Decoupling the Roles of Cell Shape and Mechanical Stress in Orienting and Cueing Epithelial Mitosis

1. Download high-res image (292KB)
2. Download full-size image

     

The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair

1. Download high-res image (230KB)
2. Download full-size image

     

Structural Insights into ceNAP1 Chaperoning Activity toward ceH2A-H2B

1. Download : Download high-res image (248KB)
2. Download : Download full-size image

     

Species-Specific Mechanisms of Neuron Subtype Specification Reveal Evolutionary Plasticity of Amniote Brain Development

1. Download high-res image (180KB)
2. Download full-size image

     

The Listeriolysin O PEST-like Sequence Co-opts AP-2-Mediated Endocytosis to Prevent Plasma Membrane Damage during Listeria Infection

1. Download high-res image (161KB)
2. Download full-size image

     

Circadian Regulation of Cochlear Sensitivity to Noise by Circulating Glucocorticoids

1. Download : Download high-res image (273KB)
2. Download : Download full-size image

     

IAPs Regulate Distinct Innate Immune Pathways to Co-ordinate the Response to Bacterial Peptidoglycans

1. Download high-res image (237KB)
2. Download full-size image

     

HLH-2/E2A Expression Links Stochastic and Deterministic Elements of a Cell Fate Decision during C. elegans Gonadogenesis

1. Download : Download high-res image (229KB)
2. Download : Download full-size image

     

Genetically Defined Functional Modules for Spatial Orienting in the Mouse Superior Colliculus

1. Download : Download high-res image (206KB)
2. Download : Download full-size image

     

USP2a Supports Metastasis by Tuning TGF-β Signaling

1. Download high-res image (136KB)
2. Download full-size image

     

Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination

1. Download high-res image (132KB)
2. Download full-size image

     

Bayesian Confidence Intervals for Multiplexed Proteomics Integrate Ion-statistics with Peptide Quantification Concordance,

1. Download : Download high-res image (74KB)
2. Download : Download full-size image

Highlights

• •Bayesian Beta-Binomial model integrates ion statistics with peptide ratio agreement.
• •Model appropriately interprets information from low signal peptides.
• •Confidence can be assigned even without replicates.
• •Model adds sensitivity to detection of small changes.

     

Two Parallel Pathways Assign Opposing Odor Valences during Drosophila Memory Formation

1. Download high-res image (248KB)
2. Download full-size image

     

Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race

1. Download high-res image (273KB)
2. Download full-size image

     

A Mammalian Mitophagy Receptor,Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy

1. Download high-res image (273KB)
2. Download full-size image

     

Chemical Crosslinking Mass Spectrometry Reveals the Conformational Landscape of the Activation Helix of PPARγ; a Model for Ligand-Dependent Antagonism

1. Download high-res image (192KB)
2. Download full-size image

     

B1 Cell IgE Impedes Mast Cell-Mediated Enhancement of Parasite Expulsion through B2 IgE Blockade

1. Download high-res image (326KB)
2. Download full-size image

     

Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability

1. Download high-res image (161KB)
2. Download full-size image

     

Commonly Used Insect Repellents Hide Human Odors from Anopheles Mosquitoes

1. Download : Download high-res image (177KB)
2. Download : Download full-size image

     

Large-Scale Phosphoproteomics Reveals Shp-2 Phosphatase-Dependent Regulators of Pdgf Receptor Signaling

1. Download high-res image (168KB)
2. Download full-size image