Just Choices: Representations of Choice and Coercion in Sex Work in Cambodia

In global discourses about sex work, the image of the ‘sex slave’ has been influential in constructing the view of women working in the sex industry in developing countries as ‘victims’. This paper examines the perpetuation of such discourses through powerful lobbying groups and socially conservative governments. It argues that frameworks that situate women working in the Cambodian sex industry through a singular identity of ‘victim’ or ‘agent’ are inadequate in informing our understandings of sex work in the country. Based on ethnographic research and interviews with sex workers in the port city of Sihanoukville, Cambodia, this paper questions prevailing stereotypes of ‘trafficking victims' and the image of ‘defiled’ or ‘duped’ women and girls central to such frameworks. It examines the intricate intertwining of elements of individual choice and coercion in women's lives and illuminates how, in the transition to a market economy, women's choices are constrained by hierarchal structures such as gender, class and socio‐cultural obligations and poor employment opportunities.     

Telling the forest from the trees: Local images of national change in a Danish town

How can ethnographers see the ‘big picture’, while they are busy with everyday minutiae? Awareness of the local impacts of history and globalisation has revived debates about the pragmatics of fieldwork. Arguing that most fieldwork remains, for most practitioners, ‘local’, this paper explores how it is possible to apprehend change ethnographically. Something of how local people understand and experience change, as it happens to them and around them and as they contribute to it, can be grasped in ‘significant local imagery’, in this case, ‘significant people’, ‘significant things’, and ‘significant events’. These images are recognised in local discourse as indicative or ‘telling’ of change, and can be used to summarise analytically, and shed light on, wider vistas of change. This paper presents three local images deriving from fieldwork in a small town in mid-Jutland and uses them to tell a bigger story, a narrative about the modernisation of Danish society.     

The IDIP framework for assessing protein function and its application to the prion protein

The quest to determine the function of a protein can represent a profound challenge. Although this task is the mandate of countless research groups, a general framework for how it can be approached is conspicuously lacking. Moreover, even expectations for when the function of a protein can be considered to be ‘known’ are not well defined. In this review, we begin by introducing concepts pertinent to the challenge of protein function assignments. We then propose a framework for inferring a protein's function from four data categories: ‘inheritance’, ‘distribution’, ‘interactions’ and ‘phenotypes’ (IDIP). We document that the functions of proteins emerge at the intersection of inferences drawn from these data categories and emphasise the benefit of considering them in an evolutionary context. We then apply this approach to the cellular prion protein (PrP^C), well known for its central role in prion diseases, whose function continues to be considered elusive by many investigators. We document that available data converge on the conclusion that the function of the prion protein is to control a critical post-translational modification of the neural cell adhesion molecule in the context of epithelial-to-mesenchymal transition and related plasticity programmes. Finally, we argue that this proposed function of PrP^C has already passed the test of time and is concordant with the IDIP framework in a way that other functions considered for this protein fail to achieve. We anticipate that the IDIP framework and the concepts analysed herein will aid the investigation of other proteins whose primary functional assignments have thus far been intractable.     

`Two Laws‘, Ontologies,Histories: Ways of Being Aranda Today

At Hermannsburg, in central Australia, Western Aranda people frequently propose that they live by ‘two laws’, Aranda law and God's law. This is a common phenomenon remarked throughout northern Australia and analysed by a number of anthropologists in the past. This discussion throws new light on the issue by interpreting `two-laws' talk in terms of a culture of encompassment that marks the emergence of historical or ‘ethnic’ identities as Aboriginal people make the transition from an autonomous world to one in which they must engage in the practices of European orders that can come to dominate their lives. The discussion deploys ‘ontology’ and ‘ethnicity’ in order to mark different magnitudes of difference that can shape Aboriginal experience today.     

Learning Courage: Child Labour as Moral Practice in Northeast Brazil

This article explores the moral dimensions of child labour as cultural practice in Northeast Brazil. It reveals a link between children's participation in labour and local constructions of childhood as a period of ontological uncertainty and impending transition. Through detailed ethnographic exegesis, the article reveals the symbolic dimensions surrounding children's engagement in productive endeavours, and shows how the local opposition between ‘work’ and ‘play’ arises out of an encompassing moral process. The article critiques the tendency within protectionist influenced anthropological literature to acknowledge the important contribution that children make towards material survival, while denying that contribution any deeper cultural significance.     

