The neural bases of social intention understanding: the role of interaction goals

Decoding others' intentions is a crucial aspect of social cognition. Neuroimaging studies suggest that inferring immediate goals engages the neural system for action understanding (i.e. mirror system), while the decoding of long-term intentions requires the system subserving the attribution of mental states (i.e. mentalizing). A controversial issue, stimulated by recent inconsistent results, concerns whether the two systems are concurrently vs. exclusively involved in intention understanding. This issue is particularly relevant in the case of social interactions, whose processing has been mostly, but not uncontroversially, associated with the mentalizing system. We tested the alternative hypothesis that the relative contribution of the two systems in intention understanding may also depend on the shared goal of interacting agents. To this purpose, 27 participants observed social interactions differing in their cooperative vs. affective shared goal during functional-Magnetic-Resonance-Imaging. The processing of both types of interactions activated the right temporo-parietal junction involved in mentalizing on action goals. Additionally, whole-brain and regions-of-interest analyses showed that the action understanding system (inferior prefrontal-parietal cortex) was more strongly activated by cooperative interactions, while the mentalizing-proper system (medial prefrontal cortex) was more strongly engaged by affective interactions. These differences were modulated by individual differences in empathizing. Both systems can thus be involved in understanding social intentions, with a relative weighting depending on the specific shared goal of the interaction.     

Mechanisms in group formation and cohesion in Tupaia glis Diard, 1820. Results of long-term studies of a family group]

In long-term studies of a family group, all the partner-orientated interactions are quantitatively registered and analysed in connection with the usuage of space by the animals. From this, the connections between the interactions and respectively status forms of the group members are recognizable. During the growing-up period of the juveniles in the group, beginning with the first leaving of the nest box at the age of about 33 days, three phases can be differentiated. A phase of "integration" of about 5 to 8 days, in which the behavior patterns between adults and juveniles are polarized on licking mouth with the adults and scent marking the juveniles, is obviously the presupposition for including the rising generation in the relational system (including the space system) of the adults. This phase is followed by a "neutral phase", lasting about 30 days, during which the juveniles stand in connection with the adults by means of a space bonding, in which relatively few interactions occur. Through the joint use of parental resting places and through the resting in close spatial neighbourhood, a true retention of experience for the juveniles must be thought of. At the age of about 60 days an 'ambivalent phase" begins, in which the contacts between parents and the offspring increases again, with an alteration and a superposition of sexual and agonistic interactions. Besides, the sex-specific differences become recognizable: the male interacts with his daughters increasingly sexually, with the sons he is more and more aggressive; the relations of the mother with the female offspring are ambivalent, during which she shows male behaviour patterns and with her sons the female scarcely has contact. Lying in bodily contact has, beyond the importance for a pair bonding, significance for a group bonding. Licking the mouth as an element of the care system (infantile behavior) can be used as an appeasement gesture. The age of 90--100 days, in which the parents frequently have aggressive gesture with their offspring of the same sex, is regarded as the time of reaching sexual maturity. A longer lasting integration of a female offspring (and a male) is described. The social organization of Tupaia glis is based on a permanent pair bonding. Through the addition of the young, a parental family with a maximum of two generations of brothers and sisters can arise. Limiting factors of the group size are incest barriers, a density stress, and the possibilities of communication of the species themselves.     

The Three Semiotic Lives of Domestic Cats: A Case Study on Animal Social Cognition

The social cognition of domestic cats (Felis catus) is a scarcely studied topic due to the reputation of the animal as individualistic. Nevertheless, cats are capable of cognitively demanding cooperative activities such as a communal nest-moving. The cognitive abilities of free-ranging cats are evaluated against the background of the shared intentionality hypothesis, proposed by a research group of Michael Tomasello. Although their comparative studies are carried out on chimpanzees, they are valuable as a source of conceptual work linking empirical cognitive studies with the philosophical accounts of joint agency. We critically analyze theoretical cognitive concepts interpreting the triadic interactions of great apes and the collective hunting among chimpanzees. Contrary to the shared intentionality hypothesis, it is argued that cats have cognitive abilities to share attention, truly cooperate and constitute shared meanings. Finally, we introduce the concept of the natural interaction ritual by Randall Collins and outline its significance for our case study about cats as well as for a general biosemiotic theory of the development of symbols.     

