新型骨水泥椎弓根螺钉在治疗腰椎滑脱合并骨质疏松症的应用研究

目的:探讨评估聚甲基丙烯酸甲酯(polymethvlmethacnrlat, PMMA)增强的具有"渐变孔"结构的侧开孔中空椎弓根螺钉(Fenestrated pedicle screw, FPS)治疗腰椎滑脱症的安全性及疗效。方法:回顾性分析2013年1月～2017年12月收治32例合并有骨质疏松症的腰椎滑脱患者,均应用具有"渐变孔"结构的FPS融合手术治疗,记录手术时长、术中出血量,住院时长;测量椎间隙高度、椎体楔形变指数、滑脱距离、滑脱角、骨盆指数、腰椎前凸角;随访评估Oswestry功能障碍指数问卷表(Oswestry Disability Index Questionnaire, ODI)评分和视觉模拟评分法(Visual Analogue Score, VAS)评分,比较分析术前、术后及末次随访时的差异;结果:术中X线及术后三维CT检查发现3枚渗漏的骨水泥螺钉(2.2%),均为Yeom C型,术后无不适。随访7～61个月(平均34.9个月),滑脱复位良好,后凸畸形和矢状位失衡矫正良好,ODI评分和VAS评分均较术前有显著改善(p0.05)。随访期间,全部病例滑脱无复发,无椎弓根螺钉松动、断裂,无椎间隙塌陷,根据SUK标准融合成功率100%。结论:新型骨水泥螺钉能够提供良好的固定稳定性,并且能够避免骨水泥渗漏发生以及螺钉松动脱出,为骨质疏松脊柱手术提供一种新的选择。     

椎体静脉稀疏区注入骨水泥对PVP术中骨水泥渗漏的影响

目的:探讨椎体静脉稀疏区注入骨水泥对骨质疏松椎体压缩性骨折患者行经皮穿刺椎体成形术(percutaneous vertebroplasty,PVP)术中骨水泥渗漏的影响。方法:选择西安交通大学第二附属医院2014年1月至2018年6月收治的61例骨质疏松椎体压缩性骨折患者,根据骨水泥注入区域的不同,将所有患者分为A组(30例)及B组(31例),A组骨水泥注入区域为椎体静脉密集区(椎体中1/3平面处),B组骨水泥注入区域为椎体静脉稀疏区(椎体上1/3及下1/3平面处),对比两组的骨水泥渗漏率,术前、术后6个月时的视觉模拟评分(Visual analogue scale,VAS),治疗中的骨水泥用量、椎体高度恢复率及cobb角恢复度数。结果:B组的骨水泥渗漏率及骨水泥用量均明显低于A组(P0.05)。两组的VAS评分、椎体高度恢复率、cobb角恢复情况对比差异无统计学意义(P0.05)。结论:与椎体静脉密集区相比,在椎体静脉稀疏区注入骨水泥可显著降低骨质疏松椎体压缩性骨折患者PVP术中骨水泥渗漏率,椎体静脉稀疏区可作为PVP术中骨水泥注射的一个相对安全区域。     

经皮椎体后凸成形术对绝经后女性椎体骨折的疗效分析

目的：分析经皮椎体后凸成形术对绝经后女性椎体骨折的疗效。方法：选取68例绝经后女性椎体骨折患者并随机分为研究组和对照组,每组各34例。研究组采用经皮椎体后凸成形术（PKP）治疗,对照组采用经皮椎体成形术PVP）治疗。分剐在术前、术后1d以及术后1年对患者进行疼痛视觉类比评分WAS）,观察随访期间Cobb角的矫正程度和骨水泥渗漏情况以及相邻椎体的骨折发生率。结果：两组患者在术后各时间点VAS评分和Cobb角的矫正程度均有明显的改善（P〈0．05）,其中研究组术后Cobb角的矫正程度要明显优于对照组（P〈0．05）,同时研究组患者术后骨水泥渗漏的发生率低于对照组（P〈0．05）,在随访期内,对照组相邻椎体骨折的发生率高于研究组（P〈0．05）。结论：PVP和PKP均能显著缓解OVCF疼痛,但是PKP比PVP更有利于矫正脊柱后凸的畸形,同时降低骨水泥渗漏和相邻椎体骨折的发生率。     