Understanding the ‘epidemic’ of complete tooth loss among older New Zealanders

doi:10.1111/j.1741‐2358.2009.00306.x
Understanding the ‘epidemic’ of complete tooth loss among older New Zealanders Objective: The aim of this study was to obtain a deeper understanding of the social factors driving New Zealand’s historic ‘epidemic of edentulism’ and how they operated. Method: In‐depth, semi‐structured interviews with 31 older New Zealanders were analysed using applied grounded theory. Results: Universal factors present in the data were: (a) the way in which New Zealand society accepted and indeed encouraged edentulism without stigma for those who had a ‘sub‐optimal’ natural dentition; (b) how the predominant patterns of dental care utilisation (symptomatic and extraction‐based) were often strongly influenced by economic and social disadvantage; and (c) the way in which lay and professional worldviews relating to ‘calcium theory’ and dental caries were fundamental in decisions relating to the transition to edentulism. Major influences were rural isolation, the importance of professional authority and how patient‐initiated transitions to edentulism were ultimately facilitated by an accommodating profession. Conclusion: The combined effects of geography, economics, the dental care system and the professional culture of the day, in the context of contemporary (flawed) understandings of oral disease, appear to have been the key drivers. These were supported (in turn) by a widespread acceptance by the profession and society alike of the extraction/denture philosophy in dealing with oral disease.     

A flavour of Alzheimer's

This article describes how today in the United States neurologists diagnose forms of dementia, such as Alzheimer's disease and frontotemporal dementia. Taking as a starting‐point the pervasive context of uncertainty in the diagnosis of neurodegenerative diseases, it examines how uncertainty is not merely an epistemological obstacle to the making of knowledge. On the contrary, the article analyses how uncertainty positively incites the use of clinicians’ ‘feelings’ in diagnostic work. Drawing on observations of clinical consultations and team meetings, it studies how, alongside contemporary instruments of objectification, clinicians use, share, and discuss their ‘feelings’ to ultimately renew knowledge about brain diseases. In documenting the manner in which medical expertise is bound to a concrete experience of the world, this article further explores how experts’ ‘intuition’ can be grasped as a conscious and effortful process, rather than as something ineffable, resisting analysis, and confined to an unconscious background.     

On the role of inter-nucleosomal interactions and intrinsic nucleosome dynamics in chromatin function

Evidence is emerging that many diseases result from defects in gene functions, which, in turn, depend on the local chromatin environment of a gene. However, it still remains not fully clear how chromatin activity code is ‘translated’ to the particular ‘activating’ or ‘repressing’ chromatin structural transition. Commonly, chromatin remodeling in vitro was studied using mononucleosomes as a model. However, recent data suggest that structural reorganization of a single mononucleosome is not equal to remodeling of a nucleosome particle under multinucleosomal content – such as, interaction of nucleosomes via flexible histone termini could significantly alter the mode (and the resulting products) of nucleosome structural transitions. It is becoming evident that a nucleosome array does not constitute just a ‘polymer’ of individual ‘canonical’ nucleosomes due to multiple inter-nucleosomal interactions which affect nucleosome dynamics and structure. It could be hypothesized, that inter-nucleosomal interactions could act in cooperation with nucleosome inherent dynamics to orchestrate DNA-based processes and promote formation and stabilization of highly-dynamic, accessible structure of a nucleosome array. In the proposed paper we would like to discuss the nucleosome dynamics within the chromatin fiber mainly as it pertains to the roles of the structural changes mediated by inter-nucleosomal interactions.     

A relatively cheap photographic film eye-piece grid

A ‘signaller’ (for example, a prey) can avoid detection by a ‘receiver’ (for example, a predator) if its visual signals are difficult to separate from the background. There are two ways by which signallers match the coloration of their background— ‘crypsis’ and ‘masquerade’. We draw attention to the relationships between these two phenomena and how they differ from Batesian mimicry, another adaptation against detection.     

Modelling emotion,perfecting heart: disassembling technologies of affect with an android bodhisattva in Japan

As part of a surge in technologies with so-called ‘artificial emotional intelligence’, robotics engineers and Buddhist monks in Japan have developed an android bodhisattva to deliver teachings at a popular Zen temple. Like many recent robots in Japan, the android is designed to impact visitors’ feelings. For this reason, it can be called a ‘technology of affect’. In order to communicate how new affective technologies are facilitating intimacy in human-machine relations in Japan, we employ the concept of ‘disassembling’. By conceptually disassembling technologies of affect and placing them in performative contexts, we show how technologies of affect also disassemble established associations between artificial agents and the feelings they evoke in popular imaginaries. We argue that identifying these disassembling processes helps demonstrate how emerging AI technologies can engender social change at the level of affect through evocative depictions of machine emotion.     

