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1.
Didier G. Arqués Jean-Paul Fallot Christian J. Michel 《Bulletin of mathematical biology》1998,60(1):163-194
The self-complementary subset
∪{AAA,TTT} with
= {AAC, AAT, ACC, ATC, ATT, CAG, CTC, CTG, GAA, GAC, GAG, GAT, GCC, GGC, GGT, GTA, GTC, GTT, TAC, TTC} of 22 trinucleotides
has a preferential occurrence in the frame 0 (reading frame established by the ATG start trinucleotide) of protein (coding)
genes of both prokaryotes and eukaryotes. The subsets
∪{CCC} and
∪{GGG} of 21 trinucleotides have a preferential occurrence in the shifted frames 1 and 2 respectively (frame 0 shifted by
one and two nucleotides respectively in the 5′-3′ direction).
and
are complementary to each other. The subset
contains the subset
which has the rarity property (6 × 10−8) to be a complementary maximal circular code with two permutated maximal circular codes
and
in the frames 1 and 2 respectively.
is called a C3 code.
A quantitative study of these three subsets
in the three frames 0, 1, 2 of protein genes, and the 5′ and 3′ regions of eukaryotes, shows that their occurrence frequencies
are constant functions of the trinucleotide positions in the sequences. The frequencies of
in the frame 0 of protein genes are 49, 28.5 and 22.5% respectively. In contrast, the frequencies of
in the 5′ and 3′ regions of eukaryotes, are independent of the frame. Indeed, the frequency of
in the three frames of 5′ (respectively 3′) regions is equal to 35.5% (respectively 38%) and is greater than the frequencies
and
, both equal to 32.25% (respectively 31%) in the three frames.
Several frequency asymmetries unexpectedly observed (e.g. the frequency difference between
and
in the frame 0), are related to a new property of the subset
involving substitutions. An evolutionary analytical model at three parameters (p, q, t) based on an independent mixing of the 22 codons (trinucleotides in frame 0) of
with equiprobability (1/22) followed by t ≈ 4 substitutions per codon according to the proportions p ≈ 0.1; q ≈ 0.1 and r = 1 − p − q ≈ 0.8 in the three codon sites respectively, retrieves the frequencies of
observed in the three frames of protein genes and explains these asymmetries. Furthermore, the same model (0.1, 0.1, t) after t ≈ 22 substitutions per codon, retrieves the statistical properties observed in the three frames of the 5′ and 3′ regions.
The complex behaviour of these analytical curves is totally unexpected and a priori difficult to imagine. 相似文献
2.
M. -T. Linossier D. Dormois R. Fouquet A. Geyssant C. Denis 《European journal of applied physiology and occupational physiology》1996,74(5):420-427
A group of 15 untrained male subjects pedalled on a friction-loaded cycle ergometer as fast as possible for 5–7 s to reach
the maximal velocity (V{immax}) against different braking forces (F
B). Power was averaged during a complete crank rotation by adding the power dissipated againstF
B to the power necessary to accelerate the flywheel. For each sprint, determinations were made of peak power output (
) power output attained atV
max (
) calculated as the product ofV
max andF
B and the work performed to reachV
max expressed in mean power output (
). The relationships between these parameters andF
B were examined. A biopsy taken from the vastus lateralis muscle and tomodensitometric radiographs of both thighs were taken
at rest to identify muscle metabolic and morphometric properties. The
value was similar for allF
B. Therefore, the average of values was defined as corrected maximal power (
). This value was 11 higher than the maximal power output uncorrected for the acceleration. Whereas the
determination did not require high loads, the highest
value (
) was produced when loading was heavy, as evidenced by the
-F
B parabolic relationship. For each subject, the braking force (
) giving
was defined as optimal. The
, equal to 0.844 (SD 0.108) N · kg−1 bodymass, was related to thigh muscle area (r = 0.78,P < 0.05). The maximal velocity (
) reached against this force seemed to be related more to intrinsic fibre properties (% fast twitch b fibre area and adenylate
kinase activity). Thus, from the
determination, it is suggested that it should be possible to predict the conditions for optimal exercise on a cycle ergometer. 相似文献
3.
