共查询到20条相似文献,搜索用时 15 毫秒
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Hahn S 《Nature structural & molecular biology》2004,11(5):394-403
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Ebright RH 《Journal of molecular biology》2000,304(5):687-698
Bacterial RNA polymerase and eukaryotic RNA polymerase II exhibit striking structural similarities, including similarities in overall structure, relative positions of subunits, relative positions of functional determinants, and structures and folding topologies of subunits. These structural similarities are paralleled by similarities in mechanisms of interaction with DNA. 相似文献
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Tails of RNA polymerase II 总被引:35,自引:0,他引:35
J L Corden 《Trends in biochemical sciences》1990,15(10):383-387
Eukaryotic RNA polymerase II contains two distinct structural domains: a catalytic core consisting of subunits that are homologous to other multisubunit RNA polymerases, and a unique extension of the carboxy-terminus of the largest subunit comprising tandem repeats of the seven amino acid sequence YSPTSPS. This repetitive 'tail' domain is essential for polymerase function in vivo. Although the nature of this essential function is unknown, actively transcribing RNA polymerase II is known to be multiphosphorylated on this repetitive domain. 相似文献
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The Mediator of RNA polymerase II 总被引:7,自引:0,他引:7
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