Structure of the ancient TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium

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Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED

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Structural Basis for a Convergent Immune Response against Ebola Virus

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Ligand Incorporation into Protein Microcrystals for MicroED by On-Grid Soaking

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Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia

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Cone-shaped HIV-1 capsids are transported through intact nuclear pores

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Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis

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ER-to-Golgi protein delivery through an interwoven,tubular network extending from ER

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Negative-Stain Electron Microscopy Reveals Dramatic Structural Rearrangements in Ni-Fe-S-Dependent Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase

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A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin

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Super-resolution imaging reveals cytoskeleton-dependent organelle rearrangement within platelets at intermediate stages of maturation

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Compressed sensing for electron cryotomography and high-resolution subtomogram averaging of biological specimens

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Structure of the peripheral arm of a minimalistic respiratory complex I

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ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation

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Residue-level error detection in cryoelectron microscopy models

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Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea

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Development of an α-synuclein positron emission tomography tracer for imaging synucleinopathies

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Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC

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Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture,phosphorylation, and ubiquitylation

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The structure of an Hsp90-immunophilin complex reveals cochaperone recognition of the client maturation state

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