Robert Rosen 《Bulletin of mathematical biology》1963,25(2):231-241
It has been shown in earlier work that one approach to what Rashevsky has called “abstract biology” is through the study of
the class of (
)-systems that can be formed in an arbitrary subcategory of the category of sets. The concept of the (
)-system, however, depends on the availability of mappings that contain other mappings in their range. It is shown that, by
introducing an appropriate measure for this property, the problem of characterizing those categories suitable for a rich theory
of (
)-systems reduces to a problem familiar from the general theory of graphs. Some new results in these directions are obtained,
and it is then shown that any category with mappings that possess properties we might expect to hold in the physical world
will also admit a rich theory of (
)-systems. In particular, it is shown that a sufficiently large family of mappings drawn at random from such a category will
with overwhelming probability contain an (
)-system.
This research was supported by the United States Air Force through the Air Force Office of Scientific Research of the Air
Research and Development Command, under Grant No. AF-AFOSR-9-63. 相似文献
4.
Evidence for four nonallelic structural genes for the γ chain of human fetal hemoglobin 总被引:4,自引:0,他引:4
T. H. J. Huisman W. A. Schroeder W. H. Bannister J. L. Grech 《Biochemical genetics》1972,7(2):131-139
An abnormal human fetal hemoglobin not only may be either aGγ- or anAγ-chain variant but also may be present in a different proportion of the total fetal hemoglobin.Gγ-Chain variants contribute either about one-fourth or one-eighth to the total production of HbF in the heterozygote, whereas
theAγ-chain variants approximate either one-eighth or one-sixteenth of the total HbF. These observations may indicate the presence
of four nonallelic Hbγ structural genes (termed
) which produce γ chains in an approximate ratio of 4 : 2 : 2 : 1. HbF Malta I is considered to be the product of a mutant
of the
locus, an undefined HbFx that of the
locus, HbF Hull and HbF Jamaica products of mutated
loci, and the newly discovered HbF Malta II a mutant of the
gene.
This work was supported in part by grants HL-05168 and HL-02558 from the National Institutes of Health, U.S. Public Health
Service. 相似文献
5.
Hugo M. Martinez 《Bulletin of mathematical biology》1966,28(3):411-416
IfN(t) is the expected number of cells in a culture at timet,
the corresponding time derivative, andf(t−τ)dt the probability that a cell of aget−τ at timet will divide in the succeeding time intervaldt, then according to Hirsch and Engelberg (this issue) there obtains the integral equation
for describing the dynamics of the cell population. It is the purpose of this note to give two alternative derivations of
this equation, one based on the age density equation of Von Foerster, and the other based on a generalized form of the Harris-Bellman
equation describing the first moment of an age dependent, branching process. In addition, a probability model is posed from
which the Von Foerster equation and, hence, the Hirsch-Engelberg equation readily follows. 相似文献
6.
Summary A set of three-dimensional triple-resonance experiments is described which provide
,
,
and
coupling constants. The pulse sequences generate E.COSY-like multiplet patterns and comprise a magnetization transfer from
the amide proton to the α-proton or vice versa via the directly bound heteronuclei. For residues with the 1Hα spin resonating close to the H2O signal, a modified HNCA experiment can be employed to measure the vicinal 1HN,1Hα couplings. Ambiguities associated with the conversion of
values into ϕ-angle constraints for protein structure determination can be resolved with the knowledge of the heteronuclear
3J-couplings. In favourable cases, stereospecific assignments of glycine α-protons can be obtained by employing the experiments
described here in combination with NOE data. The methods are applied to flavodoxin from Desulfovibrio vulgaris. 相似文献
7.
