共查询到20条相似文献,搜索用时 31 毫秒
1.
Sevgi Ertuğrul Karatay Ülküye Dudu Gül Gönül Dönmez 《Preparative biochemistry & biotechnology》2013,43(7):653-662
Methylene blue (MB) biosorption properties of Rhizopus arrhizus were investigated in the presence of surfactants. The effects of cationic and anionic surfactants on MB removal by dead biomass (1 g L?1) were determined. MB removal was tested as a function of initial pH (2–12), contact time (5–1440 min), and dye (37.4–944.7 mg L?1) and surfactant (0–10 mM) concentrations. The opposite charged anionic surfactant dodecylbenzenesulfonic acid sodium salt (DBS) enhanced sorption of cationic MB by biomass dramatically. Maximum biosorption capacity was 471.5 mg g?1 at pH 8 with 0.5 mM DBS at 944.7 mg L?1 MB concentration. The surfactant-stimulated fungal decolorization method may provide a highly efficient, inexpensive, and time-saving procedure in biological wastewater treatment technologies. 相似文献
2.
Mónica Patrón-Prado Pablo Lodeiro Daniel B. Lluch-Cota Elisa Serviere-Zaragoza Margarita Casas-Valdez Tania Zenteno-Savín Lía Méndez-Rodríguez 《Journal of applied phycology》2013,25(6):1933-1937
The efficiency of batch and continuous systems of copper removal by Sargassum sinicola was studied. The effects of flow rate, initial metal concentration, and bed density on the capacity of the continuous system were also recorded. In batch systems, the maximum biosorption capacity was calculated as 49.63?±?0.88 mg g?1; in the continuous system, under the following conditions: flow rate of 10 mL min?1, initial solution of 200 mg Cu L?1, bed density of 150 g L?1, and higher copper removal of 62.39?±?1.91 mg g?1 was achieved. The Thomas model can be used to predict the breakthrough curves, but it underestimated breakthrough time. 相似文献
3.
Two species of cyanobacteria, Oscillatoria laete-virens (Crouan & Crouan) Gomont and Oscillatoria trichoides Szafer, were isolated from a polluted environment and studied for their Cr6+ removal efficiency from aqueous solutions. The parameters studied included the solution pH, contact time, initial concentration of Cr6+ and culture density. Living biomass is more efficient than dead biomass in Cr6+ removal. Removal by living biomass involves bioreduction and biosorption. Below pH 3.1, bioreduction is favored and biosorption is dominant at higher pH. The highest removal through biosorption for living biomass was achieved between pH 5 and 5.9 and for dead biomass at pH 2. The maximum removal was on the tenth day of exposure for both the species. Cr6+ removal increased from 0.2 to 0.4 g L?1 of culture biomass with a decrease with further increase in biomass. Increased Cr6+ concentration decreases growth of both the species over time. Both species tolerate a concentration as high as 30 mg L?1 Cr6+. There was no evidence of bioreduction in the case of dead biomass. Living biomass of O. laete-virens followed both Langmuir and Freundlich models with maximum sorptive capacity (q max) of 21.88 mg g?1. The results of dead biomass were well fitted only to Langmuir isotherm. O. trichoides living biomass did not follow either of the isotherms, but removed the metal to a maximum extent of 38.7mg g?1. The removal was better described by Freundlich isotherm in case of dead biomass. The pseudo-first-order model describes the kinetics better than the pseudo-second-order model in the case of living biomass. Participation of carboxylic, carbonyl, and amino groups in Cr6+ removal was confirmed by FTIR analysis. Both species seem to be promising biosorbents for Cr6+. 相似文献
4.
Chou-Fei Wu Xiao-Ming Xu Qing Zhu Mao-Cheng Deng Lei Feng Juan Peng Jian-Ping Yuan Jiang-Hai Wang 《Applied microbiology and biotechnology》2014,98(8):3801-3807
The biodetoxification of cyanide-rich wastewater has become increasingly popular because of its cost-effectiveness and environmental friendliness. Therefore, we have developed an effective method, optimised by response surface methodology, for detoxifying cyanide-rich wastewater using Bacillus sp. CN-22, which was newly isolated from a cyanide-contaminated electroplating sludge and could tolerate a CN? concentration of 700 mg L?1. The concentration of CN? in the treated wastewater decreased from 200 to 6.62 mg L?1 after cultivation with 2.38 % inocula for 72 h on the medium, consisting of 0.05 % KH2PO4, 0.15 % K2HPO4, 1.0 mM MgCl2, 1.0 mM FeCl3, 0.1 % NH4Cl, and 0.1 % glycerol. The CN? degradability of 96.69 % is similar to the predicted value of 96.82 %. The optimal cultivation conditions were controlled as follows: initial pH, 10.3; temperature, 31 °C; and rotary speed, 193 rpm. The maintenance of higher pH in the overall treatment procedures may avoid the production of volatile HCN and the risk associated with cyanide detoxification. Additionally, the bacterial strain Bacillus sp. CN-22, with its potent cyanide-degrading activity at the initial CN– concentration of 200 mg L?1, may be employed to effectively treat cyanide-rich wastewater, especially electroplating effluent. 相似文献
5.
