Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry

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Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasis

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Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow

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Molecular and functional architecture of striatal dopamine release sites

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3β-Hydroxysteroid dehydrogenase expressed by gut microbes degrades testosterone and is linked to depression in males

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Gut-microbiome-expressed 3β-hydroxysteroid dehydrogenase degrades estradiol and is linked to depression in premenopausal females

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Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation

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Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes

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Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations

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IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance

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Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension

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Evidence for a clathrin-independent endocytic pathway for APP internalization in the neuronal somatodendritic compartment

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TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease

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CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis

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Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK

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Egg-Surface Bacteria Are Indirectly Associated with Oviposition Aversion in Bactrocera dorsalis

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Guidance by followers ensures long-range coordination of cell migration through α-catenin mechanoperception

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Conformational change of α-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson’s disease

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β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia

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Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity

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