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1.
DNA samples from Falasha Jews and Ethiopians were studied with the Y-chromosome-specific DNA probe p49a to screen for TaqI restriction polymorphisms and haplotypes. Two haplotypes (V and XI) are the most widespread in Falashas and Ethiopians, representing about 70% of the total number of haplotypes in Ethiopia. Because the Jewish haplotypes VII and VIII are not represented in the Falasha population, we conclude that the Falasha people descended from ancient inhabitants of Ethiopia who converted to Judaism. 相似文献
2.
Chen-Shtoyerman R Josefsberg Ben-Yehoshua S Nissani R Rosensaft J Appelman Z 《Cytogenetic and genome research》2012,136(3):171-174
We describe 7 cases of abnormal karyotypes involving chromosomes Y and 15 in Ethiopian Beta Israel patients: 46,XX, der(15)t(Y;15)(q12;p12) and 46,XY,der(15)t(Y;15)(q12;p12). Six cases were incidentally found in amniocentesis performed for various indications; the indication for karyotyping in 1 case was recurrent abortions. To the best of our knowledge, this is the first report of this translocation in a specific ethnic group. We conclude that the derivative chromosome 15 with chromosome Y is probably a normal variant in Ethiopian Beta Israel occurring at an estimated frequency of 4/74 (5.4%). The prenatal diagnosis of this translocation in this population probably does not require further parental testing. 相似文献
3.
Clutch size of passerines at mid-latitudes: the possible effect of competition with migrants 总被引:1,自引:0,他引:1
YORAM YOM-TOV 《Ibis》1994,136(2):161-165
The clutch sizes of the passerines of Israel and the Cape Province, South Africa, which lie at similar latitudinal range, were compared. Mean clutch sizes in Israel and the Cape Province are 4.09 and 2.87, respectively. Mean clutch size of Israeli migrants is larger than that of residents (4.45 and 3.93, respectively), but no such difference exists in the Cape Province.
It is suggested that the larger clutch size in Israel is a result of two factors: (1) the higher proportion of wintering birds in Israel in comparison with the Cape Province and the presence of many transients there which may compete with resident birds and cause high winter mortality among them and (2) a higher proportion of migrants in the Israel avifauna, which suffer heavy losses during their trans-Saharan migration in comparison with Cape Province migrants, which travel shorter routes. The resulting reduced competition for food during the breeding season in Israel enables passerines there to lay larger clutches as predicted by Ashmole (1963) and Ricklefs (1980). 相似文献
It is suggested that the larger clutch size in Israel is a result of two factors: (1) the higher proportion of wintering birds in Israel in comparison with the Cape Province and the presence of many transients there which may compete with resident birds and cause high winter mortality among them and (2) a higher proportion of migrants in the Israel avifauna, which suffer heavy losses during their trans-Saharan migration in comparison with Cape Province migrants, which travel shorter routes. The resulting reduced competition for food during the breeding season in Israel enables passerines there to lay larger clutches as predicted by Ashmole (1963) and Ricklefs (1980). 相似文献
4.