Alejandro Zepeda Chérif Ben-Youssef Susana Rincón Flor Cuervo-López Jorge Gómez 《Biodegradation》2013,24(3):377-385
The kinetic behavior, oxidizing ability and tolerance to m-cresol of a nitrifying sludge exposed to different initial concentrations of m-cresol (0–150 mg C L?1) were evaluated in a sequencing batch reactor fed with 50 mg NH4 +-N L?1 and operated during 4 months. Complete removal of ammonium and m-cresol was achieved independently of the initial concentration of aromatic compound in all the assays. Up to 25 mg m-cresol-C L?1 (C/N ratio of 0.5), the nitrifying yield (Y-NO3 ?) was 0.86 ± 0.05, indicating that the nitrate was the main product of the process; no biomass growth was detected. From 50 to 150 mg m-cresol-C L?1 (1.0 ≤ C/N ≤ 3.0), simultaneous microbial growth and partial ammonium-to-nitrate conversion were obtained, reaching a maximum microbial total protein concentration of 0.763 g L?1 (247 % of its initial value) and the lowest Y-NO3 ? 0.53 ± 0.01 at 150 mg m-cresol-C L?1. m-Cresol induced a significant decrease in the values of both specific rates of ammonium and nitrite oxidation, being the ammonium oxidation pathway the mainly inhibited. The nitrifying sludge was able to completely oxidize up to 150 mg m-cresol-C L?1 by SBR cycle, reaching a maximum specific removal rate of 6.45 g m-cresol g?1 microbial protein-N h?1. The number of SBR cycles allowed a metabolic adaptation of the nitrifying consortium since nitrification inhibition decreased and faster oxidation of m-cresol took place throughout the cycles. 相似文献
6.
The present study investigated growth and biodegradation of 4-bromophenol (4-BP) by Arthrobacter chlorophenolicus A6 in batch shake flasks as well as in a continuously operated packed bed reactor (PBR). Batch growth kinetics of A. chlorophenolicus A6 in presence of 4-BP followed substrate inhibition kinetics with the estimated biokinetic parameters value of μ max = 0.246 h?1, K i = 111 mg L?1, K s = 30.77 mg L?1 and K = 100 mg L?1. In addition, variations in the observed and theoretical biomass yield coefficient and maintenance energy of the culture were investigated at different initial 4-BP concentration. Results indicates that the toxicity tolerance and the biomass yield of A. chlorophenolicus A6 towards 4-BP was found to be poor as the organism utilized the substrate mainly for its metabolic maintenance energy. Further, 4-BP biodegradation performance by the microorganism was evaluated in a continuously operated PBR by varying the influent concentration and hydraulic retention time in the ranges 400–1,200 mg L?1 and 24–7.5 h, respectively. Complete removal of 4-BP was achieved in the PBR up to a loading rate of 2,276 mg L?1 day?1. 相似文献
7.
Hamid Forootanfar Mojtaba Shakibaie Zahra Bagherzadeh Marzieh Aghaie-Khozani Nastaran Nafissi-Varcheh Hamid Reza Monsef-Esfahani Mohammad Ali Faramarzi 《Journal of applied phycology》2013,25(1):51-57
The present study aimed at evaluating the ability of some isolated cyanobacterial and microalgal strains for the removal of ρ-chlorophenol (ρ-CP), an environmentally harmful contaminant. To identify the most efficient species, a screening program was carried out using 15 microalgal and cyanobacterial strains. Among them, Tetraselmis suecica was able to remove 67 % of the ρ-chlorophenol at an initial concentration of 20 mg L?1 from the medium within a 10-day period. The efficacy of the process was dependent on the ρ-chlorophenol concentration. At concentrations above 60 mg L?1 of the pollutant, no removal was observed due to the inhibitory effect of ρ-chlorophenol on the T. suecica cells. The effect of cell immobilization in alginate beads on T. suecica removal capacity was also examined. Using this technique, the removal efficacy for the initial ρ-CP concentration of 20 mg L?1 increased up to 94 %. 相似文献
8.
