-E7 by Val or Gly brings the stretching frequencies v(Fe-CO) and v(C-O) close to those of free heme complexes. In contrast, the substitution of His-E7 by Gln, which is flexible and polar, produces no effects on the resonance Raman spectrum of either alpha- or beta-globin. The replacement of His-E7 of beta-globin by Phe shows the same effect as replacement by Gly or Val. Therefore, the steric bulk of the distal residues is not the primary determinant of the Fe-CO ligand vibrational frequencies. The ability of both histidine and glutamine to alter the v(C-O), v(Fe-CO), or delta(Fe-C-O) frequencies may be attributed to the polar nature of their side chains which can interact with bound CO in a similar manner.     

Domain-specific effector interactions within the central cavity of human adult hemoglobin in solution and in porous sol-gel matrices: evidence for long-range communication pathways

The water-filled central cavity of human adult hemoglobin (Hb A) is the binding or interaction site for many different allosteric effectors. Oxygen binding titrations reveal that pyrenetetrasulfonate (PyTS), a fluorescent analogue of 2,3-diphosphoglycerate, behaves like an allosteric effector. The ligation state, pH, and concentrations of other effectors (IHP, L35, and chloride) alter PyTS fluorescence for both solution-phase and sol-gel-encapsulated Hb samples. These conditions also alter the resonance Raman spectra and rates of geminate recombination of CO-ligated Hb. Together, these results demonstrate that there are conformational and functional consequences resulting from interactions between specific domains of the central cavity and individual effectors as well as from long-range synergistic effects that are mediated through the central cavity.     

Effect of an External Magnetic Field on the Absorption Efficiency of the RF Power in a Spatially Bounded Inductive Plasma Source

The measured dependences of the equivalent plasma resistance on the external magnetic field (0–50 G) in a 46-cm-diameter RF inductive plasma source operating at frequencies of 2, 4, and 13.56 MHz and a power of 100–500 W are presented. The experiments were carried out in argon at pressures of 0.1–30 mTorr. The presence of the external magnetic field leads to the appearance of resonance domains of efficient RF power absorption corresponding to the conditions of resonance excitation of helicons coupled with Trivelpiece–Gould modes. It is shown that RF power absorption at frequencies of 2 MHz can be optimized by applying an external magnetic field corresponding to the domains of resonance absorption. The effect is enhanced with increasing operating frequency.     

Poststenotic dilatation: arterial wall mechanics in response to vibration.

A study of the relationship between the mechanical response of human iliac arteries subjected to sinusoidally varying dynamic pressures superimposed on a static pressure of 100 mm Hg (1mm Hg = 133 N/m2) and the development of arterial dilatation, with particular reference to poststenotic dilatation has been conducted. In 13 experiments, optical measurements of the amplitude of vessel wall movements in response to dynamic pressures of amplitude 5 mm Hg peak to peak indicated the presence of at least one, and at most four resonance peaks for frequencies in the mean range 0-100 Hz. Four specimens were vibrated at resonance and four at frequencies 15 Hz higher than resonance, in response to a dynamic pressure of 5 mm Hg peak to peak for 3 h. All specimens exhibited some dilatation, the average percentage increase in diameter being in the range 0.22 to 0.42% per hour. In four additional experiments, the dynamic pressure was doubled at constant frequency. This resulted in an increased amplitude of vibration and additional dilatation at an increased rate. It is concluded that the dynamic stresses present in the vessel influence the rate of dilatation.     

人脑对不同频率穴位电刺激反应的功能性磁共振成像

利用功能性磁共振方法研究人脑对不同频率穴位体表电刺激（transcutaneous electric nerve stimulation,TENS)的反应。实验对11名志愿得进行了22次脑部功能性磁共振成像。成像过程中,每名志愿者分别接受了2和100HzTENS刺激,刺激部位为左腿足三里和三阴交穴,结果为不同频率TENS都激活了初级和次级躯体感觉区,频率特异性的激活信号出现在与运动相关的区域、丘脑、边缘系统和联络皮层。结果显示,在相同穴位给予不同频率的TENS要以在大脑引起不同的反应,提示2和100HzTENS可能激活了不同的神经通路,这些神经通路分别在中枢神经系统起着不同的作用。     

Resonance in the mouse tibia as a predictor of frequencies and locations of loading-induced bone formation

To enhance new bone formation for the treating of patients with osteopenia and osteoporosis, various mechanical loading regimens have been developed. Although a wide spectrum of loading frequencies is proposed in those regimens, a potential linkage between loading frequencies and locations of loading-induced bone formation is not well understood. In this study, we addressed a question: Does mechanical resonance play a role in frequency-dependent bone formation? If so, can the locations of enhanced bone formation be predicted through the modes of vibration? Our hypothesis is that mechanical loads applied at a frequency near the resonant frequencies enhance bone formation, specifically in areas that experience high principal strains. To test the hypothesis, we conducted axial tibia loading using low, medium, or high frequency to the mouse tibia, as well as finite element analysis. The experimental data demonstrated dependence of the maximum bone formation on location and frequency of loading. Samples loaded with the low-frequency waveform exhibited peak enhancement of bone formation in the proximal tibia, while the high-frequency waveform offered the greatest enhancement in the midshaft and distal sections. Furthermore, the observed dependence on loading frequencies was correlated to the principal strains in the first five resonance modes at 8.0–42.9 Hz. Collectively, the results suggest that resonance is a contributor to the frequencies and locations of maximum bone formation. Further investigation of the observed effects of resonance may lead to the prescribing of personalized mechanical loading treatments.     

