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1.
为了研究藏药臭蚤草的浩性成分,我们利用各种柱色谱技术,从藏药臭蚤草甲醇提取物的乙酸乙酯萃取相分离到4个化合物,通过1D、2DNMR、MS和HRMS等试验,鉴定为2,4-dihydroxy-6-methyl—ethanone-4-O-β-D—Glc(1),4-(3’-hydroxypropyl)-2,6-dimethoxyphenol-3’-O-β-D—glcoside(2),4-allyl-2-methoxyphenol-1-O-β-gleo—side(3),2-methyl-1,3,6-trihydroxy-9,10-anthraquinone-3—O-(6'-O-Ac)-α—L—Rha-(1→2)-β-D—Gle(4),其中化合物1—3为苯丙素苷类化合物,化合物4为蒽醌苷。化合物1—4都是首次从该属植物中分离得到,化合物1为新的苯丙素苷类化合物。 相似文献
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夏至草亲水性化学成分的研究 总被引:2,自引:0,他引:2
从夏至草正丁醇萃取物中分离得到6个化合物,运用光谱技术和化学方法鉴定了其中5个化合物的结构,其中1个为无机化合物KNO3(La1)另外4个为苯丙素甙,分别为purpureaside(La2),acteoside(La3),cistanoside B(La4),jionosideA(La5),均为首次从该属植物中获得。 相似文献
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从无柄新乌檀乙醇浸膏的正丁醇部位分离得到7个已知配糖体化合物,经波谱分析为:喹诺酸-3-O-β-D-葡萄吡喃糖基(28→1)-β-D-葡萄吡喃糖酯(1),齐墩果酸-(28→1)-β-D-葡萄吡喃糖酯(2),熊果酸-(28→1)-β-D-葡萄吡喃糖酯(3),喹诺酸-3-O-β-D-葡萄吡喃糖基-(1→3)-6-去氧-β-葡萄吡喃糖苷(4),齐墩果酸-3-O-β-D-吡喃木糖基-(1→2)-β-D-葡萄吡喃糖基-28-O-β-D-葡萄吡喃糖酯(5),番木鳖甙(6),7-甲氧基-龙胆苦甙(7)。这些化合物均为首次从该属中分离得到。 相似文献
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Phenolic glycosides from Phagnalon rupestre 总被引:2,自引:0,他引:2
Analysis of the butanol-soluble fraction from the methanolic extract of the aerial parts of Phagnalon rupestre (Asteraceae) has led to the isolation of seven phenolic compounds. Three have been identified on the basis of their NMR spectra as new natural compounds: the lignan 7,7'-bis-(4-hydroxy-3,5-dimethoxyphenyl)-8,8'-dihydroxymethyl-tetrahydrofuran-4-O-beta-glucopyranoside (1), the prenylhydroquinone glycoside 1-O-beta-glucopyranosyl-1,4-dihydroxy-2-(3'-hydroxy-3'-methylbutyl) benzene (2) and the acetophenone glycoside 12-O-beta-glucopyranosyl-9beta,12-dihydroxytremetone (3). The known flavonoids apigenin-7-O-beta-glucoside, luteolin-7-O-beta-glucoside, luteolin-7-O-beta-glucuronide and the acetophenone picein were also isolated. 相似文献
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Abstract: To search for new and bioactive compounds from traditional Chinese medicines, a new glycoside, 3-O-[α- L -rhamnopyranosyl-(1→3)-( n -butyl-β- D -glucopyranosiduronate)]-28-O-β- D -glucopyranosyloleanolic acid ( 1 ), was isolated from the roots of Cyathula officinalis Kuan, along with 3-O-(methyl-β- D -glucopyranosiduronate)-28-O-β- D -glucopyranosyl oleanolic acid ( 2 ), 3-O-β- D -glucopyranosyl oleanolic acid ( 3 ), 3-O-β- D -glucuronopyranosyl oleanolic acid ( 4 ), 3-O-[β- L -rhamnopyranosyl-(1→3)-(β- D -glucuronopyranosyl)] oleanolic acid ( 5 ), 3-O-(β- D -glucuronopyranosyl)-28-O-β- D -glucopyranosyl oleanolic acid ( 6 ), 28-O-β- D -glucuronopyranosyl-(1→4)-β- D -glucopyranosyl hederagenin ( 7 ), 3-O-[β- L -rhamnopyranosyl-(1→3)-β- D -glucuronopyranosyl]-28-O-β- D -glucopyranosyl oleanolic acid ( 8 ), and 3-O-[β- D -glucopyranosyl-(1→2)-α- L -rhamnopyranosyl-(1→3)-β- D -glucuronopyranosyl]-28-O-β- D -glucopyranosyl oleanolic acid ( 9 ). The structures of these compounds were determined based on spectral and chemical evidence. The 50 per cent growth-inhibiting (GI50 ) of compounds 1 and 5 against MDA-MB-231 (a human breast cancer cell line) was 3.44 × 10-4 and 4.66 × 10-4 mol/L, respectively.