Higher lipid production and nutrient removal rates are the pursuing goals for synchronous biodiesel production and wastewater treatment technology. An oleaginous alga Chlorella sp. HQ was tested in five different synthetic water, and it was found to achieve the maximum biomass (0.27 g L?1) and lipid yield (41.3 mg L?1) in the synthetic secondary effluent. Next, the effects of the stationary phase elongation and initial nitrogen (N) and phosphorus (P) concentrations were investigated. The results show that the algal characteristics were affected apparently under different N concentrations but not P, which were verified by Logistic and Monod models. At the early stationary phase, the algal biomass, lipid and triacylglycerols (TAGs) yields, and P removal efficiency increased and reached up to 0.19 g L?1, 46.7 mg L?1, 14.3 mg L?1, and 94.3 %, respectively, but N removal efficiency decreased from 86.2 to 26.8 % under different N concentrations. And the largest TAGs yield was only 6.4 mg L?1 and N removal efficiency was above 71.1 % under different P concentrations. At the late stationary phase, the maximal biomass, lipid and TAGs yields, and P removal efficiencies primarily increased as the initial N and P concentrations increase and climbed up to 0.49 g L?1, 99.2 mg L?1, 54.0 mg L?1, and 100.0 %, respectively. It is concluded that stationary phase elongation is of great importance and the optimal initial N/P ratio should be controlled between 8/1 and 20/1 to serve Chlorella sp. HQ for better biodiesel production and secondary effluent purification. 相似文献
9.
Khuong Quoc Nguyen Duangporn Kantachote Jumpen Onthong Ampaitip Sukhoom 《Annals of microbiology》2018,68(4):217-228
This research aimed to evaluate the capacity of acid-resistant purple nonsulfur bacteria, Rhodopseudomonas palustris strains VNW02, TLS06, VNW64, and VNS89, to resist Al3+ and Fe2+ and to investigate their potential to remove both metals from aqueous solutions using exopolymeric substances (EPS) and biomasses. Based on median inhibition concentration (IC50), strain VNW64 was the most resistant to both metals under conditions of aerobic dark and microaerobic light; however, strain TLS06 was more resistant to Al3+ under aerobic dark conditions. High metal concentrations resulted in an altered cellular morphology, particularly for strain TLS06. Metal accumulation in all tested PNSB under both incubating conditions as individual Al3+ or Fe2+ was in the order of cell wall?>?cytoplasm?>?cell membrane. This was also found in a mixed metal set only under conditions of aerobic dark as microaerobic light was in the degree of cytoplasm?>?cell wall?>?cell membrane. Of all strains tested, EPS from strain VNW64 had the lowest carbohydrate and the highest protein contents. Metal biosorption under both incubating conditions, EPS produced by strains VNW64 and TLS06, achieved greater removal (80 mg Al3+ L?1 and/or 300 mg Fe2+ L?1) than their biomasses. Additionally, strain VNW64 had a higher removal efficiency compared to strain TLS06. Based on the alteration in cellular morphology, including biosorption and bioaccumulation mechanisms, R. palustris strains VNW64 and TLS06 demonstrated their resistance to metal toxicity. Hence, they may have great potential for ameliorating the toxicity of Al3+ and Fe2+ in acid sulfate soils for rice cultivation. 相似文献
10.
A new strain of cyanobacteria was isolated from seawater samples collected near Jimo hot springs, Qingdao, China, and was identified as Cyanobacterium aponinum by 16S rDNA analysis. This study examined the effects of temperature, pH, light quality and high CO2 concentration on the growth of the cyanobacteria. Results showed that the strain exhibited a higher growth rate (about 168.4 mg L?1 day?1) at 35 °C than other temperatures (surviving at up to 50 °C) and a wide growth tolerance to acidic stress (pH 3.0 to 4.0) resulting from either H2SO4 or HNO3. The four light qualities, ranked by greatest to least biomass effect, were as follows: LED white light (LW) > LED red light (LR) > fluorescent white light (FW) > LED blue light (LB), achieving a higher lighting effect at a LW light intensity (60 μmol photons m?2 s?1) lower than other light qualities, which implied less energy consumption therewith. This strain demonstrates excellent CO2 tolerance at least 10% CO2 with the highest productivity in biomass (about 337.8 mg L?1 day?1) measured at 1% CO2 level. Results indicate that this strain is a promising candidate for use in biofixation of CO2 from flue gases emitted by thermoelectric plants. 相似文献
11.