Glycosylation and glycan interactions can serve as extracellular machinery facilitating clathrin‐independent endocytosis

In contrast to clathrin‐mediated endocytosis (CME) which is well characterized and understood, little is known about the regulation and machinery underlying clathrin‐independent endocytosis (CIE). There is also a wide variation in the requirements each individual CIE cargo has for its internalization. Recent studies have shown that CIE is affected by glycosylation and glycan interactions. We briefly review these studies and explore how these studies mesh with one another. We then discuss what this sensitivity to glycan interactions could indicate for the regulation of CIE. We address the spectrum of responses CIE has been shown to have with respect to changes in glycan interactions and attempt to reconcile disparate observations onto a shared conceptual landscape. We focus on the mechanisms by which cells can alter the glycan interactions at the plasma membrane and propose that glycosylation and glycan interactions could provide cells with a tool box with which cells can manipulate CIE. Altered glycosylation is often associated with a number of diseases and we discuss how under different disease settings, glycosylation‐based modulation of CIE could play a role in disease progression.      

"Decisions and Dispositions": Socializing Spatial Archaeology

Concerns with spatial dimensions and social inference have long histories in archaeology. However, the two histories are not always conjoined. This article considers changing understandings of space in archaeology in the last half century, and the variable nature of what "social" has denoted and connoted during that same span. The review highlights recurring calls for a social archaeology, and the degree to which, in such instances, social inference has been expressed in spatial terms, especially as these have recognized people's "decisions and dispositions" as shaping the archaeological record. Life histories of place receive special attention as ways of discerning the existence and social impact of such decisions and dispositions. These life histories constitute an arena in which archaeologists from diverse theoretical perspectives can offer complementary insights. Moreover, they exemplify ways in which social and spatial inferences in archaeology contribute to wider understanding of human experience. [Keywords: archaeology, social, space, place, life history]     

Mass customization research: trends,directions, diffusion intensity,and taxonomic frameworks

Mass customization (MC) as a business strategy is designed to simultaneously compete on two rival competitive priorities—the price and customization level of a product. MC academics and experts have gone a step further. They suggest that MC is a unique strategy whose implementation promises across-the-board improvement in all four of the competitive priorities (price, quality, flexibility, and speed) simultaneously. Its growing adoption by businesses in recent years, the steep rise in success stories associated with MC, and the voluminous body of publications in a short period of its existence have created a need to study the directions, trends, application potential, and research strategies embedded in these publications. Accordingly, this paper studies and analyzes the trends and directions of the research published in 1,124 MC publications that have appeared in journals and magazines since the inception of the term mass customization in 1987 by Stan Davis in his classic book Future Perfect. Statistical trend analyses are conducted to study the vitality and health of the field of MC using number of publications and number of publication outlets and their respective trends. The publication outlet data conform to an S curve, establishing maturity of the MC field. The publication data show that the MC field has passed through four stages of growth: incubation or slow (1987–1992), exponential (1993–2003), stable and matured (2003–2005). There is a slight dip in 2006 in terms of publication outlets; there are, however, confirmatory factors that indicate that the dip in 2006 may be an outlier. This paper also suggests developing a clear understanding of the value and type of research embodied in MC publications through three types of taxonomic analyses. The frameworks for all three taxonomies are set forth, two of which have been previously employed in other areas of OR/MS (Reisman and Kirschnik, Oper Res 42(4):577–588, 1994; Oper Res 43(5):731–740, 1995): The first taxonomic framework first classifies the paper as a theory paper or an application paper. At the second stage, the application content of the publication is determined based on a five-point scale ranging from simple modeling of the real world to bona fide real-world application. The second taxonomic framework suggests usage of a taxonomy comprised of seven distinct types of research strategies. The former analysis provides important information about the application worthiness of the MC publications and hence their usefulness to the real world. The second analysis provides information about the type of research strategies used by MC researchers, which, in turn, allows drawing conclusions about the quality and rigor of such research. The third taxonomic framework suggested recommends classification of all publications among multi-level containers based on the disciplines that intersect with MC and their branches.     

From "Rights" to "Ritual": AIDS Activism in South Africa

In this article, I investigate how the moral politics of HIV/AIDS activism in South Africa is contributing toward new forms of citizenship that are concerned with both rights-based struggles and with creating collectively shared meanings of the extreme experiences of illness and stigmatization of individual HIV/AIDS sufferers. I argue that it is precisely the extremity of the "near death" experiences of full-blown AIDS, and the profound stigma and "social death" associated with the later stages of the disease, that produce the conditions for HIV/AIDS survivors' commitment to "new life" and social activism. It is the activist mediation and retelling of these traumatic experiences that facilitates HIV/AIDS activist commitment and grassroots mobilization. It is also the profound negativity of stigma and social death that animates the activist's construction of a new positive HIV-positive identity and understanding of what it means to be a citizen–activist and member of a social movement.     