经皮椎体成形术与保守疗法治疗胸腰椎骨质疏松性骨折的比较研究

目的:研究经皮椎体成形术与保守疗法治疗胸腰椎骨质疏松性骨折的临床疗效。方法:选取2013年7月到2014年7月我院收治的胸腰椎骨质疏松性骨折患者110例,按照随机数字表法将患者分为研究组和对照组,每组55例。对照组给予保守疗法治疗,研究组给予经皮椎体成形术治疗,比较两组临床疗效,应用视觉模拟评分法(VAS)评价治疗前后的疼痛情况,并分析Cobb角度和并发症。结果:研究组总有效率90.9%显著高于对照组的76.4%(P0.05);治疗后研究组VAS评分显著低于对照组(P0.05);两组并发症发生率比较无统计学意义(P0.05)。结论:经皮椎体成形术治疗胸腰椎骨质疏松性骨折具有较好的临床疗效,能有效改善腰椎部疼痛症状。     

PLIF与TLIF手术治疗老年单节段腰椎退变性疾病的临床疗效对比

目的:探讨改良后路腰椎体间融合术(PLIF)与改良经椎间孔入路腰椎体间融合术(TLIF)手术治疗老年单节段腰椎退变性疾病的临床疗效。方法:收集2009年1月-2015年1月期间我院收治的经确诊为老年单节段腰椎退变性疾病的80例患者,按照随机数字表法分为观察组和对照组,各40例;观察组患者采用TLIF手术,对照组患者采用PLIF手术;比较两组患者手术前后腰背部疼痛程度(VAS评分)与活动功能(ODI评分),临床指标及并发症发生率。结果:观察组患者手术时间、术中出血量及术后引流量均明显短于或少于对照组患者(P0.05);两组患者手术前腰背部VAS评分与ODI评分比较差异无统计学意义(P0.05),手术后6个月,两组患者腰背部VAS评分与ODI评分均明显低于手术前(P0.05),而组间比较差异无统计学差异(P0.05);观察组术后并发症总发生率为5.00%(2/40),显著低于对照组的22.50%(9/40),差异有统计学差异(P0.05)。结论:PLIF与TLIF手术治疗老年单节段腰椎退变性疾病患者在改善腰背部疼痛程度与腰椎活动功能中的疗效相当,但TLIF手术有助于显著缩短手术时间,降低术中出血量与术后引流量,降低术后并发症发生风险,值得临床推广应用。     

Material changes in osteoporotic human cancellous bone following infiltration with acrylic bone cement for a vertebral cement augmentation

Bone cement infiltration can be effective at mechanically augmenting osteoporotic vertebrae. While most published literature describes the gain in mechanical strength of augmented vertebrae, we report the first measurements of viscoelastic material changes of cancellous bone due to cement infiltration. We infiltrated cancellous core specimen harvested from osteoporotic cadaveric spines with acrylic bone cement. Bone specimen before and after cement infiltration were subjected to identical quasi-static and relaxation loading in confined and free compression. Testing data were fitted to a linear viscoelastic model of compressible material and the model parameters for cement, native cancellous bone, and cancellous bone infiltrated (composite) with cement were identified. The fitting demonstrated that the linear viscoelastic model presented in this paper accurately describes the mechanical behaviour of cement and bone, before and after infiltration. Although the composite specimen did not completely adopt the properties of bulk bone cement, the stiffening of cancellous bone due to cement infiltration is considerable. The composite was, for example, 8.5 times stiffer than native bone. The local stiffening of cancellous bone in patients may alter the load transfer of the augmented motion segment and may be the cause of subsequent fractures in the vertebrae adjacent to the ones infiltrated with cement. The material model and parameters in this paper, together with an adequate finite-element model, can be helpful to investigate the load shift, the mechanism for subsequent fractures, and filling patterns for ideal cement infiltration.     

Mineral nutrition in carnation tissue cultures under different ventilation conditions

Growth and propagation rates, hyperhydricity percentages, macronutrientabsorption and pH evolution were evaluated in Dianthuscaryophyllus CV Nelken cultured in vitro under different ventilationconditions. Culture in well ventilated conditions (HVC) i.e. low relativehumidity, generated lower percentages of hyperhydric explants, with highermicropropagation coefficients and dry weight increments, than in less ventilatedcultures (LVC). Macronutrient absorption was similar in both types of cultures,except for ammonium, nitrate, chloride and phosphate. In LVC, after 15 days ofculture, carnation explants absorbed more nitrate than ammonium and chlorideuptake was 5 times greater than in HVC. Phosphate uptake was more pronounced inLVC after 15 days of culture, reaching similar values in both types of culturevessels at the end of the experiment, and led to growth limiting conditions formore prolonged cultures. Medium pH decreased to acid values after 15 days ofculture and even more at the end of the experiment; however, these acidconditions seem not be an obstacle for nutrient absorption.     

