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1.
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2.
Twelve of the main European LCA software packages currently available are examined wirh the aim of establishing which are the most appropriate for LCAs on industrial processes. The packages performances are assessed in terms of
–  • Volume of Data
–  • WindowsTM environment
–  • Network Capabilities
–  • Impact Assessment
–  • Graphical representation of the inventory results
–  • Sensitivity analysis
–  • Units
–  • Cost
–  • User Support
–  • Flow Diagrams
–  • Burdens allocation
–  • Transparency of data
–  • Input & output parameters
–  • Demo version
–  • Quality of data
The review concludes with a Specification Table which summarises the facilities available on each software package. The general conclusion from this study is that for industrially based LCAs, there are four packages which may offer advantages over the rest. These are The Boustead Model, The Ecobilan Group’s TEAM™, PEMS 3.0 and SimaPro 3.1.  相似文献   

3.
J. Robb 《Human Evolution》1994,9(3):215-229
In recent years anthropologists have made much progress in understanding ancient activities from skeletal remains. In this paper, material from the Iron Age cemetery at Pontecagnano (VII-IV century BC) is used to illustrate activity-related traits of eight basic categories:
(1)  idiosyncratic patterns of dental wear
(2)  activity-related articular degeneration
(3)  non-pathological functional alterations (neoformations, contact facets)
(4)  mechanical remodelling of bone architecture
(5)  enthesopathies (muscular lesions)
(6)  traumatic lesions
(7)  activity-related pathologies
(8)  activity-related nutritional characteristics
These traits, and others, can be used not only singly but in conjunction to define (a) patterns of activity and occupational specialization for individuals, and (b) distributions within society reflecting the basic division of labor by geneder and class.  相似文献   

