共查询到20条相似文献,搜索用时 15 毫秒
1.
Nafiu Amidu William KBA Owiredu Eric Woode Otchere Addai-Mensah Lawrence Quaye Abass Alhassan Edmond A Tagoe 《Reproductive biology and endocrinology : RB&E》2010,8(1):106
Background
Sexuality is a complex phenomenon that is being influenced by psychological as well as physiological factors. Its dysfunction includes desire, arousal, orgasmic and sex pain disorders. The present study aimed to assess the incidence of sexual dysfunction (SD) and related risk factors in a cohort of Ghanaian women. 相似文献2.
Background
Autonomic nervous system (ANS) dysfunction is present in up to one third of patients with tetanus. The prognostic value of ANS dysfunction is known in severe tetanus but its value is not well established in mild to moderate tetanus. 相似文献3.
Sven H Stüwe Oliver Goetze Larissa Arning Matthias Banasch Wolfgang E Schmidt Ludger Schöls Carsten Saft 《BMC neurology》2011,11(1):145
Background
Mitochondrial dysfunction due to respiratory chain impairment is a key feature in pathogenesis of Friedreich ataxia. Friedreich ataxia affects the nervous system, heart and pancreas. 相似文献4.
Alberto Revelli Simona Casano Delle Luisa Piane Giuseppina Grassi Gianluca Gennarelli Daniela Guidetti Marco Massobrio 《Reproductive biology and endocrinology : RB&E》2009,7(1):137-6
Background
Anti-thyroid antibodies (ATA), even if not associated with thyroid dysfunction, are suspected to cause poorer outcome of in vitro fertilization (IVF). 相似文献5.
Introduction
Sentinel lymph nodes (SLNs) of melanoma patients show evidence of tumor-induced immune dysfunction. Our previous works have shown that IL-10 and IFNγ co-regulate indoleamine-2,3-dioxygenase (IDO)-expressing immunosuppressive dendritic cells (DCs) in melanoma SLNs. The goal of this study is to examine the relationship between melanoma SLN tumor burden and the degree of SLN immune dysfunction as a model to study tumor-induced immune dysfunction. We hypothesize that SLN tumor burden correlates with the degree of SLN immune dysfunction. 相似文献6.
Background
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder associated with ovulatory dysfunction, abdominal obesity, hyperandrogenism, hypertension, and insulin resistance. 相似文献7.
Background
The brain-derived protein S100B has been shown to be a useful marker of brain injury of different etiologies. Cognitive dysfunction after cardiac surgery using cardiopulmonary bypass has been reported to occur in up to 70% of patients. In this study we tried to evaluate S100B as a marker for cognitive dysfunction after coronary bypass surgery with cardiopulmonary bypass in a model where the inflow of S100B from shed mediastinal blood was corrected for. 相似文献8.
Ingeborg Bosma Jaap C Reijneveld Martin Klein Linda Douw Bob W van Dijk Jan J Heimans Cornelis J Stam 《Nonlinear biomedical physics》2009,3(1):9-11
Background
To understand neurophysiological mechanisms underlying cognitive dysfunction in low-grade glioma (LGG) patients by evaluating the spatial structure of 'resting-state' brain networks with graph theory. 相似文献9.
Marieke Biegstraaten Ivo N van Schaik Wouter Wieling Frits A Wijburg Carla EM Hollak 《BMC neurology》2010,10(1):38
Background
Fabry patients have symptoms and signs compatible with autonomic dysfunction. These symptoms and signs are considered to be due to impairment of the peripheral nervous system, but findings indicative of autonomic neuropathy in other diseases, such as orthostatic intolerance and male sexual dysfunction, are infrequently reported in Fabry disease. The aim of our study was to investigate autonomic symptoms and cardiovascular autonomic function in a large cohort of male and female Fabry patients. 相似文献10.
Background
Migraine has been associated with cardiovascular disorders. Endothelial dysfunction may be a mechanism underlying this association. The present study tested the hypothesis that endothelium-dependent vasodilation, basal endothelial nitric oxide release and endothelial fibrinolytic capacity are impaired in migraine patients. 相似文献11.
