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A fundamental challenge facing biologists is to identify DNA binding sites for unknown regulatory factors, given a collection of genes believed to be coregulated. The program YMF identifies good candidates for such binding sites by searching for statistically overrepresented motifs. More specifically, YMF enumerates all motifs in the search space and is guaranteed to produce those motifs with greatest z-scores. This note describes the YMF web software, available at http://bio.cs.washington.edu/software.html. 相似文献
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Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer
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Jennifer M Thomas‐Ahner Dayong Wu Xiangtao Liu Zhenqing Ye Liguo Wang Benjamin Sunkel Cassandra Grenade Junsheng Chen Debra L Zynger Pearlly S Yan Jiaoti Huang Kenneth P Nephew Tim H‐M Huang Shili Lin Steven K Clinton Wei Li Victor X Jin Qianben Wang 《The EMBO journal》2015,34(4):502-516
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