Trace metals in sea water. : C. S. Wong,Edward Boyle,Kenneth W. Bruland,J. D. Burton and Edward D. Goldberg. Nato Conference Series,Series IV: Marine Sciences,Volume 9, Plenum Press,New York and London,pp. xiv + 920, ISBN 0-306-41165-2, U.S. $ 115.00.

A comprehensive mechanism is proposed for the photolysis of transition metal complexes in equilibrium solutions. This involves the photo-oxidation, a possibility of energy transfer and several secondary thermal reactions, e.g. forward and back reactions with photochemically-formed H· radicals. The scheme includes the individual quantum yield (IQY) of each species. The photo-oxidations of FeSO₄, FeClO₄, FeCl₂ in aqueous acidic solutions were studied by continuous irradiation. The IQY of Fe_aq²⁺ (0.2), FeSo₄ (0.3), FeHSO₄⁺ (0.67), FeClO₄⁺ (0.06–0.2), FeCl⁺ (0.8), FeCl₂ (0.3) were determined. The IQY was found to be dependent on H⁺ concentration, due to competition with geminal recombination within the solvent cage. This dependence, and the efficiency of energy transfer between excited iron(III) species and iron(II) in ground state, are discussed.     

Thematic Minireview Series on Phospholipase D and Cancer

Phospholipase D (PLD) signaling plays a critical role in cell growth and proliferation, vesicular trafficking, secretion, and endocytosis. At the cellular level, PLD and its reaction product, phosphatidate, interact with a large number of protein partners that are directly related to the actin cytoskeleton and cell migration. Cancer invasion and metastasis rely heavily on cellular motility, and as such, they have put PLD at center stage in cancer research. This minireview series highlights some of the molecular mechanisms that provide evidence for the emerging tumorigenic potential of PLD, the role of the microenvironment, and putative connections with inflammation. PLD represents a potential target for the rational development of therapeutics against cancer and other diseases.     

Complex Biventricular Pacing - A Case Series

It is established that cardiac resynchronisation therapy (CRT) reduces mortality and hospitalisation and improves functional class in patients with NYHA class 3-4 heart failure, an ejection fraction of ≤ 35% and a QRS duration of ≥ 120ms. Recent updates in the American guidelines have expanded the demographic of patients in whom CRT may be appropriate. Here we present two cases of complex CRT; one with a conventional indication but occluded central veins and the second with a novel indication for CRT post cardiac transplant.     

Oceanography and Marine Environment of the Basque Country. Elsevier Oceanography Series 70. Edited by A. Borja and M. Collins (2004) Elsevier B.V., Amsterdam. ISBN 0-444-51581-X. ISSN 0422-9894 (Series).

This is not a book that you probably start reading from thefirst page. Its 24 review chapters have informative titles andare organised in seven sections that together with a four-pagelocation index and an eight-page subject index invites you todive for your favourite subjects. The editors have succeededto structure the book in ways that makes easy navigation amongstits