"The Vulgar Spirit of Blogging": On Language, Culture, and Power in Persian Weblogestan

This article is an ethnographic study of Persian-language weblogs (blogs), focusing on a divisive argument among Iranian bloggers that came to be known as the "vulgarity debate." Sparked by a controversial blogger who ridiculed assertions that Islam was compatible with human rights, the debate revolved around the claim that blogging had a "vulgar spirit" that made it easy for everything from standards of writing to principles of logical reasoning to be undermined. My study focuses primarily on the linguistic side of the controversy: I analyze blogging as an emergent speech genre and identify the structural features and social interactions that make this genre seem "vulgar." I also examine the controversy as a confrontation between bloggers with unequal access to cultural capital and a struggle over "intellectualist" hegemony. In the conclusion, I use the construct of "deep play" to weave together multiple layers of structure, explanation, and meaning in the debate.     

The 30th anniversary of <Emphasis Type="Italic">Ecological Research</Emphasis>: past,present, and future

In 2016, Ecological Research (ER) celebrated its 30th anniversary. ER’s goal is to be the leading ecological, evolutionary, and biodiversity journal in Asia. This article introduces the development of ER, improvements to its editorial system and their outcomes, and the strategies designed to achieve this goal. ER has already become a leading comprehensive and international publication as shown by statistical evidence and its strong editorial foundation. However, some members of the Ecological Society of Japan (ESJ) retain impressions of an old stereotype about ER. The discrepancy between the current status of the journal and its stereotype may explain why submissions from Japan remain static. A new article category for ER, Biodiversity in Asia, was created to encourage Asian studies. In addition, the Forum category is dedicated to promoting a broad understanding of the ESJ’s various activities. To promote open science, the proportion of open access articles in the journal is increasing. The publication of Data papers has been accelerated to improve the public availability of excellent open data sets. ER symposia and seminars provide good opportunities for members to participate. ER financially supports the invitation of scientists internationally to facilitate research exchanges with other countries and consequently promotes the internationalization of the ESJ. The ESJ is open to the world’s ecologists, and your participation in developing ER is welcome.     

Movement patterns, social dynamics, and the evolution of cooperation

The structure of social interactions influences many aspects of social life, including the spread of information and behavior, and the evolution of social phenotypes. After dispersal, organisms move around throughout their lives, and the patterns of their movement influence their social encounters over the course of their lifespan. Though both space and mobility are known to influence social evolution, there is little analysis of the influence of specific movement patterns on evolutionary dynamics. We explored the effects of random movement strategies on the evolution of cooperation using an agent-based prisoner’s dilemma model with mobile agents. This is the first systematic analysis of a model in which cooperators and defectors can use different random movement strategies, which we chose to fall on a spectrum between highly exploratory and highly restricted in their search tendencies. Because limited dispersal and restrictions to local neighborhood size are known to influence the ability of cooperators to effectively assort, we also assessed the robustness of our findings with respect to dispersal and local capacity constraints. We show that differences in patterns of movement can dramatically influence the likelihood of cooperator success, and that the effects of different movement patterns are sensitive to environmental assumptions about offspring dispersal and local space constraints. Since local interactions implicitly generate dynamic social interaction networks, we also measured the average number of unique and total interactions over a lifetime and considered how these emergent network dynamics helped explain the results. This work extends what is known about mobility and the evolution of cooperation, and also has general implications for social models with randomly moving agents.     

Nesting patterns,ecological correlates of polygyny and social organization in the neotropical arboreal ant <Emphasis Type="Italic">Odontomachus hastatus</Emphasis> (Formicidae,Ponerinae)

Queen number varies in the population of O. hastatus in SE Brazil. Here, we evaluate how nesting ecology and colony structure are associated in this species, and investigate how reproduction is shared among nestmate queens. Queen number per colony is positively correlated with nesting space (root cluster of epiphytic bromeliads), and larger nest sites host larger ant colonies. Plant samplings revealed that suitable nest sites are limited and that nesting space at ant-occupied bromeliads differs in size and height from the general bromeliad community. Dissections revealed that queens in polygynous colonies are inseminated, have developed ovaries, and produce eggs. Behavioral observations showed that reproduction in polygynous colonies is mediated by queen–queen agonistic interactions that include egg cannibalism. Dominant queens usually produced more eggs. Field observations indicate that colonies can be initiated through haplometrosis. Polygyny in O. hastatus may result either from groups of cofounding queens (pleometrosis) or from adoption of newly mated queens by established colonies (secondary polygyny). Clumping of bromeliads increases nest space and probably adds stability through a strong root system, which may promote microhabitat selection by queens and favor pleometrosis. Rainstorms that frequently knock down bromeliads can be a source of colony break-up and may promote polygyny. Bromeliads are limited nest sites and may represent a risk for young queens leaving a suitable nest, thus favoring secondary polygyny. Although proximate mechanisms mediating queen number are poorly understood, this study suggests that heterogeneous microhabitat conditions probably contribute to the coexistence of variable forms of social structure in O. hastatus.     