There are several explanations of why certain primitive multicellular organisms aggregate in particular forms and why their
constituent cells cooperate with one another to a particular degree. Utilizing the framework of formal language theory, we
have derived one possible simple classification of the volvocine algae—one of the primitive multicells—for some forms of aggregation
and some degrees of cooperation among cells. The volvocine algae range from the unicellular Chlamydomonas to themulticellular Volvox globator, which has thousands of cells. The classification we use in this paper is based on the complexity of Parikh sets of families
on Chomsky hierarchy in formal language theory. We show that an alga with almost no space closed to the environment, e.g.,
Gonium pectorale, can be characterized by
, one with a closed space and no cooperation, e.g., Eudorina elegans, by
, and one with a closed space and cooperation, e.g., Volvox globator, by
. This classification should provide new insights into the necessity for specific forms and degrees of cooperation in the
volvocine algae. 相似文献
8.
J. M. Bateman 《Bulletin of mathematical biology》1986,48(5-6):525-543
A theoretical study is made of three organ flow models with heterogeneity of capillary transit times. A new parametrization
of Rose and Goresky's Model III facilitates in many cases a reduction to Goresky's Model II, accomplished by a special time
shift. The shift parameter
defined here is critical in this analysis of Model III. A new expression of the series for outflow concentration in Model
III is given and proves useful in examining the model as an operator and in relating it to Models I and II. A result on parameter
optimization is given: if
then Model III cannot fit better than Model II. This is applied to some data from Rose and Goresky [Circulation Res.
39, 541–544 (1976)] and raises a new question about their model. A heart model of Levin and Bassingthwaighte based on regional
flow measurement is shown to be a discretized generalization of Model II.
This work supported in part by PHS Grant Nos. HL-19153 (SCOR for Pulmonary Vascular Disease) and HL-19370 at Vanderbilt University. 相似文献
9.
A small catchment on the Swedish West Coast has been studied over four years to determine S dynamics by using S isotope ratios. A Norway spruce dominated forest covers the catchment, and small peat areas occur in the lower parts of the catchment. The runoff
values varied both during the year, and from year to year. Over the period from February 1990 to December 1993, the
values ranged from — 1%. to +11%. Over the same period, the throughfall
values ranged from +1%. to +15%. There was no correlation (r
2= 0.01; Pr(F)=0.57) between
values in throughfall and runoff. Since the only input of S to the catchment is atmospheric deposition, the long-term runoff S mass flux is controlled by the deposition. Therefore, processes in the catchment are responsible for the variation in the runoff
values. During periods with
enriched runoff, bacterial dissimilatory SO
4
2–
reduction occurs in the catchment. After very dry periods, oxidation of this reduced S, which is32S-enriched, can be traced in runoff. Previous studies of the catchment have not been able to distinguish between: 1) oxidation of reduced S and dry deposition, and 2) reduction and adsorption. From the current study, it can be concluded that adsorption and dry deposition cannot cause the observed variation in runoff
. 相似文献
10.
Summary The complete sequence of the 5S rRNA from the bioluminescent bacterium,Beneckea harveyi has been determined to be p U G C U U G G C G
C C A U A G C G A
U U-G G A C C C A
C U G A (U) C U U C
A U U C C-G A A C
C A G A A G U G A
A C G A A U U A-G
G C C G A U G G U
G U G U G G G G C
U-C C C C A U G U
A G A G U A G G A
A U C G-C C A G G
U (U)OH.Two sites of sensitivity to ribonuclease T2 cleavage were identified; at A41 and either A54 or A55. Comparison with existing sequence information fromEscherichia coli andPhotobacterium phosphoreum clarifies the amount of diversity among the bioluminescent bacteria and provides further insight into their phylogenetic position. Sequence heterogeneities were encountered and the importance of these in interpreting 5S rRNA data is discussed. 相似文献
11.
