Structure-guided optimization of light-activated chimeric G-protein-coupled receptors

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Current processes and future challenges of photoautotrophic production of acetyl-CoA-derived solar fuels and chemicals in cyanobacteria

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Co-crystallization with diabodies: A case study for the introduction of synthetic symmetry

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Structure and engineering of the minimal type VI CRISPR-Cas13bt3

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Engineered miniature CRISPR-Cas system for mammalian genome regulation and editing

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Cross-kingdom expression of synthetic genetic elements promotes discovery of metabolites in the human microbiome

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Computational Modeling of Protein Stability: Quantitative Analysis Reveals Solutions to Pervasive Problems

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Engineering a modular double-transmembrane synthetic receptor system for customizing cellular programs

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Synthetic regulatory genomics uncovers enhancer context dependence at the Sox2 locus

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helixCAM: A platform for programmable cellular assembly in bacteria and human cells

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Rational engineering of a synthetic insect-bacterial mutualism

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Cas11 enables genome engineering in human cells with compact CRISPR-Cas3 systems

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Massively parallel base editing to map variant effects in human hematopoiesis

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Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair

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Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain

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Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine

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Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species

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Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior

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Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity

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IPRO+/−: Computational Protein Design Tool Allowing for Insertions and Deletions

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