A more complete, complexed and structured interactome

Multiprotein complexes are key players in virtually all important cellular processes. The past year has seen the publication of several papers that have illuminated what we know about the number and composition of these molecular machines, using high-throughput purification methods. Other studies have illuminated structural and functional aspects of protein interactions, networks and molecular assemblies. As a result, we have a more complete view of how many complexes are in living systems, what they look like and the roles they play in the cell.     

How territorial animals compete for divisible space: a learning-based model with unequal competitors

It is widely assumed that aggressive behavior affects space acquisition in territorial species, but to date most workers have focused on competition for indivisible space, that is, space that cannot be divided or shared. We present a learning-based model that investigates the effects of aggressive interactions on space acquisition when unequal competitors arrive and settle in patches of divisible space. This model assumes that aggressive interactions act as punishment, in the sense that previous aggressive interactions in a given area reduce an individual's likelihood of returning to that area. Individually based, spatially explicit simulations incorporating this and other assumptions were used to investigate the effects of different types of aggressive interactions on the space use of individuals and dyads settling in divisible space. At the individual level, final space use was related to the amount of punishment that individuals inflicted on their opponents during aggressive interactions; in general, highly aggressive individuals acquired larger, more exclusive home ranges than less aggressive individuals. At the dyadic level, the division or sharing of space between competitors depended on both the relative and absolute punishment that competitors inflicted on one another during aggressive interactions. Aggressive interactions in which both participants strongly punished one another (e.g., escalated fights) produced mutually exclusive home ranges, interactions with intermediate levels of punishment produced asymmetrical space use patterns proportional to asymmetries in punishment levels, and interactions involving little punishment for either participant generated large home ranges with extensive home range overlap. Overall, our model implies that territorial animals need not "win" aggressive interactions to win divisible space, that repeatedly "nagging" an opponent may also be a viable strategy for gaining space, and that a learning-based approach can account for puzzling patterns in the territorial literature, for example, observations of individuals who acquire space by initiating aggressive interactions that they never win.     

The cost of defeat: Capuchin groups travel further,faster and later after losing conflicts with neighbors

Although competition between social groups is central to hypotheses about the evolution of human social organization, competitive interactions among group‐mates are thought to play a more dominant role in shaping the behavior and ecology of other primate species. However, few studies have directly tested the impact of intergroup conflicts in non‐human primates. What is the cost of defeat? To address this question, the movements of six neighboring white‐faced capuchin (Cebus capucinus) social groups living on Barro Colorado Island, Panama were tracked simultaneously using an Automated Radio Telemetry System (ARTS), for a period of six months. Groups moved 13% (441 m) further on days they lost interactions compared with days they won interactions. To cover these larger distances, they traveled faster, stopped less frequently, and remained active later in the evening. Defeat also caused groups to alter their patterns of space use. Losing groups had straighter travel paths than winning groups, larger net displacements and were more likely to change their sleeping site. These results demonstrate that losing groups pay increased travel costs and suggest that they forage in low‐quality areas. They provide some of the first direct evidence that intergroup conflicts have important energetic consequences for members of competitively unsuccessful primate social groups. A better understanding of how intergroup competition impacts patterns of individual fitness is thus needed to clarify the role that this group‐level process plays in shaping the evolution of human‐ and non‐human primate behavior. Am J Phys Anthropol 152:79–85, 2013. © 2013 Wiley Periodicals, Inc.     

Kickoff to Conflict: A Sequence Analysis of Intra-State Conflict-Preceding Event Structures

While many studies have suggested or assumed that the periods preceding the onset of intra-state conflict are similar across time and space, few have empirically tested this proposition. Using the Integrated Crisis Early Warning System''s domestic event data in Asia from 1998–2010, we subject this proposition to empirical analysis. We code the similarity of government-rebel interactions in sequences preceding the onset of intra-state conflict to those preceding further periods of peace using three different metrics: Euclidean, Levenshtein, and mutual information. These scores are then used as predictors in a bivariate logistic regression to forecast whether we are likely to observe conflict in neither, one, or both of the states. We find that our model accurately classifies cases where both sequences precede peace, but struggles to distinguish between cases in which one sequence escalates to conflict and where both sequences escalate to conflict. These findings empirically suggest that generalizable patterns exist between event sequences that precede peace.     