Gregory K. Snyder Wesley W. Weathers 《Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology》1977,117(3):291-301
Summary Resting rates of O2 consumption
against
, exercise endurance times and
during recovery from vigorous exercise were measured inSceloporus occidentalis captured near sea level and inS. graciosus captured above 2850 m. Oxygen consumption against
was also measured inS. occidentalis captured above 2850 m. When
was recorded continuously, as ambient
was slowly reduced from 155 Torr, it became directly dependent upon ambient
between 110 and 120 Torr. The critical
for the high altitude lizards was lower than that for the lowland lizards, which enabled the former to maintain relatively higher
's when ambient
was reduced below 120 Torr. The high altitude lizards also had significantly greater endurance when stimulated to exercise at 1600 m (
130 Torr). Both the higher
under hypoxia and the greater endurance roughly parallel a significantly greater maximum
in the high altitude lizards. At a simulated altitude of 3600 m (
100 Torr), maximum
and rate of recovery of the O2 debt calculated from post active
were significantly reduced in the lowland but not the high altitude lizards. The effects of simulated altitude conditions on the lowland but not the mountaine animals indicate adaptations to altitude in these sceloporine lizards. We did not find any consistent relationship between organ/body weight ratios or hematocrit and our measures of
endurance or the altitude at which the lizards were captured. 相似文献
12.
Jack P. Hayes 《Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology》1989,159(4):453-459
Summary I compared the maximal aerobic metabolic rates (
), field metabolic rates (FMR), aerobic reserves (
-FMR), and basal metabolic rates (BMR) of wild and recently captured deer mice from low (440 m) and high (3800 m) altitudes. To separate the effects of the thermal environment from other altitudinal effects, I examined mice from different altitudes, but similar thermal environments (i.e., summer mice from high altitude and winter mice from low altitude). When the thermal environment was similar,
, FMR, and aerobic reserve of low and high altitude mice did not differ, but BMR was significantly higher at high altitude. Thus, in the absence of thermal differences, altitude had only minor effects on the aerobic metabolism of wild or recently captured deer mice.At low altitude, there was significant seasonal variation in
, FMR, and aerobic reserve, but not BMR. BMR was correlated with
, but not with FMR. The significant positive correlation of BMR with
indicates a cost of high
, because higher BMR increases food requirements and energy use during periods of thermoneutral conditions.Abbreviations
BMR
basal metabolic rate
-
FMR
field metabolic rate
-
partial pressure of oxygen
-
T
a
ambient temperature
-
T
b
body temperature
-
T
e
operative temperature
-
maximal aerobic metabolic rate 相似文献
13.
Syun’iti Iwao 《Population Ecology》1976,18(1):243-260
Summary and Conclusion The measurement of spatial association between two species is considered on the basis of interspecies mean crowding. Two indices
of overlapping, γ andC
μ, are derived as geometric and weighted arithmetic means of the same component ratios related to inter- and intraspecies mean
crowdings. Both indices behave in a similar way, ranging from 1 when the distributions of two species are completely overlapped
to 0 when they are completely exclusive with each other. The former is essentially identical with indices proposed byKuno (1968) andPianka (1973), and the latter is a modified form ofMorisita’s (1959)C
δ index. Indices to measure the degree of spatial correlation between species, ω andR
μ, are then derived for both kinds of overlapping indices, which vary from 1 in complete overlapping, through 0 in independent
occurrence, to −1 in complete exclusion.
Various kinds of interspecies association are analyzed using these indices and an extended form of the
regression graph which provides a convenient way of indicating the spatial interrelation between two species as well as distribution
patterns of respective species.
The method presented in this paper may also be applicable to compare temporal distribution patterns between species, similarity
between communities, etc. For such a wider application which includes continuous as well as discrete distributions, the interpretation
of intra- and interspecies mean crowdings is not necessarily appropriate, and hence the concept of mean concentration with
the symbols
and
for intraspecies relation and
and
for interspecies relation is suggested.
This study was supported by Science Research Fund (No. 148041) from the Ministry of Education. 相似文献
14.