Allen MP Xu M Linseman DA Pawlowski JE Bokoch GM Heidenreich KA Wierman ME 《The Journal of biological chemistry》2002,277(41):38133-38140
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Shmueli, M., Arad, Z., Izhaki, I. & Crivelli, A. 2000. The energetic demand of the Great White Pelican during migration in Israel and its implication to the conflict between fish industry and pelicans. Ostrich 71 (1 & 2): 1. The Great White Pelican Pelecanus onocrotalus is a migrating bird, which is an endangered species. The majority of the western Palaearctic populations stopover in Israel during their autumn migration (71 421 ± 127 individuals per year). Although most of these birds are transient over Israel, an increasing number of individuals (1 142 ± 882, between 1990–1994) stay and winter in the northern part of Israel. The natural feeding sites for pelicans diminished during recent decades due to human activities, and the aquaculture sites of intensive fishery became their favourite feeding places either during migration or during winter. The fish industry reports huge damages to fish yield. This study tried to assess ecophysiological needs of the White pelicans during migration and wintering in Israel, and to evaluate the necessity for pelicans to feed in Israel on their route to east-central Africa. The study combines laboratory measurements of energy consumption of captive pelicans, and field observations of migrant and wintering pelicans, and satellite tracking of migrating pelicans. The mean mass-specific metabolic rate (BMR) of the pelican was 236 kJ/(kg*day), without significant differences between sexes or diets (fish or chicks) and seasons: digestible energy intake (DEI) was 490–730 kJ/(kg*day) also without significant differences between sexes and diets. Wet food consumption (WFC) was greater on the fish diet (1.120 kg/day per bird) than on the chick diet (0.970 kg/day). Digestive efficiency was higher on the fish than on the chick diet (86% and 77%, respectively). Fat deposition in dead migrant pelicans during autumn, was 290 g (3.4% + 2.6% of body mass, n = 81). Fat deposition in wintering pelicans was significantly higher (5.4% ± 3.4% of body mass, n = 21). From these data, the average flight range of transient pelicans was estimated as 1 120 km without refueling. Although satellite records gave us information on the northward migration routes of pelicans from Israel, we need further information about the precise area of the pelicans in Africa. Nevertheless it is concluded that pelicans need to feed during their stopover in Israel, or at some unknown feeding sites along their southward migratory route, to complete their journey to their wintering grounds in east-central Africa. The results of this research should contribute to the establishment of new management policies, to the solution of conflict with the fish industry and to the conservation of pelicans in Israel. 相似文献
6.
Novel Mechanism for Gonadotropin-Releasing Hormone Neuronal Migration Involving Gas6/Ark Signaling to p38 Mitogen-Activated Protein Kinase 总被引:10,自引:0,他引:10
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Melissa P. Allen Daniel A. Linseman Hiroshi Udo Mei Xu Jerome B. Schaack Brian Varnum Eric R. Kandel Kim A. Heidenreich Margaret E. Wierman 《Molecular and cellular biology》2002,22(2):599-613
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The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis
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The chromosomal passenger proteins aurora-B, survivin, and inner centromere protein (INCENP) have been implicated in coordinating chromosome segregation with cell division. This work describes the interplay between aurora, survivin, and INCENP orthologs in the fission yeast Schizosaccharomyces pombe and defines their roles in regulating chromosome segregation and cytokinesis. We describe the cloning and characterization of the aurora-related kinase gene ark1(+), demonstrating that it is an essential gene required for sister chromatid segregation. Cells lacking Ark1p exhibit the cut phenotype, DNA fragmentation, and other defects in chromosome segregation. Overexpression of a kinase-defective version of Ark1, Ark1-K147R, inhibits cytokinesis, with cells exhibiting an elongated, multiseptate phenotype. Ark1p interacts physically and/or genetically with the survivin and INCENP orthologs Bir1p and Pic1p. We identified Pic1p in a two-hybrid screen for Ark1-K147R interacting partners and went on to map domains in both proteins that mediate their binding. Pic1p residues 925-972 are necessary and sufficient for Ark1p binding, which occurs through the kinase domain. As with Ark1-K147R, overexpression of Ark1p-binding fragments of Pic1p leads to multiseptate phenotypes. We also provide evidence that the dominant-negative effect of Ark1-K147R requires Pic1p binding, indicating that the formation of Ark1p-Pic1p complexes is required for the execution of cytokinesis. 相似文献
9.
Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast
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Ark1p (actin regulating kinase 1) was identified as a yeast protein that binds to Sla2p, an evolutionarily conserved cortical actin cytoskeleton protein. Ark1p and a second yeast protein, Prk1p, contain NH2-terminal kinase domains that are 70% identical. Together with six other putative kinases from a number of organisms, these proteins define a new protein kinase family that we have named the Ark family. Lack of both Ark1p and Prk1p resulted in the formation of large cytoplasmic actin clumps and severe defects in cell growth. These defects were rescued by wild-type, but not by kinase-dead versions of the proteins. Elevated levels of either Ark1p or Prk1p caused a number of actin and cell morphological defects that were not observed when the kinase-dead versions were overexpressed instead. Ark1p and Prk1p were shown to localize to actin cortical patches, making these two kinases the first signaling proteins demonstrated to be patch components. These results suggest that Ark1p and Prk1p may be downstream effectors of signaling pathways that control actin patch organization and function. Furthermore, results of double-mutant analyses suggest that Ark1p and Prk1p function in overlapping but distinct pathways that regulate the cortical actin cytoskeleton. 相似文献
10.
Dallas JF Cruickshank RH Linton YM Nolan DV Patakakis M Braverman Y Capela R Capela M Pena I Meiswinkel R Ortega MD Baylis M Mellor PS Mordue Luntz AJ 《Medical and veterinary entomology》2003,17(4):379-387
The biting midge Culicoides imicola Kieffer (Diptera: Ceratopogonidae) is the most important Old World vector of African horse sickness (AHS) and bluetongue (BT). Recent increases of BT incidence in the Mediterranean basin are attributed to its increased abundance and distribution. The phylogenetic status and genetic structure of C. imicola in this region are unknown, despite the importance of these aspects for BT epidemiology in the North American BT vector. In this study, analyses of partial mitochondrial cytochrome oxidase subunit I gene (COI) sequences were used to infer phylogenetic relationships among 50 C. imicola from Portugal, Rhodes, Israel, and South Africa and four other species of the Imicola Complex from southern Africa, and to estimate levels of matrilineal subdivision in C. imicola between Portugal and Israel. Eleven haplotypes were detected in C. imicola, and these formed one well-supported clade in maximum likelihood and Bayesian trees implying that the C. imicola samples comprise one phylogenetic species. Molecular variance was distributed mainly between Portugal and Israel, with no haplotypes shared between these countries, suggesting that female-mediated gene flow at this scale has been either limited or non-existent. Our results provide phylogenetic evidence that C. imicola in the study areas are potentially competent AHS and BT vectors. The geographical structure of the C. imicola COI haplotypes was concordant with that of BT virus serotypes in recent BT outbreaks in the Mediterranean basin, suggesting that population subdivision in its vector can impose spatial constraints on BT virus transmission. 相似文献
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The desert woodlouse Hemilepistus reaumuri is one of the most abundant macroscopic invertebrates in North Africa, the Arabian steppes, semi-desert and desert, and the Negev desert Israel.The main purposes of our study were: 相似文献
13.
S. pombe aurora kinase/survivin is required for chromosome condensation and the spindle checkpoint attachment response 总被引:9,自引:0,他引:9
The spindle checkpoint inhibits anaphase until all chromosomes have established bipolar attachment. Two kinetochore states trigger this checkpoint. The absence of microtubules activates the attachment response, while the inability of attached microtubules to generate tension triggers the tension/orientation response. The single aurora kinase of budding yeast, Ipl1, is required for the tension/orientation, but not attachment, response. In contrast, we find that the single aurora kinase of fission yeast, Ark1, is required for the attachment response. Having established that the initiator codon assigned to ark1(+) was incorrect and that Ark1-associated kinase activity depended upon survivin function and phosphorylation, we found that the loss of Ark1 from kinetochores by either depletion or use of a survivin mutant overides the checkpoint response to microtubule depolymerization. Ark1/survivin function was not required for the association of Bub1 or Mad3 with the kinetochores. However, it was required for two aspects of Mad2 function that accompany checkpoint activation: full-scale association with kinetochores and formation of a complex with Mad3. Neither the phosphorylation of histone H3 that accompanies chromosome condensation nor condensin recruitment to mitotic chromatin were seen when Ark1 function was compromised. Cytokinesis was not affected by Ark1 depletion or expression of the "kinase dead" ark1.K118R mutant. 相似文献
14.
