Indications de la TEP-FDG en oncologie. Mise à jour selon les recommandations de prise en charge européennes et américaines

[18F]-Fluoro-2-Deoxy-D-Glucose-Positon Emission Tomography (PET) is a powerful tool which availability increases in France. The oncological PET indications are plentiful and are increasing. Yet, its cost is significant. Thus, it is important to use PET in validated indications and/or in situations in which it can improve the patient management. The first part of this work reviews the PET indications in oncology, according to the international clinical practice guidelines (European Society for Medical Oncology [ESMO] and National Comprehensive Cancer Network [NCCN]), and compares those with the French guidelines (Guide de bon usage [GBU] des examens d’imagerie médicale). The second part assesses the indication distribution of 400 consecutive PET-CT studies in an against cancer center, according to the cancer type and confronts those with the guidelines.     

Répartiteur de dose des médicaments radiopharmaceutiques : contrôle qualité sur deux sites hospitaliers et comparaison avec la législation en vigueur en France

An increasing number of nuclear medicine departments are equipped with automated measurement systems for the preparation of radiopharmaceuticals, with the main aim of minimising technician's irradiation. However, the automatic measurement of the patient activity differs from the manual measurement in material and method. In this context, the objective of the present study was to test the performances of one of these systems, the Unidose by TRASIS^®, in two newly equipped hospitals. The particularity of these systems is they are made up of two dose calibrators: the entrance calibrator (well chamber) and the exit calibrator (probe). Controls were performed on both of these dose calibrators. The results obtained, as well as the methodology employed, were then compared with the regulatory requirements in France. The results found are coherent between the two sites and have highlighted several non-conformities compared to the current regulations, part of which concerning the carpule dose calibrator, which is actually a probe. These results raise the question of a suitable regulation for the new automated measurement systems in nuclear medicine.     

Facteurs de croissance et vitamines chez les plantes. Recherches sur l'action des extraits d'Aspergillus sur le développement de Phycomyces

Sans résumé     

Première expérimentation écologique sur les Entomophthorales (Phycomycètes) parasites de pucerons en vergers de pêchers

Résumé Un essai infructueux d'implantation de l'entomophthorose dans une population deMyzus persicae en verger de Pêcher a révélé les principales difficultés inhérentes à ce genre d'expérimentation écologique où l'apport d'inoculum est accompagné d'une tentative de modification du milieu par des aspersions contr?lées. L'épizootiologie de l'entomophthorose dans les vergers de la vallée du Rh?ne est discutée en fonction de la fréquence des jours pendant lesquels l'humidité relative demeure élevée pendant plus de 12 heures et la température maximale excède 20°C.

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Summary A preliminary experiment has been undertaken in May 1970 in the Rhone Valley in order to implant focuses ofEntomophthora aphidis Hoffm. andE. thaxteriana Petch. in colonies ofMyzus persicae Sulz. and to study the effect of sprinkling. The aim of the sprinkling is to provide the presence of a continuous film of water on the leaves of the trees during the delay (8 to 14 hours) required by the critical phase of the cycle of the pathogen (sporulation-infection). Four plots were considered: The check-plot without inoculum or sprinkling, a plot with inoculum but without sprinkling, a plot with sprinkling but without inoculum and the fourth plot with inoculum and sprinkling. By an extra infestation, an homogenous population has been established on the 6 trees of each plot. The inoculum consists partly in cultures of the fungous in Petri dishes, partly in dead aphids in the phase of projection of conidia. The failure of the experiment is attributed to the very quick destruction of the inoculum by sorching winds, to the working-failure of the sprinkling system and specially to the adversity of the climatic conditions during the last decade of May (no diurnal rains, high frequency of windy days). The epizootiology of Entomophthorales in orchards of the Rhone Valley is discussed at light of the frequence of the days with high relative humidity during more than 12 hours and that of the days with maximal temperatures exceeding 20°C.

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Communication présentée à la 2^e réunion du groupe de travail PBI ?Biological Control of Aphids?, Paris, 16–18 septembre 1970.