D. L. Evans R. J. Rose 《Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology》1988,157(6):791-799
Summary Six Standardbred horses were used to evaluate the time course of pulmonary gas exchange, ventilation, heart rate (HR) and acid base balance during different intensities of constant-load treadmill exercise. Horses were exercised at approximately 50%, 75% and 100% maximum oxygen uptake (
max) for 5 min and measurements taken every 30 s throughout exercise. At all work rates, the minute ventilation, respiratory frequency and tidal volume reached steady state values by 60 s of exercise. At 100%
max, the oxygen consumption (
) increased to mean values of approximately 130 ml/kg·min, which represents a 40-fold increase above resting
. At the low and moderate work rates,
showed no significant change from 30 s to 300 s of exercise. At the high work rate, the mean
at 30 s was 80% of the value at 300 s. The HR showed no significant change over time at the moderate work rate but differing responses at the low and high work rates. At the low work rate, the mean HR decreased from 188 beats/min at 30 s to 172 beats/min at 300 s exercise, whereas at the high work rate the mean HR increased from 204 beats/min at 30 s to 221 beats/min at 300 s exercise. No changes in acid base status occurred during exercise at the low work rate. At the moderate work rate, a mild metabolic acidosis occurred which was nonprogressive with time, whereas the high work rate resulted in a progressive metabolic acidosis with a base deficit of 16 mmol/l by 300 s exercise. It is concluded that the kinetics of gas exchange during exercise are more rapid in the horse than in man, despite the relatively greater change in
in the horse when going from rest to high intensity exercise.Symbols and abbreviations E
minute ventilation
-
V
T
tidal volume
-
oxygen uptake
-
carbon dioxide output
-
oxygen pulse
-
ventilatory equivalent for oxygen
-
ventilatory equivalent for carbon dioxide
- R
respiratory exchange ratio
- HR
heart rate
- SBC
standard bicarbonate
- STPD
standard temperature and pressure dry
- BTPS
body temperature and pressure saturated
-
arterial oxygen content
-
arteriovenous oxygen content difference
- Rf
respiratory frequency 相似文献
15.
The thermodynamics of irreversible processes is derived from the principles of dynamical field theory independently of all
elements of thermostatics, in particular the assumption of local equilibrium. Field thermodynamics proceeds from the premise
that all driving forces experienced by the molecules in a continuum are conservative and arise from scalar potential functions.
Dynamically the temperature potentialT is no different from the pressure potentialp. A field is converted to a force upon multiplication by a scale factor. A potential is converted to potential energy by the
same scale factor. To scale the field −∇p to the force per mole of molecular speciesk, the partial molar, volume
is the scale factor. Similarly the partial molar entropy,
, scales the temperature field. The transition from the scale factors (which are physical parameters) to the systemic variables,
for example
, is not trivial. From the dynamics and the structure of the derived potential energy function are inducted the conjugate
variables such as (p, V
I) and (T, s). The meta-mechanical properties of the thermal variables (T, s) are discovered via the local First Law of Thermodynamics, which relates internal energy, thermal flux, and work, and from
the local Second Law, which prescribes, the possible partitions of internal energy between kinetic, potential, and thermal
energies. From the form of the potential energy come Maxwell's relationships. From the energy partition comes the equation
of continuity for entropy, with its important source term. In contrast to earlier theories of irreversible thermodynamics,
the dissipation function does not include the stress tensor, a constitutive parameter. 相似文献
16.
17.
B. Culik A. J. Woakes D. Adelung R. P. Wilson N. R. Coria H. J. Spairani 《Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology》1990,160(1):61-70
Summary The energy requirements of Adélie penguin (Pygoscelis adeliae) chicks were analysed with respect to body mass (W, 0.145–3.35 kg, n=36) and various forms of activity (lying, standing, minor activity, locomotion, walking on a treadmill). Direct respirometry was used to measure O2 consumption (
) and CO2 production. Heart rate (HR, bpm) was recorded from the ECG obtained by both externally attached electrodes and implantable HR-transmitters. The parameters measured were not affected by hand-rearing of the chicks or by implanting transmitters. HR measured in the laboratory and in the field were comparable. Oxygen uptake ranged from
in lying chicks to
at maximal activity, RQ=0.76. Metabolic rate in small wild chicks (0.14–0.38 kg) was not affected by time of day, nor was their feeding frequency in the colony (Dec 20–21). Regressions of HR on
were highly significant (p< 0.0001) in transmitter implanted chicks (n=4), and two relationships are proposed for the pooled data, one for minor activities (
), and one for walking (
). Oxygen consumption, mass of the chick (2–3 kg), and duration of walking (T, s) were related as
, whereas mass-specific O2 consumption was related to walking speed (S, m·s-1) as
.Abbreviations
bpm
beats per minute
-
D
distance walked (m)
-
ECG
electrocardiogram
-
HR
heart rate (bpm)
-
ns
number of steps
-
RQ
respiratory quotient
-
S
walking speed (m·s-1)
-
T
time walked (s)
-
W
body mass (kg) 相似文献
18.
