Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs

1. Download : Download high-res image (333KB)
2. Download : Download full-size image

     

Dux-Mediated Corrections of Aberrant H3K9ac during 2-Cell Genome Activation Optimize Efficiency of Somatic Cell Nuclear Transfer

1. Download : Download high-res image (144KB)
2. Download : Download full-size image

     

Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility

1. Download : Download high-res image (253KB)
2. Download : Download full-size image

     

FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

1. Download : Download high-res image (153KB)
2. Download : Download full-size image

     

HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases

1. Download : Download high-res image (234KB)
2. Download : Download full-size image

     

A lncRNA fine-tunes salicylic acid biosynthesis to balance plant immunity and growth

1. Download : Download high-res image (220KB)
2. Download : Download full-size image

     

Bacterial infection reinforces host metabolic flux from arginine to spermine for NLRP3 inflammasome evasion

1. Download : Download high-res image (216KB)
2. Download : Download full-size image

     

Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring

1. Download : Download high-res image (157KB)
2. Download : Download full-size image

     

Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks

1. Download : Download high-res image (175KB)
2. Download : Download full-size image

     

Histone H3K79 methylation by DOT1L promotes Aurora B localization at centromeres in mitosis

1. Download : Download high-res image (192KB)
2. Download : Download full-size image

     

Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response

1. Download : Download high-res image (179KB)
2. Download : Download full-size image

     

Defining How Oncogenic and Developmental Mutations of PIK3R1 Alter the Regulation of Class IA Phosphoinositide 3-Kinases

1. Download : Download high-res image (148KB)
2. Download : Download full-size image

     

Simultaneous profiling of multiple chromatin proteins in the same cells

1. Download : Download high-res image (234KB)
2. Download : Download full-size image

     

CpG island reconfiguration for the establishment and synchronization of polycomb functions upon exit from naive pluripotency

1. Download : Download high-res image (223KB)
2. Download : Download full-size image

     

Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis

1. Download : Download high-res image (119KB)
2. Download : Download full-size image

     

Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis

1. Download : Download high-res image (368KB)
2. Download : Download full-size image

     

Dynamic BMP signaling mediates notochord segmentation in zebrafish

1. Download : Download high-res image (192KB)
2. Download : Download full-size image

     

Stage-specific H3K9me3 occupancy ensures retrotransposon silencing in human pre-implantation embryos

1. Download : Download high-res image (177KB)
2. Download : Download full-size image

     

Bipartite binding of the N terminus of Skp2 to cyclin A

1. Download : Download high-res image (148KB)
2. Download : Download full-size image

     

Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells

1. Download : Download high-res image (114KB)
2. Download : Download full-size image