Calcium-binding and temperature induced transitions in equine lysozyme: new insights from the pCa-temperature "phase diagrams"

The most universal approach to the studies of metal binding properties of single-site metal binding proteins, i.e., construction of a "phase diagram" in coordinates of free metal ion concentration-temperature, has been applied to equine lysozyme (EQL). EQL has one relatively strong calcium binding site and shows two thermal transitions, but only one of them is Ca(2+)-dependent. It has been found that the Ca(2+)-dependent behavior of the low temperature thermal transition (I) of EQL can be adequately described based upon the simplest four-states scheme of metal- and temperature-induced structural changes in a protein. All thermodynamic parameters of this scheme were determined experimentally and used for construction of the EQL phase diagram in the pCa-temperature space. Comparison of the phase diagram with that for alpha-lactalbumin (alpha-LA), a close homologue of lysozyme, allows visualization of the differences in thermodynamic behavior of the two proteins. The thermal stability of apo-EQL (transition I) closely resembles that for apo-alpha-LA (mid-temperature 25 degrees C), while the thermal stabilities of their Ca(2+)-bound forms are almost indistinguishable. The native state of EQL has three orders of magnitude lower affinity for Ca(2+) in comparison with alpha-LA while its thermally unfolded state (after the I transition) has about one order lower (K = 15M(-1)) affinity for calcium. Circular dichroism studies of the apo-lysozyme state after the first thermal transition show that it shares common features with the molten globule state of alpha-LA.     

Male social activity in the small Indian mongoose<Emphasis Type="Italic">Herpestes javanicus</Emphasis>

The mongoose family, Herpestidae, includes several species that comprise the most social small Carnivora. The small Indian mongooseHerpestes javanicus (E. Geoffroy Saint-Hilaire, 1818), a South Asian species that has been introduced to numerous Caribbean and Pacific islands, has not been reported to show complex sociality. A radio-tracking study conducted on Oahu, Hawaii, revealed that a group of at least 5, and perhaps more than 10, large males in the study area shared a single, large home range during the breeding season. Members of this group spent far more time than expected within 20 m of fellow members. Group members frequently shared dens, sleeping within 50 cm of each other. Females maintained very small, overlapping home ranges inside the male group’s range. Male breeding coalitions have previously been reported in a congeneric species, the slender mongooseHerpestes sanguineus.     

Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes

BACKGROUND: Several methods have been developed for creating Cys2His2 zinc finger proteins that recognize novel DNA sequences, and these proteins may have important applications in biological research and gene therapy. In spite of this progress with design/selection methodology, fundamental questions remain about the principles that govern DNA recognition. One hypothesis suggests that recognition can be described by a simple set of rules--essentially a "recognition code"--but careful assessment of this proposal has been difficult because there have been few structural studies of selected zinc finger proteins. RESULTS: We report the high-resolution cocrystal structures of two zinc finger proteins that had been selected (as variants of Zif268) to recognize a eukaryotic TATA box sequence. The overall docking arrangement of the fingers within the major groove of the DNA is similar to that observed in the Zif268 complex. Nevertheless, comparison of Zif268 and the selected variants reveal significant differences in the pattern of side chain-base interactions. The new structures also reveal side chain-side chain interactions (both within and between fingers) that are important in stabilizing the protein-DNA interface and appear to play substantial roles in recognition. CONCLUSIONS: These new structures highlight the surprising complexity of zinc finger-DNA interactions. The diversity of interactions observed at the protein-DNA interface, which is especially striking for proteins that were all derived from Zif268, challenges fundamental concepts about zinc finger-DNA recognition and underscores the difficulty in developing any meaningful recognition code.     

The "promiscuous drug concept" with applications to Alzheimer's disease

Arguably, Alzheimer's disease (AD) is a multifactorial syndrome, rather than single disease, arising from a complex array of neurochemical factors. Numerous studies on the molecular pathogenesis of AD implicate a diversity of factors ranging from neurotoxic peptides (beta-amyloid) to inflammatory processes (interleukins), but all culminating in a common neuropathology. This diversity of molecular causation is an impediment to the design of effective therapies for AD. To address this design problem, we sought to identify a single, common motif (a "common receptor") shared by multiple structurally and functionally diverse proteins implicated in AD. This search revealed the presence of a common BBXB peptide motif and upon refinement, an AXBBXB motif; these regions can be exploited for the design of a "promiscuous drug" that exploits a "one-drug-multiple-receptors" therapeutic strategy for AD.