O型臂引导下经皮椎间孔镜治疗腰椎间盘突出症

目的:总结O型臂引导下经皮椎间孔镜治疗腰椎间盘突出症术后疗效。方法:回顾性分析77例采用侧入路椎间孔镜技术治疗腰椎间盘突出症患者的临床资料,采用视觉模拟评分法(visual analogue score,VAS)及Oswestry功能障碍指数(Oswestry disability index,ODI)评估术后疼痛、功能改善等。结果:患者术前VAS7.5±1.2,ODI(%)62.7±16.0,术后6个月VAS1.6±1.9,ODI(%)32.1±24.3,治疗效果明显,且无严重并发症,少数短期并发症可恢复。结论:O型臂引导下经皮椎间孔镜是治疗腰椎间盘突出症安全、有效的微创手术方式。     

Repositioning Suture of the Erector Spinae Muscle for Lumbar Spine Surgery via the Posterior Approach: A Prospective Randomized Study

We prospectively studied the effectiveness of the repositioning suture of the erector spinae muscle for lumbar spine surgery using the posterior approach. 393 patients undergoing lumbar spine surgery were randomized to receive the repositioning or conventional suture of the erector spinae muscle. Time to stitch removal and drainage volume was recorded at 24 and 48 h after operation. Hemoglobin loss rate was determined at 48 h post operation and the rate of malunion (redness, swelling and effusion at stitch removal and would disruption after stitch removal) was recorded. Low back pain was evaluated using the visual analog scale (VAS) preoperatively and 6 and 12 months after operation. Time to stitch removal was comparable in lumbar spine surgery patients receiving the repositioning or conventional suture of the erector spinae muscle (P > 0.05). Compared with the conventional suture, the repositioning suture was associated with significantly reduced drainage volume both at 24 (P < 0.01) and 48 h after operation (P < 0.05). Hemoglobin loss rate at 48 h post operation was also markedly lower in lumbar spine surgery patients receiving the repositioning suture than in those receiving the conventional suture (P < 0.01 or 0.05). Furthermore, the malunion rate in lumbar spine surgery patients using the repositioning suture was markedly lower than that in the conventional group (P < 0.05 or 0.001). There was no difference in preoperative VAS scores in both the groups (P > 0.05). Compared with the conventional suture, the repositioning suture was associated with significantly reduced VAS scores both at 24 and 48 h after operation (P < 0.01 in both). The repositioning suture of the erector spinae muscle is superior to the conventional suture in posterior lumbar spine surgery with marked lessened pain and reduced drainage volume.     

不同术式经皮椎间孔镜治疗腰椎间盘突出症的疗效分析

目的:探讨不同术式经皮椎间孔镜治疗腰椎间盘突出症的疗效。方法:选取我院2013年9月~2015年7月我院收治的采用经皮椎间孔镜治疗的腰椎间盘突出症患者159例,根据不同手术方式进行分组,其中采用YESS手术的36例患者作为YESS组,采用TESSYS手术的76例患者作为TESSYS组,采用BEIS手术(即改良的TESSYS手术)的47例患者作为BEIS组。于术前、术后1天、3个月、6个月、12个月对所有患者进行视觉疼痛模拟评分(VAS)和改良的MacNab疗效评定。结果:三组的手术时间、术中出血量、住院时间比较差异有统计学意义(P0.05),BEIS组和TESSYS组的手术时间、术中出血量高于YESS组,且BEIS组手术时间、术中出血量高于TESSYS组,BEIS组的住院时间高于YESS组和TESSYS组,差异均有统计学意义(P0.05)。三组患者术后各时期VAS评分均较术前降低(P0.05),但三组间术前、术后不同时期VAS评分整体比较均无统计学差异(P0.05)。三组优良率整体比较,差异无统计学意义(P0.05)。结论:不同术式经皮椎间孔镜治疗腰椎间盘突出症的疗效相当,可以有效减轻术后患者的疼痛,但是三种术式的手术时间、术中出血量、住院时间有所差异,临床上针对不同类型的腰椎间盘突出症应采用不同术式,以获得更确切的疗效。     

