Cytologic diagnosis of Bartholin's gland adenocarcinoma

An adenocarcinoma of Bartholin's gland was diagnosed by a smear of a swollen lesion of the left vulva, with confirmation on the subsequent surgical specimen. This appears to be the second such case in which the diagnosis was established by cytologic examination of the smear. This rare tumor should be considered in patients presenting with vulvar swellings; cytologic examination can be useful in its early diagnosis, as demonstrated by this case.     

Cytologic diagnosis of primary adenocarcinoma of Bartholin's gland. A case report.

The cytologic and histologic findings in an extremely rare case of adenocarcinoma of Bartholin's gland are described. The tumor cells in scraping and fine needle aspiration smears were in clusters. The nuclei were oval to oblong, and some cells had a peripherally displaced nucleus. The chromatinic material was slightly increased, and some nuclei had prominent nucleoli. The cytoplasm was basophilic and abundant. Microcalcifications and psammoma bodies were numerous. The tentative diagnosis was primary adenocarcinoma of Bartholin's gland, based on the cytologic findings and location of the tumor. Similar findings were noted in the biopsy and surgical specimens.     

Cytologic diagnosis of schistosomiasis in routine urinary specimens. A case report

A voided urine specimen from a 29-year-old male living in New York was sent for cytologic study, which revealed five schistosome ova, two with terminal spines, and one free miracidium in a cytocentrifuge specimen. The patient, who had been in West Africa three years earlier, underwent cystoscopy, with the finding of bladder mucosal ulcerations. Subsequent cytologic specimens, bladder biopsy and wet-mount preparations established a diagnosis of Schistosoma haematobium infection, which was treated, apparently successfully, with Metrifonate. The case is presented to focus attention on the cytologic diagnosis of S. haematobium in routine urinary specimens since the opportunity to make such a diagnosis is increasing in the continental United States as more Americans visit areas of endemic infestation and more residents of those areas immigrate to this country.     

Reliable diagnosis of Trichosomoides crassicauda in the urinary bladder of the rat

Two reliable methods are described for identifying infection of laboratory rats with the nematode Trichosomoides crassicauda. The first is a rapid method where cryostat sections of the rat urinary bladder are stained with acridine orange and viewed under a fluorescence microscope. The second involves the stabilization of the bladder surface prior to examination using scanning electron microscopy (SEM).     

Cytologic diagnosis of adenovirus bronchopneumonia

The recognition of adenovirus-induced cytopathic changes in tracheal aspirates of two 7-month-old infants is reported. The smears showed cells containing nuclear inclusions with radiated strands ("rosette" cells), large homogeneously-staining nuclei ("smudge" cells) and nuclei with a "honeycomb" appearance. These findings appear to be distinctive for bronchopulmonary adenovirus infection, suggesting that the cytologic examination of tracheal aspirates may be a simple and cost-saving method for making an accurate diagnosis of this disease.     

Cytologic diagnosis of acanthamoebic keratitis

A case of acanthamoebic keratitis was identified from a corneal scraping stained with a modified Papanicolaou stain. The characteristic double-walled cyst forms were easily identified. Corneal scraping cytology provides a rapid, noninvasive means of diagnosis and follow-up for this serious disease.