12.
Muhammad Faizan A. Shukor Ismanizan Ismail Zamri Zainal Normah Mohd Noor 《Acta Physiologiae Plantarum》2013,35(5):1675-1689
Polygonum minus has been reported to contain valuable metabolites and to date, there is no report on using cell culture technique for metabolite production in P. minus. Naphthalene acetic acid (NAA) concentrations in the range of 2–6 mg L?1 were used in a matrix of combinations with dichlorophenoxyacetic acid (2,4-D) concentrations in the range of 2–10 mg L?1 as plant growth regulators (PGRs) to induce callus cultures. Media that were supplemented with 2 mg L?1 2,4-D + 4 mg L?1 NAA, 2 mg L?1 2,4-D + 6 mg L?1 NAA and 6 mg L?1 2,4-D + 8 mg L?1 NAA were effective for callus induction (93.3 % of the explants produced callus). To establish cell culture, the best growth was obtained from medium that was supplemented with 1 mg L?1 2,4-D + 2 mg L?1 NAA. From a 1-g inoculum size, the fresh weight increases exponentially after 5–10 days of culture, and a 26.71 g maximum fresh weight was obtained after 25 days of culture. The cell culture medium was then analyzed using gas chromatography–mass spectrometry (GC–MS). Jasmonic acid (100, 50, 25 and 5 μM), salicylic acid (100, 50, 25 and 5 μM), yeast extract (500, 250 and 100 mg L?1) and glass beads were used in this research as elicitors. The cell cultures were then incubated with the different elicitors for 1, 2, 3 and 4 days. Several compounds with high peak area percentages were detected, including 2-furancarboxaldehyde, 5-hydroxymethyl, furfural, and 2-cyclopenten-1-one, 2-hydroxy. These results show the diversity of metabolites released by P. minus cell into the culture medium under control conditions. 相似文献
13.
14.
S. Revathi Lakshmi S. Parthibhan N. Ahamed Sherif T. Senthil Kumar M.V. Rao 《In vitro cellular & developmental biology. Plant》2017,53(1):64-72
Brachystelma glabrum Hook.f. is an endemic plant species of Eastern Ghats, India. In this study, efficient protocols for in vitro micropropagation, flowering, and tuberization of this plant were developed. Sterilized shoot tip and nodal explants were cultured on Murashige and Skoog (MS) medium supplemented with different plant growth regulators (PGRs) and additives for shoot induction and multiplication. Both shoot tip and nodal explants showed the best response (90 and 100%, respectively) on MS medium supplemented with thidiazuron (TDZ) at 1.0 mg L?1. The microshoots multiplied best on MS + TDZ (1.0 mg L?1) in combination with α-naphthaleneacetic acid (NAA) at 0.5 mg L?1 and coconut water (CW) at 25%. The highest number of in vitro flowers (4.0 flowers per microshoot) was observed on MS medium supplemented with a combination of N6-benzyladenine (BA) and indole-3-butyric acid (IBA), each at 1.5 mg L?1. In vitro-derived shoots produced aerial tubers on MS + TDZ (2.0 mg L?1) + IBA (0.5 mg L?1) and basal tubers on MS + TDZ at 2.0 mg L?1. In vitro shoots were best rooted on half-strength (½) MS + NAA at 0.5 mg L?1. The rooted plantlets were successfully acclimatized in pots with 70% survival after a hardening period of 1 mo. This protocol provides an effective method for the conservation of this endemic plant species. 相似文献
15.