Effects of ambient temperature and altitude on ventilation and gas exchange in deer mice (Peromyscus maniculatus) 总被引:2,自引:1,他引:1
Mark A. Chappell 《Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology》1985,155(6):751-758
Summary The effects of different ambient temperatures (T
a) on gas exchange and ventilation in deer mice (Peromyscus maniculatus) were determined after acclimation to low and high altitude (340 and 3,800 m).At both low and high altitude, oxygen consumption (
) decreased with increasingT
a atT
a from –10 to 30 °C. The
was 15–20% smaller at high altitude than at low altitude atT
a below 30 °C.Increased
atT
a below thermoneutrality was supported by increased minute volume (
) at both low and high altitude. At mostT
a, the change in
was primarily a function of changing respiration frequency (f); relatively little change occurred in tidal volume (V
T) or oxygen extraction efficiency (O2EE). AtT
a=0 °C and below at high altitude,
was constant due to decliningV
T and O2EE increased in order to maintain high
.At high altitude,
(BTP) was 30–40% higher at a givenT
a than at low altitude, except atT
a below 10 °C. The increased
at high altitude was due primarily to a proportional increase inf, which attained mean values of 450–500 breaths/min atT
a below 0 °C. The
(STP) was equivalent at high and low altitude atT
a of 10 °C and above. At lowerT
a,
(STPD) was larger at low altitude.At both altitudes, respiratory heat loss was a small fraction (<10%) of metabolic heat production, except at highT
a (20–30 °C).Abbreviations
EHL
evaporative heat loss
-
f
respiration frequency
-
HL
a
heat loss from warming tidal air
-
HL
e
evaporative heat loss in tidal air
-
HL
total respiratory heat loss
-
MHP
metabolic heat production
-
O
2
EE
oxygen extraction efficiency
-
RQ
respiratory quotient
-
T
a
ambient temperature
-
T
b
body temperatureT
lc lower critical temperature
-
carbon dioxide production
-
evaporative water loss
-
oxygen consumption
-
minute volume
-
V
T
tidal volume 相似文献
19.
An analytical model is developed to describe the performance of a packed-bed immobilized enzyme reactor in which parallel processes take place. In particular, two-substrate reaction, inhibition of the enzyme by one of the reaction products, and binding of one substrate and/or one product to an added ligand are taken into account. In addition, substrates and product diffusion into the porous catalyst are also considered. Using this model, numerical simulations were performed. The results point to the fact that, when all the above processes occur concomitantly, a variety of performance characteristics can be obtained, depending on the particular values of the related parameters. Moreover, under certain conditions, the reactor performance can be improved by controlled addition of ligand.List of Symbols
A
total concentration of ligand
-
C
1,i
concentration of Substrate-1 in the pores of stage i
-
C
2,i
concentration of Substrate-2 in its free form in the pores of stage i
-
2,i
concentration of the Substrate-2-Ligand Complex in the pores of stage i
-
total concentration of Substrate-2 in the pores of stage i
-
i
concentration of the Product-Ligand Complex in the pores of stage i
-
concentration of the free Product in the pores of stage i
-
total concentration of the Product in the pores of stage i
-
internal (pore) diffusion coefficient for the Substrate-Ligand Complex
-
D
1
internal (pore) diffusion coefficient of Substrate-1
-
D
2
internal (pore) diffusion coefficient of Substrate-2
-
effective (pore) diffusion coefficient for Substrate-2
-
internal (pore) diffusion coefficient for the Product
-
internal (pore) diffusion coefficient for the Product-Ligand Complex
-
effective (pore) diffusion coefficient for the Product
-
K
thermodynamic equilibrium constant for binding Substrate-2 to Ligand
-
K
m,1,K
m,2
Michaelis constants for Substrates-1 and 2, respectively
-
effective Michaelis constant for Substrate-2
-
K
p
thermodynamic equilibrium constant for binding the reaction Product to Ligand
-
effective equilibrium constant for binding Substrate-2 to Ligand
-
effective equilibrium constant for binding the reaction Product to Ligand.