4.
G. Rombi  G. Piu  S. Piro  V. Anedda 《Cytotechnology》1993,11(Z1):S147-S149
Being able to carry zidovudine (AZT) at known concentrations into CD4+/CD38+ and CD14+ cells permits:
–  - to reduce the drug dosage and to increase the interval for administration (until 1 dose I.V. every week);
–  - to modulate the drug concentration into the CD4+/CD38 an CD14+ cells in relation to the in vitro determined HIV sensitiveness;
–  - to eliminate haematological, medullary and general toxicity;
–  - to be able to treat severely hill patients.
Further studies are necessary in order to:
–  - To find out the better phase to start the therapy;
–  - To use several drugs with different mechanisms of action in order to slow down as much as possible the presence of resistant viral strains.
–  - As for other drugs which are beginning to be used with artificial vehicles, futher studies are required to improve the selectivity and safety of LIPOAZT for the target cells including macrophages.
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5.
Cannibalism in teleost fish   总被引：1，自引：0，他引：1  
1.  Cannibalistic behaviour in fish is reviewed here for the first time.
2.  Cannibalism has been recorded in 36 out of 410 teleost families according to the published literature, but is considered to be more widespread than this. Finding examples of cannibalism is not difficult, and it may be more interesting to look for taxa in which the behaviour does not take place.
3.  The families that have provided the most information include the Engraulididae, Esocidae, Poeciliidae, Gasterosteidae, Percidae and Cichlidae.
4.  Cannibalism has been classified into seven types, depending on life-history stage, age difference between cannibal and prey, and whether or not they are related.
5.  Although in captive populations, cannibalism tends to increase with increasing density and decreasing food availability, its role in population regulation has not been unequivocally demonstrated in any wild population, and obtaining the necessary data presents a formidable challenge to fish ecologists.
6.  Cannibalism is of some economic importance in aquaculture, but its impact can be reduced relatively easily, by frequent grading to reduce size variability.
7.  The main proximate advantage conferred by cannibalism is assumed to be nutritional. In an ultimate sense the behaviour may have evolved as a particularly effective competitive strategy.
8.  Finally, it is considered that cannibalism deserves more attention from fish biologists. Investigations, however, should recognize the different types of cannibalistic interaction, and, in particular, should explore the different implications of kin and nonkin cannibalism
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6.
Oncostatin M, a multifunctional cytokine   总被引：6，自引：0，他引：6  
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7.
1.  Paramecium bursaria was stimulated by a light spot of 10–15 m diameter, and the photosensitive site was searched by recording responses in swimming behavior and in membrane potential.
2.  Local stimulation to the anterior half of the cell caused an avoiding response.
3.  Stimulation to the cells deciliated by ethanol treatment elicited a depolarization of the membrane potential.
4.  Local stimulation to the anteroventral portion elicited a depolarization, but stimulation to the dorsal side induced no change in the membrane potential.
5.  The action spectrum of depolarization elicited by local stimulation to the anteroventral surface showed two main peaks at 420 nm and 560 nm, corresponding to those of light stimulation of the whole cell.
6.  It is concluded that a photosensitive site exists on the anteroventral surface ofParamecium, in particular within the oral groove of the cell. This local photosensitivity is discussed with respect to the mating reaction.
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8.
1.  At 28°C conversion efficiency of total nitrogen (TN) was inversely related to size.
2.  In the pre-adult stage protein nitrogen (PN) conversion efficiency was high whereas in the Post-adult stage non-protein nitrogen (NPN) conversion efficiency was high.
3.  Lower temperature (20°C) was not congenial for PN conversion.
4.  Higher temperature favoured PN conversion for smaller fish but NPN for larger fish.
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9.
Thiolutin was found to inhibit the utilization of glucose and other growth substrates in Escherichia coli. The inhibition was detected by a sharp drop of the respiration rate after addition of the antibiotic. The actual function affected was allocated to the cytoplasmic membrane of the bacterial cells by the following evidence:
–  - spheroplasts were affected like intact cells,
–  - individual reactions of either the electron transport chain or the glycolytic pathway were not inhibited,
–  - glucose consumption in the culture stopped and the cells accumulated guanosine tetraphosphate as under starvation conditions,
–  - activation of the cell's apo-glucose dehydrogenase restored respiration via bypassing the glucose phosphotransferase system.
It was concluded that the transport of certain substrates across the membrane was inhibited.  相似文献   

10.
3DFS is a 3D flexible searching system for lead discovery. Version 1.0 of 3DFS was published recently (Wang, T.; Zhou, J. J. Chem. Inf. Comput. Sci., 1998, 38, 71–77). Here version 1.2 represents a substantial improvement over version 1.0. There are six major changes in version 1.2 compared to version 1.0.
1.  A new rule of aromatic ring recognition.
2.  The inclusion of multiple-type atoms and chains in queries.
3.  The inclusion of more spatial constraints, especially the directions of lone pairs.
4.  The improvement of the query file format.
5.  The addition of genetic search for flexible search.
6.  An output option for generating MOLfiles of hits.
Besides the above, this paper supplies:
1.  More query examples.
2.  A comparison between genetic search and Powell optimization.
3.  More detailed comparison between 3DFS and Chem-X.
4.  A preliminary application of 3DFS to K+ channel opener studies.
Supplementary material to this paper is available in electronic form at http://dx.doi.org/10.1007/s0089490050231  相似文献   

11.
Conclusions  
(1)  The aminoesters inhibit glucose-stimulated proton extrusion by yeast cells.
(2)  The inhibitory activity depends on aliphatic carbon chain length.
(3)  The inhibition of proton extrusion is concentration-dependent.
(4)  The aminoesters stimulate quinacrine accumulation in vacuoles of yeast cells so they should possess affinities for lysosomes.
This work was supported byKBN grant no. 7 A203 013 07.  相似文献   

12.
1.  The overall rate of feeding at 28°C bears an inverse relationship to size; the time course of feeding appears to be size-independent and shows a decline with increase in time.
2.  Absorption efficiency is independent of size.
3.  The rates of absorption and conversion and conversion efficiency are inversely related to size.
4.  The rate of feeding is reflected on the rates of absorption and conversion.
  相似文献   