Ido Izhaki 《Ostrich》2013,84(2):213-217
Izhaki, I. 1994. Preliminary data on the importance of Israel for the conservation of the White Pelican Pelecanus onocrotalus L. Ostrich 65:213-217. The majority of the western Palaearctic populations of the Great White Pelican Pelecanus onocrotalus stop over in Israel during their autumn migration. The annual average number of pelicans observed over Israel in autumn was 71,421±5,027. Although most of these birds were transient over Israel, increasing numbers of individuals (1130±303, between 1990 and 1993) stay and winter in the northern part of Israel. The natural feeding sites for pelicans were diminished during recent decades due to human activities such as the drainage of the Hula swamp in northern Israel 40 years ago. However, intensive fishery and aqua-culture sites became their favourite feeding laces either during migration or in winter. The fish industry complained that the birds seriously affect fish yield. The pelicans not only cause direct damage to the fix industry by predation, but they also transfer nematodes to fish (Oreochromis sp.). As et. there is no solution to the problem of these parasitic nematodes. This preliminary study revealed that the average daily fish consumption per individual was 0,52kg and the small sample size did not indicate any selection for certain fish species or size. Flight range estimation indicated that the pelicans, especially the weak individuals, nee xo feed during their stopover in Israel or in the relatively rare appropriate feeding sites along their southward migratory route over the desert in order to reach their wintering areas in eastern central Africa. 相似文献
15.
Canine carnassials: character displacement in the wolves, jackals and foxes of Israel 总被引:1,自引:0,他引:1
TAMAR DAYAN DANIEL SIMBERLOFF EITAN TCHERNOV YORAM YOM-TOV 《Biological journal of the Linnean Society. Linnean Society of London》1992,45(4):315-331
Previous research implies that competitive character displacement in felids and mustelids of Israel is expressed by canine size. Anatomy and observed killing behaviour of canids suggest that canines in this group are less adapted for the stylized role they play in felids and mustelids. Thus we hypothesized that character displacement, if it exists in canids, should not be manifested more clearly by canine size than by other traits. Five sympatric and at least partially syntopic canids occupy Israel, while in North Africa the largest (wolf) and smallest (Blanford's fox) are absent. Sexual size dimorphism in Israeli canids is generally less than in felids and mustelids (in which we analysed each sex as a separate ‘morphospecies’), so we used mixed-sex samples to represent each species. The three largest species (wolf, golden jackal and red fox) are also represented by Middle Palaeolithic samples in Israel, and all three had larger carnassial lengths then. Carnassial lengths, canine diameters and skull lengths are all remarkable evenly spaced among the five recent species in Israel. In Egypt, no trait manifests significant equality. Despite regional fluctuations in size, the carnassial length ratios of the three smaller species (foxes) are strikingly constant (1.18–1.21) throughout the region, while the ratios for the three larger species (wolf, jackal and red fox), sympatric only in Israel, are larger (1.33–1.34). Finally, mean carnassial length of jackals is constant across North Africa, while skull length and canine diameter both increase from Algeria through Egypt. All three traits are larger in Egypt than in Israel. We tentatively ascribe the equal ratios in Israel to competitive character displacement, though this hypothesis is speculative because of numerous lacunae in knowledge of diet, killing behaviour, available resources and extent of food limitation. Furthermore, humans have greatly affected range, density and ecology of wolves and jackals in the last century. Larger sizes in the Palaeolithic may well be manifestations of Bergmann's rule. The constancy of carnassial length in North African jackals, notwithstanding a longitudinal cline in CBLs of these populations, and the constant ratio between jackal and red fox carnassial length are both consistent with a hypothesis of character release in the absence of the wolf. 相似文献
16.