Suneerat Ruangsomboon Ladda Wongrat Sakchai Choochote Monthon Ganmanee Atiya Saparnklang 《Journal of applied phycology》2013,25(3):905-911
Pb2+ adsorption by the living cyanobacterium, Phormidium angustissimum followed the Langmuir adsorption model, with the maximum adsorption capacity (q max ) of 295.4?±?13.8 mg g?1. This result suggests that P. angustissimum is a promising living biosorbent to remove Pb2+ from wastewaters. Living biosorbents are better able to remove Pb2+ from wastewater than dead biosorbents, however there are practical limitations for their use are encountered in extreme conditions such as low pH and high Pb2+ concentration. The feasibility of using cyanobacterium, P. angustissimum, as a living biosorbent for the extraction of Pb2+ from wastewater was studied by investigating its photosynthestic performance and tolerance under Pb2+ (0–5 mg ?L?1) contamination and low pH (pH?3–7). Decreased photosynthetic performance caused by Pb2+ contamination and low pH stress was detected in this study by means of a reduction of the maximum photochemical efficiency of PSII (Fv/Fm). Detoxification mechanisms of P. angustissimum on Pb2+ appeared to increase its intracellular polysaccharides (IPS), exocellular polysaccharides (EPS), and protein. Living P. angustissimum could increase the pH of the solution which resulted in Pb2+ precipitation. The unique ability of P. angustissimum to remove Pb2+ and to grow under toxic conditions, demonstrated herein, indicates that it is a promising living biosorbent for mildly acidic water contaminated with Pb2+ in bioremoval systems in the which pH is not lower than 5 and Pb2+ is not higher than 5 mg L?1. 相似文献
16.
Ali Mahdavi Khadijeh Khermandar Salman Ahmady Asbchin Reza Tabaraki 《International journal of phytoremediation》2014,16(6):582-592
To assess the potential of Pb+2 accumulation in different parts of Acacia victoria, one year old A. victoria seedlings were exposed to Pb2+(NO3)2 in 5 different concentrations: 0, 50, 250, 500 and 1000 (mg Pb2+ L?1) for 45 days. Subsequently, Pb2+ uptake was quantified in roots, shoots and leaves of the seedlings by Atomic Absorption Spectroscopy (AAS). In addition, some physiological parameters such as biomass production, shoots and roots length, plant appearance, tissue concentrations and chlorophyll content were examined. Tissue concentrations increased as Pb2+ concentration increased for A. victoria. The visible toxicity symptoms (chlorosis and necrosis) appeared only to the highest concentration (1000 mg Pb2+ L?1), resulting in photosynthesis decrease, plant height, root length and dry biomass reduction. Almost 70% (up to 3580 mg Kg?1 of dry tissue) from the Pb2+ was accumulated in the entire plant tissues was retained in the roots in the seedlings exposed to 1000 mg Pb2+ L?1. The seedlings accumulated between 403 to 913 mg Kg?1 of Pb2+ in shoots and 286 to 650 mg Kg?1 of Pb2+ in leaves at different treatments. Bioconcentration and translocation factors were determined 5.14 and 0.255, respectively. The results show that A. victoria is suitable for lead-phytostabilization in Pb2+-contaminated soil. 相似文献
17.
Noureddine El Messaoudi Abdellah Dbik Mohammed El Khomri Abderrahman Sabour Safae Bentahar Abdellah Lacherai 《International journal of phytoremediation》2017,19(11):1047-1052
This study investigated the biosorption of Congo Red (CR) from aqueous solution by Date stones (DS) of Phoenix dactylifera and jujube shells (JS) of Ziziphus lotus. Batch operations were carried out in the liquid phase to observe the effect of various experimental parameters such as contact time, pH, temperature, and initial dye concentration on removal of CR. The characteristics of the DS and JS were also examined by Fourier transform infrared analysis. The biosorption data of CR on DS and JS samples were well fitted with the Langmuir isotherm and pseudo-second kinetics model with a maximum biosorption amount of 45.08 mg g?1 for DS and 59.55 mg g?1 for JS at pH = 4, temperature of 50°C, and an initial concentration of 100–800 mg L?1 after 90 minutes of contact time. The outcomes indicated that DS and JS can be used as a good low-cost alternative for the treatment of effluents containing CR in water. 相似文献
18.