13.
In the rift valley (North-East of France/South-West of Germany), the Rhine runs freely for 300 km from South to North. The absence of natural obstacles allows the development of a very regular profile of the river. We have therefore an opportunity to study very gradual modifications of the alluvial forest communities of the fluvial corridor from upstream to downstream, according to the gradual evolution of the ecological factors, related to slope decrease and hydrological modifications.We describe, from Basel to Mainz:
1)  modification of dynamic processes in the forest communities such as successional sequences or sylvigenetic mosaïcs of the terminal stages.
2)  modification of species richness.
3)  reduction of species diversity.
4)  simplification of the forest stratification.
5)  modification of efficiency of the biogeochemical cycling.
6)  ecological vicariances.
7)  modification in species behaviour.
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14.
Summary  
1.  The phenotype of the ‘assimilated bithorax’ stock is due in part to a number of genes, on all the chromosomes, which act directly on the individuals containing them, and partly to a recessive X-chromosome condition which causes a maternal effect.
2.  Attempts to break down the maternal-effect condition by crossing-over were unsuccessful.
3.  The maternal effect condition, when made homozygous in a wild-type background, causes the appearance of some bithoraxes in the next generation.
4.  The condition may have arisen by mutation during the course of the selection by which the assimilated stock was built up, but it may have been present in very low frequency in the initial population.
5.  The offspring of females homozygous for the maternal-effect condition do not produce a higher percentage of bithoraxes, following ether treatment, than do flies of similar genotype from other mothers.
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15.
1.  The reactions of tympanic nerve fibers ofLocusta migratoria were recorded by glass microelectrodes in the metathoracic ganglion.
2.  The units were classified by frequency-, intensity-, and directional characteristics as well as by their response pattern. The response to speciesspecific song is compared with the response to song ofEphippiger ephippiger.
3.  The physiological properties lead to a classification into three types of low-frequency neurons (characteristic frequency 3.5–4 kHz; 4kHz; 5.5–6 kHz) and one type of high-frequency neuron (12–20 kHz). This is similar to other species (Gray, 1960, Michelsen, 1971).
4.  Intensity-coding is done by sharp rising intensity characteristics and by different absolute thresholds of the units.
5.  There is a marked directional sensitivity with some differences between LF and HF units. In the low frequency range the tympanal organ seems to react as a pressure gradient receiver; for high frequencies another mechanism is discussed.
6.  No filtering of species-specific song takes place at the level of the receptor cells.
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16.
1.  Properties of the membrane currents ofDidinium nasutum have been investigated under voltage clamp in different solutions and after deciliation.
2.  Theearly transient Ca2+ inward current activates in a voltage-dependent manner. Inactivation is both Ca2+ -dependent and voltage-dependent.
3.  Alate Ca2+ current rises with time to peak > 50 ms and decays in the order of seconds.
4.  Activation and inactivation of the late Ca2+ current is voltage-dependent.
5.  The delayed outward current is activated by voltage. The kinetics of this K+ current, but not its amplitude, are enhanced in the presence of intracellular EGTA.
6.  The two voltage-dependent Ca2+ channels are located in the cilia, whereas all K+ channels are restricted to the somatic membrane.
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17.
Müller  D. G.  Frenzer  K. 《Hydrobiologia》1993,(1):37-44
Culture studies with healthy and virus-infected isolates of Ectocarpus siliculosus, Feldmannia simplex and F. irregularis gave the following results:
–  Virus particles are produced in deformed reproductive organs (sporangia or gametangia) of the hosts and are released into the surrounding seawater.
–  Their infective potential is lost after several days of storage under laboratory conditions.
–  New infections occur when gametes or spores of the host get in contact with virus particles. The virus genome enters all cells of the developing new plant via mitosis.
–  Virus expression is variable, and in many cases the viability of the host is not impaired. Infected host plants may be partly fertile and pass the infection to their daughter plants.