The Great White Pelican Pelecanus anocrotalus is the largest migrating bird in Israel and is an endangered species. The Palearctic populations of the Great White Pelican breed in eastern Europe and Asia and most of them pass through the ‘bottleneck’ of Israel to wintering grounds in Africa. Natural feeding sites for pelicans have diminished during recent decades due to human activities, and sites of extensive aquaculture have become the favourite feeding places for wintering and migrating Great White Pelicans. The fish industry has reported a significant impact on fish yield and the conflict between pelicans and fishermen has escalated so that hundreds of pelicans have died in recent years from shooting or accidental electrocution. We approached this management problem by studying the energy requirements of the Great White Pelican during migration and while wintering in Israel, under different feeding regimes (fish or chicks) and in different seasons, in captivity. The results show that a captive bird consumes 1.1 kg of fish per day. The basal metabolic rate and apparent metabolized energy of the Great White Pelican are both higher than predicted from allometric equations. Energetic demands were quite stable on both diets (fish and chicks) and during both seasons (winter and summer). The fat deposits of migrating pelicans averaged 313.5 g compared with 480 g in wintering birds (3.4% and 5.4% of body mass, respectively). Based on these fat contents and on the measured daily energy consumption, we calculated that birds that do not feed in Israel can fly only up to 1620 km from Israel southward and could not cover the distance to their likely wintering grounds in the Sudd area in southern Sudan. However, birds that replenish their fuel reserves could fly up to 2460 km and hence could reach this area. Therefore, we conclude that Great White Pelicans must feed in Israel during the autumn migration in order to complete their journey to Africa. One solution to the conflict between pelicans and fishermen could be to combine deterrents preventing pelicans from feeding in fish‐ponds with the provision of attractive alternative reservoirs, to ensure regular food supplies during autumn. 相似文献
17.
The overwintering potential of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann) (Diptera: Tephritidae), in cold winter areas within its northern distribution is a key element in understanding its ecology. Recent studies have suggested that although originating in tropical Africa, the fly has become adapted to the cold weather that prevails within its northernmost areas of distribution. We address the question of whether the Mediterranean fruit fly has expanded its overwintering range to include the mountains of central Israel. Doing so would imply that the fly has developed either a behavioral or a physiological mechanism to cope with low temperature and/or damp conditions in combination with cold. We monitored adult populations year round, sampling fruit, calculating expected emergence days for overwintering flies, and studying adults captured within dense and sparse apple orchards. We also performed several manipulative experiments to study preimago ability to survive the winter under natural or seminatural conditions. The study was conducted in the central mountains of Israel at 700-m altitude from 1994 to 2003. Comparison experiments also were conducted at 400 m and at sea level. Our results show 1) no adults captured during the winter and spring, 2) an absence of new infestations during the winter and spring, and 3) inability of preimago stages to overwinter in the central mountains of Israel. Thus, we conclude that the fly does not overwinter in the central mountains of Israel. We discuss the ecological and applied significance of our findings. 相似文献
18.
Analysis of the serotype-specific epitopes of avian infectious bronchitis virus strains Ark99 and Mass41. 总被引:1,自引:0,他引:1
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The Ark and Mass serotype-specific epitopes of infectious bronchitis virus were studied by immunofluorescence and immunoprecipitation of mutant and recombinant spike glycoproteins (S protein) expressed in mouse L cells. Serotype-specific monoclonal antibodies could bind to the recombinant proteins of Ark99 and Mass41 expressed from the chimeras in which the N-terminal thirds of the S1 sequences were reciprocally exchanged. Therefore, it appears that the respective serotype-specific epitopes of both strains were localized within the C-terminal two-thirds of the S1 proteins. Deletion and insertion of a five-amino-acid fragment on the S1 proteins of Ark99 and Mass41, altered the serotype-specific epitopes. This result implies that the five-amino-acid insertion on the S1 protein of the Ark serotype was involved in determining the conformation of the protein, probably acting as a spacer. In addition, it appears that an interaction between sequences of the N-terminal third and the remaining portion of the S1 protein determines the tertiary structure of the protein as well as the conformation of the serotype-specific epitope. 相似文献
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《Austral ecology》2000,25(6):689-690
Book reviewed in this article: The Australian Ark: a History of Domesticated Animals in Australia Ian Parsonson. Australian Ants: Their Biology and Identification Steve Shattuck. 相似文献