-
K
b
inhibition constant
-
K
q
inhibition constant
-
effective inhibition constant
-
effective inhibition constant
-
k
a, k
d
association and dissociation rate constants for Substrate-2 — Ligand complex
-
association and dissociation constants for Product —Ligand complex
-
n
total number of elementary stages in the reactor
-
Q
volumetric flow rate throughout the reactor
-
R
j,i
reaction rate of Substrate-j in stage i, in terms of volumetric units
-
S
1,0
concentration of Substrate-1 in the reactor feed
-
total concentration of Substrate-2 in the reactor feed
-
S
1,i–1,S
1,i
concentration of Substrate-1 in the bulk phase leaving stages i–1 and i, respectively
-
S
2,i
concentration of Substrate-2 in its free form, in the bulk phase leaving stage i
-
2,i–1,
2,i
concentration of Substrate-2 in the bulk phase leaving stage i–1 and i, respectively
-
total concentration of Substrate-2 in the bulk phase leaving stages i–1 and i, respectively
-
i
concentration of the Product-Ligand Complex in the bulk phase of stage i
-
concentration of free Product in the bulk phase of stage i
-
total concentration of Product in the bulk phase of stage i
-
V
total volume of the reactor
-
V
m
maximal reaction rate in terms of volumetric units
-
y
axial coordinate of the pores
-
y
0
depth of the pores
Greek Symbols
1
dimensionless parameter
-
dimensionless parameter
-
dimensionless parameter
-
1
dimensionless parameter
-
dimensionless parameter
-
1,i
dimensionless concentration of Substrate-1 in pores of stage i
-
dimensionless total concentration of Substrate-2 (in both free and bound form) in pores of stage i
-
dimensionless total concentration of the reaction product in the pores of stage i
-
1
dimensionless parameter
-
dimensionless parameter
-
dimensionless parameter
-
dimensionless parameter
-
dimensionless parameter
-
dimensionless position along the pore
-
volumetric packing density of catalytic particles (dimensionless)
-
porosity of the catalytic particles (dimensionless)
-
1,i
dimensionless concentration of Substrate-1 in the bulk phase of stage i
-
dimensionless total concentration of Substrate-2 (in both free and bound form) in the bulk phase of stage i 相似文献
20.
Pierre Dejours Jean-Paul Truchot 《Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology》1988,158(3):387-391
Summary In the intertidal shore crab,Carcinus maenas, pH and
values of the prebranchial venous hemolymph,
and
, the PO2 values of the arterialized cardiac hemolymph,
, were measured, and the ventilatory activity was assessed by measuring the hydrostatic pressures at the exits of the epibranchial cavities, under four environmental conditions: normoxic water, normoxic air, hypoxic gas, hyperoxic gas.In the crab breathing normoxic air,
was lower and
higher than in animals breathing normoxic water. With the switch to hypoxic gas, ventilation increased and
and
decreased. With the switch to hyperoxic gas, ventilation decreased,
and
increased and
decreased.Thus these crabs breathing air were not as well oxygenated as when breathing air-equilibrated water, and because of their low
, they were relatively hypervetilating and hypocapnic compared to air-breathing vertebrates. Hyperoxic breathing, increasing
and reducing ventilatory drive, led to increased
. Conversely,
was reduced by hypoxic breathing. These observations suggest that the gas exchanger of intertidal crabs is not as successfully designed for air breathing as that of land-colonizing insects and air-breathing vertebrates. 相似文献