(Managing editor: Wei WANG) 相似文献
(Managing editor: Wei WANG) 相似文献
7.
The structure and antioxidant properties of a new natural glycoside, trichotomoside (1), isolated from Clerodendron trichotomum, were investigated. Trichotomoside was identified as 2-(3-hydroxy-4-methoxyphenyl)ethyl 3-O-(2,3-di-O-acetyl-alpha-L-rhamnopyranosyl)-4-O-[(2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside. The compound was active towards intracellular reactive oxygen species (ROS) and exhibited DPPH-radical-scavenging effects. The radical-scavenging activity of 1 was found to protect the viability of Chinese hamster lung fibroblasts (V79-4 cells) exposed to H2O2 and gamma-irradiation. 相似文献
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从毛叶飞蛾藤(Porana racemosa Roxb.)全草的95%乙醇提取物中分离并鉴定了11个化合物,其中一新的C30甾体化合物鉴定为(22E,24ξ)-24-正丙基胆甾-7,22-二烯-3β-醇(飞蛾藤素,1).其余10个已知化合物分别为东莨菪素(2)、东莨菪苷(3)、伞形华内酯(4)、β-D-甲基吡喃果糖苷(5)、丁香脂素4-O-β-D-吡喃葡萄糖苷(6)、斛皮素-3-O-β-D-吡喃葡萄糖苷(7)、斛皮素-3-O-α-L-吡喃鼠李糖苷(8)、异泽兰黄素(9)、山奈素-3-O-β-D-吡喃葡萄糖苷(10)和(E)-N-2-(2,3-二羟基苯基)乙基肉桂酰胺(11). 相似文献
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In order to find new structural and biologically active compounds, the constituents from the whole plant of Drymaria diandra B1. (Caryophyllaceae) were investigated and three new flavone glycosides,named drymariatins B (1), C (2), and D (3), were isolated by solvent partition, Si gel, sephadex LH-20, and Rp-18 column chromatography. Using spectroscopic methods, including two-dimensional nuclear magnetic resonance analysis, the structures of these compounds were elucidated as 6-C-(2-deoxy-β-D-fucopyranosyl)-5,7,4'-trihydroxyl-flavone, 6-C-(2-deoxy-β-D-fucopyranosyl)-7-O-(β-D-glucopyranosyl)-5,4'-dihydroxylflavone, and 6-C-(3-keto-β-digitoxopyranosyl)-7-O-(β-D-glucopyranosyl)-5,4'-dihydroxyl-flavone. 相似文献
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Zhong-Tao DING Xue-Qiong YANG Qiu-E CAO Fei LI 《植物学报(英文版)》2005,47(9):1140-1144
In order to find new structural and biologically active compounds, the constituents from the whole plant of Drymaria diandra B1. (Caryophyllaceae) were investigated and three new flavone glycosides, named drymariatins B (1), C (2), and D (3), were isolated by solvent partition, Si gel, sephadex LH-20, and Rp- 18 column chromatography. Using spectroscopic methods, including two-dimensional nuclear magnetic resonance analysis, the structures of these compounds were elucidated as 6-C-(2-deoxy-β-D-fucopyranosyl)- 5,7,4'-trihydroxyl-flavone, 6-C-(2-deoxy-β-D-fucopyranosyl)-7-O-(β-D-glucopyranosyl)-5,4'-dibydroxyl- flavone, and 6-C-(3-keto-β-digitoxopyranosyl)-7-O-(β-D-glucopyranosyl)-5,4'-dihydroxyl-flavone. 相似文献
12.
A novel C30 sterol, (22E, 24ξ)-24-n-propylcholest-7, 22-dien-3β-ol (racemosol, 1), along withscopoletin (2), scopolin (3), umbelliferone (4), methylβ-D-frucopyranoside (5), syringaresinol-4-O-β-D-glucopyranoside (6), quercetin-3-O-β-D-glucopyranoside (7), quercetin-3-O-α-L-rhamnopyranoside (8),eupatilin (9), kaempferol-3-O-β-D-glucopyranoside (10) and (E)-N-2-(2,3-dihydroxyphenyl) ethyl cinnamamide(11), was isolated from the whole plants of Porana racemosa Roxb. Their structures were elucidatedpredominantly by spectral evidence. 相似文献
13.