Comparison of auditory functions in the chimpanzee and human

Absolute thresholds for pure tones, loudness, frequency and intensity difference thresholds and the resonance of the external auditory meatus were measured in chimpanzees and compared with those in humans. Chimpanzees were more sensitive than humans to frequencies higher than 8 kHz but less sensitive to frequencies lower than 250 Hz and 2- to 4-kHz tones. Difference thresholds for frequency and intensity were greater in chimpanzees than in humans. The resonance of the external ear was about the same in the two species. The effects of differences in hearing between species upon speech perception are discussed.     

Difference in frequency spectrum of extremely-low-frequency effects on the genome conformational state of AB1157 and EMG2 E. coli cells

The effect of weak extremely-low-frequency (ELF) magnetic fields (sinusoidal, 30 μT amplitude) on the genome conformational state (GCS) of E. coli mutant and wild type cells was studied by using the method of anomalous viscosity time dependency (AVTD) in the 6–37 Hz frequency range. We confirmed the existence of three resonance frequencies of 8.9, 15.5, and 29.4 Hz when mutant cells of K12 AB1157 strain were exposed. In the same frequency range, the wild type K12 EMG2 cells displayed only two effective windows, with resonance frequencies of 8.3 and 27 Hz. The resonance frequencies differed significantly (P < .001–.000001) in the strains studied, whereas other resonance parameters did not. It was concluded that mutations in the AB1157 strain resulted in a significant rearrangement in the ELF action spectrum, including the appearance of a new resonance. © 1996 Wiley-Liss, Inc.     

Frequency-dependent effects of ELF magnetic field on chromatin conformation in Escherichia coli cells and human lymphocytes.

The effects of magnetic fields of extremely low frequency (ELF, 21 microT r.m.s.) on cells of different Escherichia coli K12 strains and human lymphocytes were studied by the method of anomalous viscosity time dependence (AVTD). Within the frequency range of 6-24 Hz, two resonance-type frequency windows with maximal effects at 9 Hz and 16 Hz were observed in response of GE499 strain. Only one frequency window with maximum effect at 8.5 Hz was found for GE500 cells. These data along with previously obtained for two other E. coli strains, AB1157 and EMG2, indicate that frequency windows are dependent on genotype of cells exposed to ELF. Resonance-type effects of ELF were also observed in human lymphocytes in frequency windows around 8 and 58 Hz. These ELF effects differed significantly between studied donors, but were well reproducible in independent experiments with lymphocytes from the same donors. The frequency windows in response of E. coli strains and human lymphocytes to ELF significantly overlapped suggesting that the same targets may be involved in this response. We compared the frequency windows with predictions based on the ion cyclotron resonance (ICR) model and the magnetic parametric resonance model. These models predicted effects of ELF magnetic fields at the 'cyclotron' frequencies of some ions of biological relevance. According to the ICR model, ELF effects should be also observed at harmonics of cyclotron frequencies and, contrary, parametric resonance model predicted effects at subharmonics. While we observed coincidence of each experimental resonance frequency with predictions of one of these two models, all experimentally defined effective frequency windows were in good agreement with relatively narrow frequency ranges of both harmonics and subharmonics for natural isotopes of Na, K, Ca, Mg, and Zn ions. The experimental data support idea that both harmonics and subharmonics of several biologically important ions are involved in frequency-dependent ELF effects in cells of different types.     

Proton nuclear magnetic resonance investigation of the allosteric transition in ligated and unligated carp hemoglobin. Evidence for structural heterogeneity in the heme pocket

The proton nuclear magnetic resonance spectra of carp hemoglobin (Hb) in the unligated deoxy and ligated met-cyano and met-azido forms have been recorded as a function of pH and upon addition of inositol hexaphosphate. All protein derivatives yield spectra that are consistent with appreciable molecular heterogeneity in the heme cavity. The pattern of heme methyl hyperfine shifts in carp met-cyano Hb indicates that this heterogeneity arises from the presence of heme rotational disorder, as found in native myoglobin. In carp deoxy Hb, the T----R transition manifests itself in nuclear magnetic resonance spectral changes similar to those found in modified human Hb species; namely, a decrease in heme methyl and an increase in proximal histidyl imidazole ring NH hyperfine shifts indicative of a strengthening of the iron-histidine bond. The met-cyano complex exhibits heme methyl hyperfine shifts similar to the analogous R state complex of Hb A; addition of inositol hexaphosphate did not give evidence for a quaternary structural change. Carp met-azido Hb in the R state also closely resembles the electronic structure of the HbA complex. Addition of inositol hexaphosphate appeared to effect at least a partial conversion to a T state with larger high-spin content than that observed for T state human metHbN3.