腰椎间盘突出症阶梯式手术治疗方案的临床疗效和患者心理状况调查

目的:探讨阶梯式手术治疗方案对腰椎间盘突出的临床疗效和患者对临床疗效的心理接受情况。方法:回顾性分析2014年至2016年本院骨科确诊为腰椎间盘突出症的50例患者,经椎间孔镜下行髓核摘除微创手术(Percutaneous transforaminal endoscopic discectomy,PTED),术后1天和3个月采用视觉疼痛模拟评分(VAS)和改良Mac Nab疗效评定、术后3个月采用Oswestry功能障碍指数(ODI)评价手术效果,以及相应调查时间点患者对手术效果心理接受程度调查;对于7例微创手术疗效不佳患者进一步采用传统的开窗髓核摘除术(Fenestration discectomy,FD),采用同样方法评价手术效果和调查患者心理接受情况。结果:50例微创术后1天及术后3个月的VAS评分和ODI指数均显著低于术前,差异具有显著性(P均0.05);改良Mac Nab疗效评定:术后1天优良率为84%,术后3个月为86%;患者对术后疗效心理满意度调查:术后1天,满意并接受为84%,不满意但接受为16%,不满意难接受为0;术后3个月,满意并接受为86%,不满意但接受为14%,不满意难接受为0。对于微创术后效果欠佳7例患者行FD手术,术后1天及3个月的VAS评分和ODI指数均显著低于术前,差异具有显著性(P均0.05);改良Mac Nab疗效评定:术后1天优良率为71%,术后3个月为100%;患者对开窗术后疗效心理满意度调查:术后1天,满意并接受为71%,不满意但接受为0,不满意难接受为29%;术后3个月,满意并接受为100%,不满意但接受为0,不满意难接受为0。结论:腰椎间盘突出症阶梯式手术治疗方案临床效果和患者心理接受情况均值得临床推荐。     

经皮椎间孔镜治疗腰椎间盘突出症临床疗效观察

目的:评估经皮椎间孔镜技术(percutaneous transforaminal endoscopic discectomy,PTED)治疗腰椎间盘突出症的临床疗效。方法:回顾性分析2009~2013年我院收治的明确诊断为腰椎间盘突出症且接受PTED治疗的194例患者的临床和随访资料,评价其Mac Nab疗效,比较手术前后患者的VAS疼痛评分、Lehmann腰椎功能评分及SF-36生存质量评分。结果:所有患者均至少随访至术后12月,患者术后当天及术后3月、12月的VAS评分、Lehmann腰椎功能评分、SF-36生存质量评分均较术前明显改善,差异均具有统计学意义(P0.05)。术后3月、12月,患者Macnab疗效的优良率分别为90.7%、92.3%。结论:采用PTED治疗腰椎间盘突出症的临床疗效较好,患者的疼痛明显缓解,腰椎功能和生活质量均明显改善,且安全方便。     

网袋强化椎体成形术在骨质疏松椎体骨折治疗中的经验教训

摘要 目的：探讨和总结使用网袋强化椎体成形术在骨质疏松椎体骨折围手术期的注意事项及相关对策。方法：回顾性分析2017年6月到2020年6月3年时间内,使用网袋强化椎体成形术治疗骨质疏松性椎体骨折患者共计112例。统计和比较患者在围手术期的各项指标,分析穿刺失败的原因及相关危险因素。结果：112例患者共涉及138个椎体。其中一期穿刺失败率（骨水泥分布不佳）为47个,占34.0%。骨水泥注入3 mL以下者为19个,占13.8%。骨水泥渗漏为36个,占26.1%。所有患者在术后3天及3月复查, VAS评分和ODI评分较前均有显著改善(P<0.05)。所有患者均未出现严重并发症(P>0.05)。结论：网袋强化椎体成形术在骨质疏松性椎体骨折的治疗中是一种理想的治疗方式,但在具体过程中仍有相关的经验和教训需要整理和总结。     

经皮椎体成形术治疗椎体血管瘤疗效观察

目的:评估使用经皮椎体成形术(Percutaneous vertebroplast PVP)治疗椎体血管瘤的临床疗效。方法:回顾性分析2008~2015年诊断为椎体血管瘤并在我院进行PVP手术的46例患者,至少6个月术后随访,获取相关的临床数据和资料。对患者在术后疼痛等症状改善,肿瘤复发,Macnab疗效和治疗安全性等方面进行分析。结果:所有患者均在术后有了明显的疼痛改善(P0.05),并在6个月内随着时间的推移疼痛评分逐步下降。有2例患者出现术后肿瘤复发,但无明显症状,未给予特殊处理。余未出现明显并发症。患者的术后SF-36生存质量评分均较术前有较大提高(P0.05)。在患者术后6月时,对其Macnab疗效进行分析,其优良率为93.5%。结论:经皮椎体成形术治疗椎体血管瘤可以有效的改善疼痛症状,且相对安全,并能实现微创治疗。     