Pal Soltesz Daniel Bereczki Peter Szodoray Maria T Magyar Henrietta Der Istvan Csipo Agota Hajas Gyorgy Paragh Gyula Szegedi Edit Bodolay 《Arthritis research & therapy》2010,12(3):R78
Introduction
The aim of the present study was to investigate the association between cardiovascular risk factors and endothelial dysfunction in patients with mixed connective tissue disease (MCTD) and to determine which biomarkers are associated with atherosclerotic complications, such as cardiovascular disease. 相似文献12.
Fin ZJ Cai Sue Lester Tim Lu Helen Keen Karyn Boundy Susanna M Proudman Anne Tonkin Maureen Rischmueller 《Arthritis research & therapy》2008,10(2):R31
Introduction
The aim of this study was to compare cardiovascular autonomic nervous system function in patients with primary Sj?gren's syndrome (pSS) with that in control individuals, and to correlate the findings with autonomic symptoms and the presence of exocrine secretory dysfunction. 相似文献13.
Oliver Löwenstein Petra Leyendecker Eberhard A Lux Mark Blagden Karen H Simpson Michael Hopp Björn Bosse Karen Reimer 《BMC clinical pharmacology》2010,10(1):12
Background
Two randomised 12-week, double-blind, parallel-group, multicenter studies comparing oxycodone PR/naloxone PR and oxycodone PR alone on symptoms of opioid-induced bowel dysfunction in patients with moderate/severe non-malignant pain have been conducted. 相似文献14.
Kristin Andreas Thomas Häupl Carsten Lübke Jochen Ringe Lars Morawietz Anja Wachtel Michael Sittinger Christian Kaps 《Arthritis research & therapy》2009,11(1):R15-14
Introduction
Rheumatoid arthritis (RA) leads to progressive destruction of articular cartilage. This study aimed to disclose major mechanisms of antirheumatic drug action on human chondrocytes and to reveal marker and pharmacological target genes that are involved in cartilage dysfunction and regeneration. 相似文献15.
Clifford DL Folmes Grzegorz Sawicki Virgilio JJ Cadete Grant Masson Amy J Barr Gary D Lopaschuk 《Proteome science》2010,8(1):38
Background
During and following myocardial ischemia, glucose oxidation rates are low and fatty acids dominate as a source of oxidative metabolism. This metabolic phenotype is associated with contractile dysfunction during reperfusion. To determine the mechanism of this reliance on fatty acid oxidation as a source of ATP generation, a functional proteomics approach was utilized. 相似文献16.
Vilmante Borutaite Ramune Morkuniene Odeta Arandarcikaite Aiste Jekabsone Jurgita Barauskaite Guy C Brown 《Journal of biomedical science》2009,16(1):70-12
Background
Heart ischemia can rapidly induce apoptosis and mitochondrial dysfunction via mitochondrial permeability transition-induced cytochrome c release. We tested whether nitric oxide (NO) can block this damage in isolated rat heart, and, if so, by what mechanisms. 相似文献17.
Background
Chronic Fatigue Syndrome (CFS), Persian Gulf War Illness (PGI), and fibromyalgia are overlapping symptom complexes without objective markers or known pathophysiology. Neurological dysfunction is common. We assessed cerebrospinal fluid to find proteins that were differentially expressed in this CFS-spectrum of illnesses compared to control subjects. 相似文献18.
Sarah S Knox 《Cancer cell international》2010,10(1):11
Background
Cancer is a complex disease that involves a sequence of gene-environment interactions in a progressive process that cannot occur without dysfunction in multiple systems, including DNA repair, apoptotic and immune functions. Epigenetic mechanisms, responding to numerous internal and external cues in a dynamic ongoing exchange, play a key role in mediating environmental influences on gene expression and tumor development. 相似文献19.
Daniel M Canafax Abhijeet Bhanegaonkar Murtuza Bharmal Michael Calloway 《BMC neurology》2011,11(1):48
Background
Because of the subjective nature of Restless Legs Syndrome (RLS) symptoms and the impact of these symptoms on sleep, patient-reported outcomes (PROs) play a prominent role as study endpoints in clinical trials investigating RLS treatments. The objective of this study was to validate a new measure, the Post Sleep Questionnaire (PSQ), to assess sleep dysfunction in subjects with moderate-to-severe RLS symptoms. 相似文献20.
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