秃杉中萜类和酚类化学成分 总被引:4,自引:0,他引:4
从秃杉(Taiwania flousiana Gaussen)的根皮中分离鉴定了6个三萜类化合物、1个二萜类化合物、1个倍半萜类化合物和9个酚类化合物,其中两个为新化合物,分别鉴定为 (24S)-3b-methoxy-5a-lanost-9(11)-ene-7b, 24,25-triol(1) 和senecrassidiol-9-O-b-D-glucopyranoside (8),化合物1命名为taiwaniatriol。通过波谱学方法确定了这些化合物的结构。 相似文献
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Two new penterpenoid saponins, hemsloside-Ma4 (1) hemsloside-Ma5 (2), and a new diterpenoid glycoside, hemsloside-Ma6 (3), were isolated from the rhizomes of Hemsleya chinensis. By detailed analysis of the NMR spectra and chemical methods, the structures of new compounds were determined to be 3-O-β-l-arabinopyranosyl-(1 → 3)-O-(6′-methyl ester)-β-d-glucuropyranosyl-oleanolic acid-28-O-β-d-glucopyranosyl-(1 → 6)-O-β-d-glucopyranoside (1), 3-O-β-l-arabinopyranosyl-(1 → 3)-O-(6′-methyl ester)-β-d-glucuropyranosyl-oleanolic acid-28-O-β-d-xylopyranosyl-(1 → 6)-O-β-d-glucopy-ranoside (2), and 13ϵ-hydroxylabda-8(17), 14-dien-18-oic acid-18-O-α-l-rhamnopyranosyl-(1 → 2)-O-β-d-glucopyranosyl-(1 → 4)-O-α-l-rhamnopyranoside (3). Diterpenoid-type compound (3) was isolated from Hemsleya genus for the first time. 相似文献
15.
从秃杉(Taiwania flousiana Gaussen)的根皮中分离鉴定了6个三萜类化合物、1个二萜类化合物、1个倍半萜类化合物和9个酚类化合物,其中两个为新化合物,分别鉴定为(24S)-3β-methoxy-5α-lanost-9(11)-ene-7β,24,25-trio1(1)和senecrassidiol-9-O-β-D-glucopyranoside(8),化合物1命名为taiwaniatriol.通过波谱学方法确定了这些化合物的结构. 相似文献
16.
Nguyen Xuan Cuong Le Thi Vien Le Hoang Tran Thi Hong Hanh Do Thi Thao Nguyen Van Thanh Nguyen Hoai Nam Do Cong Thung Phan Van Kiem Chau Van Minh 《Bioorganic & medicinal chemistry letters》2017,27(13):2939-2942
Using various chromatographic separation techniques, eight triterpene diglycosides (1–8), including four new compounds namely stichorrenosides A–D (1–4), were isolated from a methanol extract of the Vietnamese sea cucumber S. horrens. Their structures were elucidated based on spectroscopic analyses, including HR ESI MS, 1D and 2D NMR. Their in vitro cytotoxic activity against five human cancer cell lines, Hep-G2 (hepatoma cancer), KB (epidermoid carcinoma), LNCaP (prostate cancer), MCF7 (breast cancer), and SK-Mel2 (melanoma), was evaluated using SRB methods. Stichorrenoside D (4), stichoposide A (5), and 3β-O-[β-d-xylopyranosyl-(1→2)-β-d-xylopyranosyl]-23S-acetoxyholost-7-ene (7) showed strong cytotoxicity on all five tested cancer cell lines, whereas significant effect was observed for stichorrenoside C (3) and stichoposide B (6). 相似文献
17.
Cholestane glycosides, dioseptemlosides A (1) and B (2), together with six spirostane glycosides, dioseptemlosides C-H (3-8), were isolated from the rhizomes of Dioscorea septemloba. Their structures were established on the basis of physical data, spectroscopic analysis (HRESIMS, 1D and 2D NMR), and chemical methods. Spirostane aglcones containing hydroxyl group at C-7, as found in compounds 4-7, were reported in the family Dioscoreaceae for the first time. These compounds did not show considerable inhibitory anti-tumor activities at a concentration of 10 microM. 相似文献
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Two new glycosides, vanillic acid 4-O-β-d-(6′-O-(Z)-2′'-methylbut-2′'-enoate)glucopyranoside (1), p-methoxycarvacrol-6-O-β-d-glucopyranoside (2), along with two known analogues (3-4), were isolated from the leaves and rattan stems of Schisandra chinensis. The structures of these isolates were determined by UV, HRESIMS, 1D and 2D NMR spectral analyses. 相似文献