单侧与双侧PVP治疗骨质疏松性椎体压缩骨折临床疗效比较及骨水泥渗漏的危险因素分析

摘要 目的：比较单侧与双侧经皮椎体成形术（PVP）治疗骨质疏松性椎体压缩骨折（OVCF）的临床疗效,并分析骨水泥渗漏的危险因素。方法：回顾性分析2019年5月~2020年12月期间本院收治的205例OVCF患者的临床资料,根据入路方式的不同分为单侧组和双侧组,例数分别为104例和101例。对比两组围术期指标、视觉模拟评分（VAS）、Oswestry功能障碍指数（ODI）、Cobb''s角和椎体前缘高度,记录两组骨水泥渗漏及其他并发症发生情况,采用单因素及多因素Logistic回归分析骨水泥渗漏的影响因素。结果：与双侧组相比,单侧组手术时间缩短,骨水泥注入量、术中透视次数减少（P<0.05）。两组术前、术后3个月、末次随访时VAS、ODI评分均呈下降趋势（P<0.05）。与术前相比,两组术后3个月及末次随访时的椎体前缘高度均升高,Cobb''s角均缩小（P<0.05）。两组并发症发生率组间对比无统计学差异（P>0.05）。PVP患者骨水泥渗漏与骨水泥黏度、皮质断裂、骨折严重程度、骨折位置、年龄、CT值、骨水泥注入量有关（P<0.05）。骨水泥渗漏的危险因素主要有骨水泥注入量>6 mL、骨折严重程度为重度、CT值>63HU、骨水泥黏度为低、皮质断裂（P<0.05）。结论：单侧与双侧PVP治疗OVCF效果相当。其中单侧可减少骨水泥注入量,缩短手术时间,减轻术后疼痛,促进术后功能恢复。而PVP手术最常见的并发症为骨水泥渗漏,受到骨折严重程度、皮质断裂、骨水泥黏度等因素的影响。     

Proxomed Tergumed用于椎间孔镜术后早期康复的临床效果分析

目的:探讨Proxomed Tergumed系统用于腰椎间盘突出症椎间孔镜术后早期康复的治疗效果。方法:按照纳入和排除标准,选择2016年6月至2017年6月在我科明确诊断为腰椎间盘突出症并进行腰椎间孔镜手术的63例患者进行回顾性分析。按照是否进行系统的Proxomed Tergumed脊柱功能训练,将其分为功能训练组实验组(28例)与对照组(35例)。比较两组患者在术前、术后1周、术后3月及术后6月的疼痛(VAS)、功能评分(ODI)、相关肌肉力量及术后并发症的发生情况。结果:两组患者术后的VAS评分及ODI评分均较术前明显降低(P0.05)。术后1周时,两组VAS评分及ODI评分比较差异无统计学意义(P0.05)。术后3月及6月,实验组VAS评分和ODI评分均显著低于对照组(P0.05)。术后6个月,实验组肌力恢复显著优于对照组(P0.05)。术后6月,实验组各肌肉群力量与术前相比均无显著差异(P0.05),而对照组肌肉群力量仍较术前显著降低(P0.05)。结论:Proxomed Tergumed系统在腰椎间盘突出症椎间孔镜术后的康复中可以有效的降低患者的术后疼痛,改善患者的腰椎功能,相对于传统的术后康复训练而言有其明显的优势,且并无显著的安全性差异。     

Will cardiac surgery improve my quality of life?

Background. The intention of this study is to analyse the correlation between a visual analogue scale (VAS) and the most common preoperative comorbidity and cardiac variables in patients undergoing elective cardiac surgery. This VAS is simple, easy to register and can be used as a global measurement of quality of life (QOL). Methods. Preoperative assessment of QOL in 1351 patients, 979 men and 372 women, with a mean age of 64.5±10.5 (18-88), undergoing elective cardiac surgery between January 2003 and December 2005. QOL was measured by the EuroQol questionnaire. Results. The mean VAS was 58.7±20.9, range 3 to 100. Univariate analysis showed a difference for sex (p=0.000), and NYHA (p=0.009) between patients with an isolated CABG and those with a combined revascularisation (p=0.05). Stepwise logistic regression analysis identified female gender (p=0.00), NYHA (p=0.00) and valve disease (p=0.03) as independent variables for a low QOL. The correlation between NYHA and QOL was low (r=-0.09, p=0.003). Conclusion. The clinical consequence is that using this simple VAS we can identify patients with a good QOL. If these patients present for high-risk surgery, with a better quality of life as primary indication, more extended counselling regarding their QOL is recommended. (Neth Heart J 2007; 15:51-4.)     

