Structure and engineering of the minimal type VI CRISPR-Cas13bt3

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Structure of the enterococcal T4SS protein PrgL reveals unique dimerization interface in the VirB8 protein family

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Conformational Dynamics and Functional Implications of Phosphorylated β-Arrestins

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A set of closely related methyltransferases for site-specific tailoring of anthraquinone pigments

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Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site

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A conformational change in the N terminus of SLC38A9 signals mTORC1 activation

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Structural analysis of the architecture and in situ localization of the main S-layer complex in Deinococcus radiodurans

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Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor

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An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis

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Structural and functional insights into the mechanism by which MutS2 recognizes a DNA junction

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Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7–11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9

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TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation

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A Global Ramachandran Score Identifies Protein Structures with Unlikely Stereochemistry

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Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa

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Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain

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Heterocomplex structure of a polyketide synthase component involved in modular backbone halogenation

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Unique Structural Features of Mammalian NEIL2 DNA Glycosylase Prime Its Activity for Diverse DNA Substrates and Environments

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Structure-guided design of a perampanel-derived pharmacophore targeting the SARS-CoV-2 main protease

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Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered δ-Protocadherins

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Regulation of GTPase function by autophosphorylation

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