–  Meiosis of the host can eliminate the virus genome and generate healthy progeny.
–  The genome of the Ectocarpus virus consists of dsDNA. Meiotic segregation patterns suggest an intimate association between virus genome and host chromosomes.
–  An extra-generic host range has been demonstrated for the Ectocarpus virus.
–  Field observations suggest that virus infections in ectocarpalean algae occur on all coasts of the world, and many or all Ectocarpus and Feldmannia populations are subject to contact with virus genomes.
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18.
(1)  The inactivation of various forms of nucleoside transport with reagents blocking thiol groups was studied in whole cells ofE. coli B. No positive correlation between the efficiency of active transport and the extent or rate of inactivation could be demonstrated.
(2)  The most efficient constitutive nucleoside-transporting system was found to comprise a specific thiol component characterized by low rate of inactivation with N-ethylmaleimide; the less efficient inducible transport and the facilitated diffusion of guanosine require the integrity of another thiol component which is rapidly inactivated with N-ethylmaleimide.
(3)  The constitutive nucleoside-transporting system is completely inactivated with T4 phage, while other modes of nucleoside transport are much less affected.
(4)  Inactivation of constitutive transporting system in cells exposed to N-ethylmaleimide for a limited period of time continues long after the inhibitor has been removed, indicating storage of the inhibitor in some cellular compartment. Addition of dithiothreitol stops the inactivation immediately.
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19.
1.  We used laser vibrometry and free field sound stimulation to study the frequency responses of the eardrum and the lateral body wall of awake male Eleutherodactylus coqui.
2.  The eardrum snowed one of two distinct frequency responses depending on whether the glottis was open (GO response) or closed (GC response) during the measurement.
3.  The lateral body wall vibrated with a maximum amplitude close to that of the eardrum and in the same frequency range.
4.  Covering the frog's body wall with vaseline reduced the vibration amplitude of the GC response by up to 15 dB.
5.  When a closed sound delivery system was used to stimulate a local area of the body wall the eardrum also showed one of two types of responses.
6.  These results suggest that sound is transmitted via the lung cavity to the internal surface of the eardrum. This lung input has a significant influence on the vibrations of the eardrum even when the glottis is closed.
7.  The vibration amplitude of the eardrum changed with the angle of sound incidence. The directionality was most pronounced in a narrow frequency range between the two main frequencies of the conspecific advertisement call.
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20.
1.  An extracellular recording and staining technique has been used to study the structure of individual ventral-cord elements in the auditory pathway ofLocusta migratoria.
2.  Three groups of auditory ventral-cord neurons can be distinguished: (a) neurons ascending to the supraesophageal ganglion, (b) T-shaped neurons, and (c) neurons limited to the thoracic ventral cord.
3.  The ventral-cord neurons ascending to the supraesophageal ganglion link the auditory centers of the thorax to those of the supraesophageal ganglion. These are, at least in part, richly arborized neurons of large diameter.
4.  The ventral-cord neurons with T structure send equivalent signals along both arms of the T; they resemble the neurons of the first group in that they make synaptic connections in the supraesophageal ganglion, but they also conduct auditory information to caudal regions of the thorax via the descending trunk of the axon.
5.  In the supraesophageal ganglion there are several extensive projection areas of the auditory ventral-cord neurons. No direct connections to the mushroom bodies, the central body or the protocerebral bridge could be demonstrated.
6.  The thoracic ventral-cord neurons act as short segmental interneurons, providing a connection between the tympanal receptor fibers and the ascending and T-shaped ventral-cord neurons. They play a crucial role in auditory information processing.
7.  The possible functional properties of the various morphological sections of the auditory ventral-cord neurons are discussed, with reference to their connections with motor and other neuronal systems.
  相似文献   

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