The Importance of Being Serious: Subjectivity and Adulthood in Kenya

While anthropological scholarship on the life course transitions of young people has aimed to contribute to theories of structure and agency, social reproduction and change, it has done so relatively independently from the anthropological literature on subject formation. This paper explores how subjectivity – how people feel, think, and experience – is implicated in grappling with life course transitions. It addresses how ‘being serious’ is considered a critical adult competency and its achievement delineates a key life transition that young women in western Kenya variously resent and value, resist and seek. The analysis illuminates ways in which people grapple with their own subjectivity as a problem as well as a project, and how such problems and projects of subjectivity are problems and projects of social reproduction. I argue that taking account of such subjective transformations can augment political economy analysis of meanings and modes of life.     

Roadwork: expertise at work building roads in the Maldives

This article engages critically with concepts of ‘skill’, ‘expertise’, and ‘capacity’ as they operate as markers of distinction and domination and shape migratory labour relations among road construction workers from across South Asia in the Maldives archipelago. The article examines roadwork at three levels: the professional biographies leading to ‘flexible specialization’ rather than technical expertise amongst Maldivian managers; the technical expertise and social incorporation of ‘skilled’ Sri Lankan supervisors; and the key material expertise of ‘non-skilled’ Bangladeshi labourers in precarious employment. Whilst discussions of South Asian labour migration have been dominated by caste and class, this article argues that it is important to consider how the cultural production and understanding of concepts such as ‘expertise’, ‘capacity’, and ‘exposure’ at worksites can (also) become distinguishing factors in (hierarchical) migratory labour relations.     

Neutralizing Antibodies Against Allosteric Proteins: Insights From a Bacterial Adhesin

Allosteric proteins transition between ‘inactive’ and ‘active’ states. In general, such proteins assume distinct conformational states at the level of secondary, tertiary and/or quaternary structure. Different conformers of an allosteric protein can be antigenically dissimilar and induce antibodies with a highly distinctive specificities and neutralizing functional effects. Here we summarize studies on various functional types of monoclonal antibodies obtained against different allosteric conformers of the mannose-specific bacterial adhesin FimH – the most common cell attachment protein of Escherichia coli and other enterobacterial pathogens. Included are types of antibodies that activate the FimH function via interaction with ligand-induced binding sites or by wedging between domains as well as antibodies that inhibit FimH through orthosteric, parasteric, or novel dynasteric mechanisms. Understanding the molecular mechanism of antibody action against allosteric proteins provides insights on how to design antibodies with a desired functional effect, including those with neutralizing activity against bacterial and viral cell attachment proteins.     

The influence of genetics on future crop production strategies: from traits to genes, and genes to traits

This paper discusses how a genetical approach to plant physiology can contribute to research underpinning the production of new crop varieties. It highlights the interactions between genetics and plant breeding and how the current advances in genetics and the new science of genomics can contribute to our understanding of the genetical control of key agronomic traits ‐ the process of ‘translating’ traits to identified and mapped genes. Advances in genomics, such as the sequencing of whole genomes and expressed sequence tags, are producing information on genes and gene structures, but without knowing their function. A great deal more biology will be necessary to translate gene structure to function ‐ the process of translating genes to traits. Combining these ‘forward’ and ‘reverse’ genetic approaches will allow us to get comprehensive knowledge of the biology of agronomic traits at the physiological, biochemical and molecular levels, so that the ‘circuitry’ of our crop plants can be elucidated. This will enable plant breeders to manipulate crop phenotype using marker‐assisted breeding or genetic engineering approaches with a precision not previously possible.     

The effect of dusk and dawn on the locomotor activity rhythm of Talitrus saltator (Montagu) (Crustacea: Amphipoda)

Entrainment of the nocturnal, endogenous locomotor activity rhythm of Talitrus saltator (Montagu) by the natural light-dark cycle is non-parametric, the phase of the rhythm shifting only in response to changes in the time of an experimentally simulated ‘dawn’ transition. The difference in response to light at ‘dusk’ and ‘dawn’ illustrates a phase-dependent responsiveness common to endogenous rhythms. Activity begins after complete darkness, with cessation always occurring during the ‘dawn’ transition and never continuing past the onset of total experimental illumination. The point of activity cessation is taken to be the position of a synchronizing cue controlling entrainment. The ‘dawn’ cue appears to be an absolute irradiance level of approximately 1.5 × 10^?4 W/m² (1.5 lux). The implications of such a cue are discussed in relation to field behaviour.     