Huimei Cai Yangyang Dong Yeyun Li Daxiang Li Chuanyi Peng Zhengzhu Zhang Xiaochun Wan 《Acta Physiologiae Plantarum》2016,38(6):144
Tea (Camellia sinensis (L.) O. Kuntze) hyper-accumulates fluoride (F), mainly in the leaves. To understand how tea copes with the stress caused by F, we tracked photosynthesis, antioxidant defense, and cell ultrastructure under different F concentrations (0–50 mg L?1). High F (≥5 mg L?1) caused decreases in photosynthetic and chlorophyll fluorescence parameters. Activated oxygen metabolism was altered by F, as manifested in increasing lipid peroxidation, electrolyte leakage (EL), and accumulation of H2O2. The activities of ascorbate peroxidase (APX, EC 1.11.1.1) and catalase (CAT, EC 1.11.1.6) increased at 0–5 mg L?1 F, but sharply decreased less than 10–50 mg L?1 F. The activity of manganese superoxide dismutase (Mn-SOD, EC 1.15.1.1) decreased with increasing F concentration. Expression of genes encoding antioxidant enzymes were in accordance with their measured activities. The results suggest that the antioxidant enzymes in the tea plant can eliminate reactive oxygen species (ROS) at <5 mg L?1 F, but not at 20–50 mg L?1 F. High F increased the number of epidermal hairs on tea leaves and decreased the stomatal aperture, reducing water loss. The leaf cellular structure appeared normal under 1–50 mg L?1 F, although starch grains in chloroplast increased with increasing F. Proline and betaine play important roles in osmotic regulation in tea plant tolerating F stress. ROS scavenging and greater number of epidermal hairs are likely parts of the tea plant F-tolerance mechanism. 相似文献
19.
E. J. Raes A. Isdepsky K. Muylaert M. A. Borowitzka N. R. Moheimani 《Journal of applied phycology》2014,26(1):247-255
Microalgae cultivation systems can be divided broadly into open ponds and closed photobioreactors. This study investigated the growth and biomass productivity of the halophilic green alga Tetraselmis sp. MUR-233, grown outdoors in paddle wheel-driven open raceway ponds and in a tubular closed photobioreactor (Biocoil) at a salinity of 7 % NaCl (w/v) between mid-March and June 2010 (austral autumn/winter). Volumetric productivity in the Biocoil averaged 67 mg ash-free dry weight (AFDW) L?1 day?1 when the culture was grown without CO2 addition. This productivity was 86 % greater, although less stable, than that achieved in the open raceway pond (36 mg L?1 day?1) grown at the same time in the autumn period. The Tetraselmis culture in the open raceway pond could be maintained in semi-continuous culture for the whole experimental period of 3 months without an additional CO2 supply, whereas in the Biocoil, under the same conditions, reliable semi-continuous culture was only achievable for a period of 38 days. However, stable semi-continuous culture was achieved in the Biocoil by the addition of CO2 at a controlled pH of ~7.5. With CO2 addition, the volumetric biomass productivity in the Biocoil was 85 mg AFDW L?1 day?1 which was 5.5 times higher than the productivity achieved in the open raceway pond (15 mg AFDW L?1 day?1) with CO2 addition and 8 times higher compared to the productivity in the open raceway pond without CO2 addition (11 mg AFDW L?1 day?1), when cultures were grown in winter. The illuminated area productivities highlight an alternative story and showed that the open raceway pond had a three times higher productivity (3,000 mg AFDW m?2 day?1) compared to the Biocoil (850 mg AFDW m?2 day?1). Although significant differences were found between treatments and cultivation systems, the overall average lipid content for Tetraselmis sp. MUR-233 was 50 % in exponential phase during semi-continuous cultivation. 相似文献
20.
Minoo Moshtaghie Pedram Malekpouri Mohammad Reza Dinko Ali Asghar Moshtaghie 《Journal of physiology and biochemistry》2013,69(2):297-304
Due to the severe hazardous influences of lead (Pb2+) on iron-related diseases, the effects of Pb2+ on serum parameters associated with iron metabolism have been studied in this project. Male Wistar rats weighing 200–250 g were treated with Pb2+ for the short and long period of times. The animals received daily intraperitoneal injection of 100 mg Pb2+ kg?1 body weight (BW) for 5 days and 4 mg?kg?1 BW of Pb2+ for 30 and 45 days, respectively. The results show that when animals were treated with both low and high concentrations of Pb2+, serum iron concentration decreased markedly, by 23.2, 32.8, and 39.9 %, while the sera TIBC and transferrin concentrations increased significantly (p?<?0.05). Following short- and long-term exposures to Pb2+, the percentage of serum transferrin saturation was also decreased in comparison with the untreated control group (p?<?0.05). Concentrations of serum copper and ceruloplasmin following Pb2+ treatments also reduced significantly (p?<?0.05). The percentage of hematocrit and hemoglobin levels was reduced (p?<?0.05) in all Pb2+-treated animals in comparison with the controls. These results suggest that Pb2+ changes the serum parameters related to iron metabolism, which may play an important role in producing iron-related diseases. 相似文献