Plant-pollinator interactions: from specialization to generalization * Waser NM, Ollerton J. eds. 2006. * Chicago: Chicago: The University of Chicago Press. $45 (paperback). 488 pp.

Highly specializedpollination systems, such as figs and their wasp or orchidsthat deceive bees in trying to make them mate with their floralorgans, are intuitively appealing to most people and have, therefore,gained far more attention both in popular and scientific literaturethan the more generalized pollination systems. For a long timethe dominant view was that many, or perhaps even most, plant–pollinatorinteractions were specialized. In 1996 Waser and his colleaguestried to stir things up by writing an article in which theyargued that, in contrast to common belief, generalization waswidespread in plant–pollinator systems. Ten     

Indirect allosteric effects of a neutral mutation. Structure of deoxyhaemoglobin north Chicago (ProC2(36)beta----Ser)

Haemoglobin North Chicago (ProC2(36 beta----Ser) has an abnormally high oxygen affinity. A survey of other abnormal human haemoglobins with high oxygen affinity has indicated that mutations leading to a cavity in the quaternary T-structure, or to the rupture of any bond in that structure, have raised oxygen affinities, because such mutations loosen the constraints of the T-structure. They do not usually affect the oxygen affinity of the R-structure. Haemoglobin North Chicago aroused our interest because the side-chain of serine is smaller than that of proline by only one carbon atom, and it was hard to conceive how such a small gap should raise the oxygen affinity significantly. Our X-ray study shows that the mutation produces unexpectedly large indirect changes in the T-structure.