‘The best borough in the country for cohesion!’: managing place and multiculture in local government

Abstract

In the interface between national and local levels of UK government, narratives of place are made to fit particular tropes of ‘success’ or ‘failure’ at multiculturalism. Thinking through ‘community cohesion’ policy in England between 2001 and 2010, this article shows how (reputations of) relative success at ‘living together with difference’ become a medium through which local government practitioners negotiate the space between national and local priorities, needs and ambitions, by examining how practitioners in English local authorities negotiate narratives of ‘failed multiculturalism’ associated with the places they work and, in doing so, how they re-inscribe or subvert local reputations and their ‘elsewheres’.     

Equivocal locations: being ‘red’ in ‘Red Bologna’

This article addresses a classic ethnographic problem in the study of Italy: how is it that people can subscribe simultaneously to seemingly contradictory ideologies, such as Catholicism and Communism? It does so by describing examples from Italy's ‘showcase city’ of the left, ‘Red Bologna’, in which to be ‘red’ is ubiquitous but each person's ‘red’ is a different thing: being ‘red’ (differently) is the idiom in which real political distinctions are expressed over issues like religion or immigration. In parallel, I discuss the relationship between the ‘field’ as a location and the ‘field’ as a conceptual topic. My account replicates internal ethnographic differences at the analytical level by highlighting the differences between being left‐wing in Bologna and its meaning as a concept in anthropology. Hence the ‘equivocal location’: a field‐site that is productively different, from what an inexperienced ethnographer expected from it, from conceptual discussions in anthropology, and from itself.     

Spectres of Seppo: the afterlives of Finland's nuclear waste experts

This article examines how Finland's nuclear waste repository safety assessment experts summoned memories of Seppo: a deceased colleague whose ‘spectre’ was said to still ‘haunt’ their workplace. First, it tracks how Seppo appeared in predecessor parables: cautionary tales told about his death, which conveyed value judgements about how experts ought to act, engage, and aspire. Second, it explores how Seppo's long-time ‘right-hand man’ Gustav still felt haunted by his colleague's affective intensities, scientific vision, and sharp tongue. This led Gustav to prod his workmates to reconsider how they modelled Finland's ecosystems many millennia into the future. Studying this ethnographically revealed how traces of Seppo's past life infused living experts with emotions, opened them to alternative futures, and spurred them to rethink their professional values. This article concludes by introducing expert afterlives as a temporal, epistemic, and affective nexus that can shape how technocratic projects are organized and how expert knowledge is made.     

The Social Life of Death on Delhi's Streets: Unclaimed Souls,Pollutive Bodies,Dead Kin and the Kinless Dead

ABSTRACT

How does the status of ‘street children’ in life inflect the narrative representation of their deaths? Street-dwelling children's interactions with death in North India reveal much about how their identities are produced in public domains. In this paper, I examine several instances of ‘homeless child’ death to illuminate the place of such subjects in society and urban space, and to interrogate the degree to which they can be rendered ‘recognizable’ or ‘grievable’, in Butler's (2010) terminology. In particular, I explore the presence or absence of kin in the ways that child death is narrated. I also explore the related question of how living ‘vagabond (aawara) children’ situate their status in narratives of death and loss. I conclude with discussions of how children negotiate their orientations towards death through ghost narratives, and of the space-, economy- and age-bound assignment of pollutive tasks once reserved for low castes to street-dwelling children.     

Forensic culture as epistemic culture: The sociology of forensic science

This paper explores whether we can interpret the notion of ‘forensic culture’ as something akin to what Knorr-Cetina called an ‘epistemic culture’. Can we speak of a ‘forensic culture’, and, if so, how is it similar to, or different from, other epistemic cultures that exist in what is conventionally called ‘science’? This question has important policy implications given the National Academy Science’s (NAS) recent identification of ‘culture’ as one of the problems at the root of what it identified as ‘serious deficiencies’ in U.S. forensic science and ‘scientific culture’ as an antidote to those problems. Finding the NAS’s characterisation of ‘scientific culture’ overly general and naïve, this paper offers a preliminary exploration of what might be called a ‘forensic culture’. Specifically, the paper explores the way in which few of the empirical findings accumulated by sociologists of science about research science seem to apply to forensic science. Instead, forensic science seems to have developed a distinct culture for which a sociological analysis will require new explanatory tools. Faithful sociological analysis of ‘forensic culture’ will be a necessary prerequisite for the kind of culture change prescribed by external reformist bodies like the NAS.