全膝关节置换术对膝关节骨关节炎患者关节功能的影响

目的:探讨全膝关节置换术(TKA)对膝关节骨关节炎患者术后关节功能的影响。方法:回顾性分析2013年8月-2015年8月我院收治的76例膝关节骨关节炎患者的临床资料,所有患者均采用全膝关节置换术治疗。观察并比较患者手术前后膝关节HSS评分、膝关节疼痛目测类比评分(VAS)、膝关节屈曲活动度(ROM)的变化情况。结果:患者术后膝关节HSS评分、膝关节疼痛评分VAS及ROM均明显高于术前,差异具有统计学意义(P0.05);术前HSS评分、膝关节疼痛VAS评分、膝关节ROM、胫骨平台后倾角(PSA)以及股骨前髁偏距(ACO)与术后膝关节HSS评分呈正相关关系,而内翻畸形角度与术后膝关节HSS评分呈负相关关系,差异具有统计学意义(P0.05)。结论:全髋关节置换术能够改善骨关节炎患者的膝关节功能,并且术前膝关节HSS评分、膝关节疼痛VAS评分及PSA与术后患者髋关节功能恢复程度有关。     

Functional implications of variation in lumbar vertebral count among hominins

As early as the 1970s, Robinson defined lumbar vertebrae according to their zygapophyseal orientation. He identified six lumbar elements in fossil Sts 14 Australopithecus africanus, one more than is commonly present in modern humans. It is now generally inferred that the modal number of lumbar vertebrae for australopiths and early Homo was six, from which the mode of five in later Homo is derived. The two central questions this study investigates are (1) to what extent do differences in human lumbar vertebral count affect lordotic shape and lumbar function, and (2) what does lumbar number variation imply about lumbar spine function in early hominins? To address these questions, I first outline a biomechanical model of lumbar number effect on lordotic function. I then identify relevant morphological differences in the human modal and extra-modal variants, which I use to test the model. These tests permit evaluation of the human L6 variant as a model for reconstructing early hominin modal number and spine function. Application of the biomechanical model in reconstructing australopith/early Homo lumbar spines highlights shared principles of Euler column strength and sagittal spine flexibility among early and modern hominins. Within modern humans, the extra-modal L6 variant has an extended series of three cranially positioned kyphotic vertebrae and strongly oblique zygapophyseal facets at the last lumbar level. Although they share the same radius and length of lumbar curvature, the L6 variant differs functionally from the L5 mode in its expanded range of sagittal flexion/extension and enhanced resistance to shear. Given the modal number of six lumbar vertebrae in australopiths and early Homo, lumbar spine mobility and strength would have been key properties of vertebral function in early bipeds whose upper and lower body segments were coupled by close approximation of the thorax and iliac crests.     

腰丛-坐骨神经阻滞与腰硬联合麻醉用于老年患者下肢手术中的效果比较

目的:分析和比较两种不同麻醉方式(腰丛-坐骨神经阻滞麻醉与腰硬联合麻醉)对老年患者下肢骨折手术中的效果。方法:以我院收治的下肢骨折拟行手术治疗的老年患者158例作为研究对象,将其随机分为腰硬联合麻醉组(CSEA)和腰丛-坐骨神经阻滞组(LPSB),每组各79例。CSEA组采用腰硬联合麻醉,LPSB组采用腰丛-坐骨神经阻滞,比较两组患者感觉阻滞起效时间、运动阻滞起效时间、运动恢复时间、维持时间、疼痛感觉评分和并发症的发生状况。结果:CSEA组和LPSB分别有1例和3例患者因局部麻醉失效而需全身麻醉;LPSB组的感觉阻滞起效时间、运动阻滞起效时间、运动恢复时间均显著晚于CSEA组,但其维持时间显著长于CSEA组,患者疼痛感觉评分低于CSEA组(P0.05)。结论:与腰硬联合麻醉相比,腰丛-坐骨神经阻滞能为老年下肢骨折手术患者提供有效的单侧麻醉,且安全性高,可作为下肢骨科手术患者的首选麻醉方案。